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Objective@#To determine the relationship between volume of epicardial adipose tissue (EAT) and atrial fibrillation (AF) .@*Methods@#A total of 207 patients who hospitalized in the Department of Cardiology, Nantong University Affiliated Hospital from January 2016 to June 2018 were included in this study. They were divided into two groups, including AF group (n=125) and sinus rhythm group (n=82). The AF group included 80 paroxysmal AF (PAF) and 45 persistent AF (PeAF) patients. Total EAT and left atrial EAT (LA-EAT) volume were measured using 256 rows of multi-slice spiral CT in all patients. Echocardiographic derived left ventricular ejection fraction (LVEF) and left atrial diameter (LAD) were analyzed. Hospholipase A2 and blood lipids were examined in all patients. The baseline data and EAT volume of all groups were compared. The multivariate logistic regression was used to analyze the risk factors related to the occurrence of AF. The correlation between total EAT volume and LA-EAT volume and LAD were analyzed by Pearson correlation.@*Result@#The volume of total EAT in patients with sinus rhythm, AF, PAF and PeAF were (92.2±32.1), (136.0±46.0), (134.2±46.3) and (140.1±52.6)cm3, respectively. The volume of LA-EAT in patients with sinus rhythm, AF, PeAF and PAF were (27.1±7.5), (39.2±19.2), (35.9± 17.0) and (45.1±21.5)cm3, respectively. Total EAT and LA-EAT volume were significantly larger in PAF and PeAF groups than in sinus rhythm group (all P<0.01). The LA-EAT volume was larger in PeAF group than in PAF group (P<0.01), but total EAT volume was similar between two groups (P>0.05). Logistic regression analysis showed that total EAT volume (OR=1.202, 95%CI 1.083-1.334, P=0.001), LA-EAT volume (OR=1.051, 95%CI 1.003-1.101, P=0.037) and LAD (OR=1.019, 95%CI 1.005-1.032, P=0.006) were the independent related factors of AF. Pearson correlation analysis showed that the total EAT volume was positively correlated with LAD (r=0.466, P<0.01) and LA-EAT volume was positively correlated with LAD (r=0.290, P<0.01).@*Conclusion@#The volume of total EAT and LA-EAT measured by 256-row multi-slice spiral CT is significantly correlated with the incidence of AF.
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Objective To evaluate the correlation of epicardial adipose tissue volume (EATV)with coronary plaques in patients with a coronary artery calcium score of zero.Methods 183 patients with a coronary artery calcium score of zero were selected.They were divided into plaque group and control group according to the findings of CT coronary angiography.Independent t test was used to analyze the difference of EATV between two groups.Results ①EATV was significant higher in plaque group than that in control group (P 0.05), while it was significant higher in plaque group than that in control group for male individuals (P <0.05).③EATV was significant higher in plaque group than that in control group for the individuals with age< 50 years (P <0.05 ),meanwhile it was significant higher in plaque group than that in control group in age≥50 years(P <0.05).Conclusion EATV is correlated with coronary plaques in male patients with a coronary artery calcium score of zero while there is no correlation with female patients.EATV is correlated with coronary plaques in different age patients with a coronary artery calcium score of zero.
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Objective To investigate the comparison of volume of epicardium adipose tissue and calcification score on evaluating the degree of coronary artery stenosis(CHD).Methods Two hundred and ten cases with suspected coronary artery disease scanned by the 64 multi slice CT (MSCT) were selected as our subjects.One hundred and forty-five cases were diagnosed non coronary heart disease by with ＜ 50％ coronary artery stenosis by coronary angiography and served as non-CHD group.Other 55 cases were diagnosed as CHD with coronary artery stenosis ≥ 50％ and served as CHD group.The volume of epicardium adipose tissue and calcification score of all cases were calculated with Siemens definition workstation.Results The volume of epicardium adpose tissue and calcification score in patients of CHD group were (117.3 ± 57.6) cm3 and (413.3 ± 670.5) ％,significant different from that of non-CHD group ((100.0 ± 46.5) cm3,(36.2 ± 118.5).The differences were statistically significant (t =2.316,6.564; P ＜ 0.05,P ＜ 0.01).ROC curves showed that the sensitivity and specificity of calcification score were higher than the methods of volume of epicardium adipose tissue in terms of the diagnosis of stenosis and coronary artery disease.Conclusion Calcification score is proved to be a better method of predicting the coronary artery stenosis.