ABSTRACT
AIM: To explore the results of fundus screening in 5 307 newborns and the related factors of fundus diseases.METHODS: A total of 5 307 newborns who underwent fundus screening in our ophthalmology department from January to December 2022 were selected. RetCam III system was used for fundus examination, and abnormal fundus conditions were recorded. The influencing factors of retinal hemorrhage in full-term infants and retinopathy of prematurity(ROP)in preterm infants were analyzed.RESULTS: The incidence of ocular abnormalities in newborns was 27.17%, with the highest incidence of retinal hemorrhage(61.23%), followed by retinal exudation(22.95%), ROP and ROP like retinopathy(10.68%). The incidence of morning glory syndrome(0.21%), albino fundus(0.21%), and permanent fetal vasculature(PFV; 0.28%)was lower. The incidence of eye abnormalities in full-term infants was lower than that in preterm infants(26.30% vs 30.08%, P<0.05), and the incidence of retinal hemorrhage and exudation in full-term infants was higher than that in preterm infants(P<0.05). The incidence of ROP and ROP like retinopathy in preterm infants was higher than that in full-term infants(P<0.05). Natural delivery is a risk factor for retinal hemorrhage in full-term infants(P<0.05). Fetal age(32-34, 30-31 wk), birth weight(1 500-2 499, <1 500 g), milk powder feeding, and oxygen inhalation are risk factors for ROP in premature infants(all P<0.05).CONCLUSION: The incidence of eye abnormalities in newborns at our hospital is relatively high, and early detection of eye abnormalities in newborns can be achieved through fundus screening.
ABSTRACT
@#AIM:To understand the basic conditions of neonatal fundus lesions and analyze the influencing factors of retinal hemorrhage.<p>METHODS: Totally 289 neonates from our hospital in the department of obstetric ward and neonatal intensive care unit from January 1, 2016 to May 31, 2018 were screened for fundus oculi disease by Retcam Ⅲ. The following information were collected such as gender, gestational age, history of asphyxia, maternal pregnancy and delivery way.<p>RESULTS: Among the 289 infants, there were 97 premature infants and 192 term infants. Sixty-four(22.1%)were detected with fundus lesions. Among which, 34(11.8%)were detected with retinal hemorrhage and 23(8.0%)retinopathy of prematurity. Single factor analysis showed that the rate of retinal hemorrhage in premature infants was higher than term(<i>P</i><0.05). The rate of retinal hemorrhage in neonates with perineal delivery was higher than cesarean section(<i>P</i><0.05). The rate of retinal hemorrhage in neonates with a history of asphyxiation was higher than that without(<i>P</i><0.05). The rate of retinal hemorrhage in neonates with high blood pressure during pregnancy was higher than that without(<i>P</i><0.05). After adjusting for the effects of risk factors, preterm infants, perineal births, history of asphyxiation, and high blood pressure during pregnancy were the high risk factors for neonatal retinal hemorrhage(<i>P</i><0.05).<p>CONCLUSION: The incidence of neonatal retinal hemorrhage is relatively high, which is related to factors such as gestational age, mode of delivery, history of asphyxia and history of maternal pregnancy hypertension.