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Objective:To understand the application status of precursor drugs in the outpatients of our hospital. Methods:Totally 12 kinds of precursor drugs were included in the management. The data of prescriptions in HIS were collected from July 1 to September 30 in 2015. The defined daily dose (DDD), frequency of drug use (DDDs), drug utilization index (DUI) and the other parameters were calculated and the influencing factors were analyzed by the Pareto method. Results: Among the twelve precursor drugs, DUI of seven kinds was less than or equal to 1. Paracetamol tablets, pseudoephedrine hydrochloride tablets, dextromethorphan hydrobromide and chlorphenamine maleate tablets, nicergoline tablets and compound dextromethorphan hydrobromide tablets II displayed lower DUI, indicating their clinic application was more reasonable. Conclusion:The data showed that the use of precursor drugs in our hospital is basically reasonable.
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Objective To evaluate opioids utilization of cancer ached inpatients in the integrative traditional Chinese and western medicine hospital and provide suggestion for the rational utilization of opioids .Method DDDs ,DUI ,the distribution of cancer pain ,pain scores of the discharged patients and the utility of opioids were evaluated and analyzed by retrieving the medi-cal records from January in 2013 to December in 2014 .Results 292 medical records were selected and analyzed .Among them , 89 patients′pain score≥3 .The top opioids of DDDs were sufentanil citrate injection and fentanyl derivatives ,which is the main medication in treating the cancer pain patients .And the irrationaluseof fentanyl transdermal system was a common phenomenon among different departments .Conclusion Theutilization of opioids was basically rational ,but there still had some deficiencies . The intervention and management of narcotic drugs should be strengthened and deepened .
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OBJECTIVE:To provide a reference for clinical use of anti-tumor adjuvant drugs as is reasonable,effective and economical. METHODS:By retrospective investigation and analysis,the utilization of anti-tumor adjuvant drugs in the oncology department of our hospital during 2010 and 2013 was analyzed statistically in respect of the type,dosage form,consumption amount,DDDs,DDC,DUI etc. RESULTS:The anti-tumor adjuvant drugs in our hospital were dominated by injections,especial-ly domestic drugs,the consumption amount of which accounted for 80% of the total consumption amount of anti-tumor adjuvant drugs each year. The anti-tumor adjuvant drugs were mainly used for symptomatic treatment of various adverse reactions. Drug syn-chronization was relatively good each year,however,excessive use of individual drugs existed. CONCLUSIONS:Anti-tumor adju-vant drugs have relatively better synchronism in the drugs quantities and medication number. However,individual drugs have exces-sive use and other irrational use.
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Objective To probe into the application feature and use tendency of traditional Chinese medicine (TCM) injections in our hospital;To evaluate rational drug use and provide reference for related researches. Methods TCM injections in our hospital during 2010-2012 were analyzed by employing the analytic method of defined daily dose, with a purpose to evaluate frequency of drug use and rationality of medication expenses. Results From 2010 to 2012, drug possession rate of TCM injections in our hospital was 4.07%-4.47%;the amount of medication accounted for 10.50%to 12.69%of the amount of all drugs;the annual growth rate increased significantly, among which TCM injections used for removing blood stasis took the lead;frequency of drug use rose annually;medication synchrony in 3 years indicated that daily expensesof Shenkang Injection, Aidi Injection, salvianolateinjection, safflor yellow sodium chloride injection and other TCM injections were on the high side. Conclusion From 2010 to 2012, TCM injections in the clinical application in our hospital were of relatively high frequency, and the TCM injections used for removing blood stasis took the lead. Daily expenses of TCM injections drugs were on the high side and there may be unreasonable application.
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Objective:To evaluate the current situation and the developing trend of 5-HT3 receptor antagonists used in 25 hospital of Wuhan during the period of 2003～2005 in order to provide reference for clinical doctors and pharmacists. Method:The 5-HT3 receptor antagonists were statistically analyzed in respect to the purchase sum of money,DDDs and daily costs. Result:During the 3 years, purchase sum of money of 5-HT3 receptor antagonists were yearly increasing. The share of the market of domestic drugs showed an increasing tendency,while the imported drugs decreased year by year. Granisetron, ondansetron and tropisetron were much more frequently used than others. Conclusion:The market of the oral agents of 5-HT3 receptor antagonists will further expand in China.
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OBJECTIVE:To discuss the influence of drug price reduction and regulation of purchase on the use of anti-infectives in our hospital.METHODS:The use of anti-infectives in5times of drug price reduction was retrospective anal?ysed.RESULTS:The proportion of the sum of money for consumption of anti-infectives in the total sum for drug consumption dropped year by year but the total DDDc of anti-infectives increased year by year.The DDDs and the total DDDc of all kinds of anti-infectives showed different characteristics.CONCLUSION:The macroscopic price reduction for anti-infectives posi?tively affects the rational use of anti-infectives,yet the effect is limited.Microcosmic regulation of purchase offers an indis?pensable effect.
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OBJECTIVE:To make out the current situation and trend of antibiotics used in hospitals of Shanghai and to make objective evaluation METHODS:To investigate antibiotics used in 47 hospitals of Shanghai during the period 2000～2002 in respect to the sum of money of consumption,kinds of drugs,frequency of use and DDDs RESULTS:During the period 2000～2002,the average annual consumption of antibiotics accounted for 21 24% of the sum of money for total consumption of drugs and droped with an average rate of 1 9% In which,antibiotics for injection rised with a rate of 10 59% successively,and oral antibiotics decreased with a rate of 10 82% In amount of consumption,Ceftriaxone,Cefuroxime and Ceftazidime occupied the front places of antibiotics for injection And the corresponding order of oral antibiotics were Cefaclor,Cefradine and Amoxicillin CONCLUSION:The consumption of cephalosporins was the highest in the order of sum of money of antibiotics The market prospects of antibiotics for injection will be wide and bright
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OBJECTIVE:To investigate the situation and developing trend of the use of narcotics METHODS:The data of narcotics used in our hospital in 2000～2002 were collected from HIS System and analyzed RESULTS:The sum of money of narcotics was increasing year by year,especially for morphine preparation;The use of Durogesic and MS Contin for the pain control of cancer occupied the first and second places in frequency,but the amount of use of pethidine injection was constantly high CONCLUSION:Irrational drug-use for the pain control of cancer still existed
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OBJECTIVE:To keep abreast of the situation and trend of patent Chinese materia medica used in our hospital METHODS:To collect the amount of consumption and sum of money of patent Chinese materia medica used in our hospital in 2000～2001 and to analyse the frequency of drug use RESULTS:The consumption of part of drugs decreased by 7%～17% Those drugs with increasing tendency in consumption kept stable in increase The DDDs of compound red sage tablet increased by 22% CONCLUSION:For supply and management of patent Chinese materia medica,it is very important to analyse and understand the sum of money of consumption and frequency of drug use
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AIM: To investigate cl in ical usage of drugs for respiratory system diseases. METHODS: Th e in-hospital records from November 2001 to February 2002 were investigated in a hospital. The usage and utilization of the drugs were analyzed with DDDs. Drug interactions were evaluated with a software (Reasonable Medication System). RESULTS: The frequency of use of antimicrobial accounted for 35% in total. The other two kinds were anti-asthma drugs and the removing fever of re ady-made traditional Chinese medicine. Some unreasonable interactions were foun d in this investigation. CONCLUSION: In the hospital, the usage of drugs for respiratory system diseases is rational on the whole, but drugs int eraction should not been neglected.
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OBJECTIVE:To understand the situation of drugs used in this hospital.METHODS:To collect the amount and sum of money of drugs consumed in this hospital in the first halves of 1999,2000 and 2001 and to analyse the frequency of antibiotics used.RESULTS&CONCLUSION:The consumption of antiinfectives,herbal preparations and other commonly-used drugs was in the ratio 2∶4∶4.The use of antibiotics was on the whole rational.
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OBJECTIVE:To provide the information of drug-use in SARS for reference.METHODS:123medical charts of inpatients from April20,2003to May31,2003were analyzed,including the kinds and the cost of drugs that have been used.The frequency of drug-use and DUI were calculated from DDD of drugs.The kinds and costs of drugs used for930employees were also analyzed.The drug cost per employee was compared with that per inpatient.RESULTS:4kinds of drugs were abused.The dosage and usage of the other drugs were appropriate.17kinds of main drugs and2kinds of decoctions prepared by our hospital have been used to inpatients,which costed559440yuans in all,4548.29yuans per inpatient.While14kinds of drugs and one kind of decoction against SARS were used to employees,which costed about500000yuans in all,537.6yuans per employee.CONCLUSION:SARS is still an unknown disease.Although most of the dosage and usage of drugs were appropriate in prevention and treatment of SARS,whether the drugs should be used or not is open to question.
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OBJECTIVE:To get a clear idea about the situation of application of hypolipemic agents in hospitals of Shanghai so as to provide information for departments of production,sale and consumption METHODS:The kind,amount,sum of money and DDDs of hypolipemic agents,used in 47 hospitals in Shanghai during the period 1999～2001,were analysed RESULTS:Vastatin,Fibrate and Chinese materia medica were the most commonly used drugs;Simvastatin,Zhibituo and Fenofibrate occupied the front places in amount of consumption;The sales volume of Zocor(Simvastatin)Pravachol and Xuezhikang was at the top of list;Simvastatin,Fluvastatin,Xuezhikang and Fenofibrate revealed increasing tendency and Gemfibrozil,Zhibituo,Duoxikang and Chondroitine showed decreasing tendency in clinical use CONCLUSION:The market prospects of hypolipemic agents will be wide and bright
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OBJECTIVE:To investigate the current situation and developing trend of the use of antipsychotics.METHODS:The data of antipsychotics in Analysis System of Drug-use in the Hospitals of the Yangtze River Valley,reported by Hangzhou,Shanghai,Nanjing,Wuhan,Chengdu and Chongqing during the period 1997～2001,were analysed by using DDD as index.RESULTS:The sum of money and frequency of use of the antipsychotics were increasing year by year;The first generation antipsychotics still occupied the marketing predominance;The use of the second generation antipsychotics assumed an increasing tendency year by year.CONCLUSION:The marketing of antipsychotics will further expand in China and the pharmaceutical factories should strengthen the development of new antipsychotics.