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1.
Chinese Journal of Biochemical Pharmaceutics ; (6): 263-265, 2017.
Article in Chinese | WPRIM | ID: wpr-511524

ABSTRACT

Objective To study the clinical significance of dexamethasone (DT) in the combined spinal and epidural anesthesia for delivery of elderly parturient women. Methods 134 elderly parturient women were selected as the research object, and randomly divided into two groups. 69 cases in DT group received intramuscular injection of dexamethasone and combined anesthesia, while 65 cases in INN group received intramuscular injection of tramadol (INN) and combined spinal and epidural anesthesia. The anesthetic effect of the two groups were observed. Results After treatment, the interleukin (IL-6), myeloperoxidase (MPO), tumor necrosis factor-α (TNF-α) and methane dicarboxylic aldehyde (MDA) in DT group were significantly higher than INN group (P<0.05). The five kinds of immunoglobulins levels (IgA, IgD, IgE, IgG and IgM) in DT group were higher than those in INN group (P<0.05). The heart rate (HR) in DT group was lower and mean arterial pressure (MAP) was higher than that in INN group(P<0.05). There was 1 cases of macrosomia, 2 cases of premature delivery in DT group, the adverse pregnancy outcomes was 4.35%(3/69). there was 1 cases of macrosomia, 1 cases of congenital deformity, 1 cases of premature delivery and 1 case of postterm delivery in DT group, the adverse pregnancy outcomes was 5.80%(4/69), with no significant difference between two groups. Conclusion Dexamethasone combined with anesthesia is very effective for delivery of elderly parturient women which shows very good anti-inflammatory and immunoregulation.

2.
Modern Clinical Nursing ; (6): 36-38,39, 2014.
Article in Chinese | WPRIM | ID: wpr-553421

ABSTRACT

Objective To study the effects of peer education on sleep quality in the elderly parturient women.Methods One hundred and twelve elderly parturient women were divided randomly into control and intervention groups,with 56 cases in each group. The patients in control group received routine health education,while the intervention group peer education besides routine health education for 8 weeks. The two groups were compared using Pittsburg sleep quality index(PSQI)and self-rating anxiety scale (SAS).Results After intervention,the two groups were significantly developed in terms of the PSQI and SAS scores compared to post-intervention,respectively(P<0.05). In comparison of the two group,the PSQI and SAS scores in the intervention group were statistically significantly different(P<0.01).Conclusion Peer education can improve the sleep quality of the elderly parturient women and mental status.

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