ABSTRACT
【Objective】 To study and analyze the characteristics of 56-60 years old apheresis platelet donors and the results of pre-donation blood testing in Tianjin, so as to provide reference for the management of blood stations and the maintenance and retention of blood donors. 【Methods】 The information of platelet donors were collected by Tianjin Blood Center from July 1, 2012 to June 30, 2021.The donors aged 56-60(the observation group) were compared with donors aged 18-55(the control). The number of blood donations, male to female ratio, donation frequency, proportion of two-therapeutic-amount donation, rate of deferred donation, incidence of adverse reactions to blood donation, etc of the two groups were studied. The pre-donation test results of the two groups were also compared through the analysis of the unqualified factors of blood routine. 【Results】 From 2012 to 2021, there were 2 837 platelet donors aged 56-60 in Tianjin, and the donation frequency and proportion of two-therapeutic-amount donation were significantly higher than those in the control. The blood routine indexes were significantly different between two groups, but all fluctuated within the normal range(P<0.05). More donors in the observation group than the control were deferred due to unqualified blood routine indexes, mainly caused by Hb deferral. 【Conclusion】 In the past 9 years, the number of apheresis platelet donors aged 56-60 in Tianjin has been stablely increasing. Elderly donors always meet the health requirements of donations according to the results of blood tests. Close monitor of the blood routine indexes, however, should be paid to such population to ensure the elderly donor health and donation safety.
ABSTRACT
【Objective】 To analyze the changes of blood routine and platelet related parameters of the elderly apheresis platelet donors since the first donation, so as to ensure the health and platelet quality of the elderly apheresis donors. 【Methods】 From 2019 to 2021, a total of 69 apheresis platelet donors in our center, aged 55-60 years old, involving 3400 occasions of donation, were enrolled in this study. The change trends of blood routine and platelet related parameters before and after the age of 55 were retrospectively analyzed. One way ANOVA was used for group comparison, and Pearson correlation analysis of platelet parameters was performed. 【Results】 The values of blood routine and platelet related parameters were higher in men than in women (P0.05). As for the males in comparison of the parameters before 55 years old, WBC decreased significantly after 55 years of age (P0.05). The changes of PDW, MPV and P-LCR were consistent and showed a linear positive correlation. 【Conclusion】 The blood routine tests of the elderly apheresis platelet donors were all within the normal range and the proportion was relatively stable. Personalized blood donation schemes should be customized for the elderly blood donors and the health management of blood donors should be implemented.
ABSTRACT
【Objective】 To study and analyze the fluctuation of peripheral blood of apheresis platelet donors aged 56~60, so as to provide data support for safe recruitment and retention of elderly donorsin China. 【Methods】 Elderly apheresisplatelet donors, aged 56~60, donated for 6 769 occasions from 2017 to 2019 in Guangzhou Blood Center were analyzed retrospectively and grouped by gender and age. The fluctuation of peripheral blood was analyzed byone way ANOVA.Further pairwise comparison was carried out by Turky if there were statistical differences. 【Results】 All the peripheral blood levels were statistically significant between men and women aged around 56 (P<0.05). The Plt(×109 / L), RBC(×1012 / L) and Hb(g/L) of women after and before 56 were (274.33±49.47) vs (296.61±44.89), (4.48±0.35) vs (4.4±0.3), and (125.87±9.08) vs (128.33±8.79), respectively, and the differences were statistically significant (P<0.05), while no differences was noticed between them inWBC(×109 / L) and Hct, (6.29±1.36) vs (6.26±1.46) and (0.39±0.05) vs (0.39±0.02), respectively(P>0.05). The RBC(1012 / L), Hb(g/L), WBC(×109 / L) and Hctof men after and before 56 were (4.94±0.39) vs (4.91±0.35), (137.15±12.83) vs (141.29±10.67), (5.77±1.23) vs (6.03±1.26) and (0.42±0.03) vs (0.42±0.03), respectively, and the differences were statistically significant (P<0.05), and no significant difference was noticed in Plt(×109 / L)(283.94±59.63) vs (283.5±62.7)(P>0.05). There was no significant difference in Plt between men and women after 56 (P>0.05). The RBC, Hb and Hct of men around 56 were higher than those of women (P<0.05). The deferral rate of pretransfusion blood testing increased as the platelet donors were older than 56, showing statistical significance(P<0.05). 【Conclusion】 Fluctuation of peripheral blood levelof platelet donors aged 56~60 occurred when they were around 56 years old, but within the normal range.Therefore, blood donation is generally safe under the current policy. As the physiological regulation function of these donors has decreased, the monitoring of peripheral blood routine before and after blood donation needs to be strengthened to ensure blood quality and the health of elderly platelet donors.