Gorlin Goltz syndrome: a rare case report

Gorlin-Goltz syndrome is uncommon multisystemic disease with an autosomal dominant trait, with complete penetrance and variable expressivity, though sporadic cases have been described. We report a case of 18 years old male patient having features of Gorlin Goltz syndrome. Gorlin-Goltz syndrome is characterized by multiple basal cell nevi or carcinomas, odontogenic keratocysts, palmar and/or plantar pits, calcification of the falx cerebri, and is associated with internal malignancies. It is important to know the major and minor criteria for the diagnosis and early preventive treatment of this syndrome.

Effects of minimally invasive tumor resection under microscope on symptoms improvement, Simpson classification and prognosis in patients with sagittal sinus and falx cerebri meningioma / 中国基层医药

Objective To analyze the effects of minimally invasive tumor resection under microscope on symptoms improvement,Simpson classification and prognosis in patients with sagittal sinus and falx cerebri meningioma.Methods From December 2012 to December 2016,123 patients with parasagittal and falx meningioma in the People 's Hospital of Shanxi Province were randomly divided into two groups according to the digital table.The control group (61 cases) underwent conventional craniotomy,and the study group (62 cases) performed minimally invasive tumor resection.The symptoms improvement,Simpson classification and postoperative recurrence were compared between the two groups.Results The operation time between the two groups had no statistically significant difference (t =1.13,P ＞ 0.05).The intraoperative blood loss in the study group was (119.05 ± 26.94) mL,which was lower than (172.05 ±27.43) mL in the control group (t =10.81,P ＜ 0.01).The postoperative symptoms improvement of movement of limbs (3.22％),epilepsy (4.65 ％),sensory dysfunction (1.61％) in the study group were significantly better than those in the control group (14.75％,31.15％,27.87％) (x2 =5.02,6.34,4.14,all P ＜ 0.05).The Simpson classification of tumor resection rate in the study group was better than that in the control group(x2 =12.23,P ＜0.01).The incidence rates of complications such as epilepsy(0.00％) and intracranial hemorrhage(1.61％),and recurrence rate(0.00％) in the study group were lower than those in the control group(26.23％,27.87％,27.87％)(x2 =4.05,4.14,4.65,all P ＜ 0.05).Conclusion Minimally invasive tumor resection under the microscope can effectively improve clinical symptoms of patients with sagittal sinus and falx cerebri meningioma,which can improve tumor resection rate,effectively reduce the incidence of postoperative complications and recurrence rate.

Multifocal Calcifications of the Falx Cerebri and Dura Presenting as Hot Spots in the Skull on Bone Scintigraphy / 핵의학분자영상

A 49-year-old woman with invasive ductal carcinoma of the right breast underwent Tc-99m MDP bone scintigraphy for an evaluation of skeletal metastases. Multiple focal hot spots in the midline and left frontoparietal skull region were observed. The plain radiographs revealed the typical findings of the calcification of the falx cerebri and dura. These findings might be mistaken for metastases of the skull in cancer patients. Therefore, a radiographic correlation is essential when multifocal hot spots in the skull are observed in cancer patients.

Cavernous Angioma in the Falx Cerebri: A Case Report

Intracranial cavernous angiomas are benign vascular malformations and can be divided into intra-axial and extra-axial lesions. Extra-axial cavernous angiomas are relatively rare and usually arise in relation to the dura mater and mimick meningiomas. We report a case of cavernous angioma that occured in the falx cerebri of a 22-yr-old female patient with the special focus on neuroradiologic findings. This is the fourth case of cavernous angioma in the falx cerebri reported in the literature to our knowledge.

Falcine Mesenchmal Chondrosarcoma

We experienced a case of falcine mesenchymal chondrosarcoma in a 22-year-old pregnant woman. Cartilage cell tumors within the cranium are very rare, only less than 0.2% of all intracranial tumors. Because a few examples of mesenchymal chondrosarcoma in this locttion have been reported, we reviewed previous reports cases, to determine the natural history of intracranial chondrosarcomas. The distinguishing features of this rare tumor are compared with previous cases of itracranial tumors derived from cartilage.

A Case of Oligodendroglioma Attached to the Leptomeninges and Falx Cerebri

We have experienced a case of oligodendroglioma which was similar to a falx meningioma. The oligodendroglioma arose in the medial surface(paracentral lobule) of the right frontal lobe and firmly attached to the falx cerebri. The tumor was found in early life(16 year old) and it had no roentgenographic calcification. So histological confirmation was possible after the operation. We report this uncommon oligodendroglioma with a review of literatures.