Clinical Evaluation of Serum and Urinary Carcinoembryonic Antigen in Genitourinary tumor / 대한비뇨기과학회지

Carcinoembryonic antigen(CEA) was measured by the enzyme immunoassay(EIA) technique in the serum and urine of 25 patients with non-tumor disease and 68 patients with several types of genitourinary tumor at the Department of Urology, Kyungpook National University Hospital during period from January 1982 to May, 1984. The results were as follows : 1. Mean serum and urine CEA levels in 24 normal controls were 3.97 ng/ml and 9.56 ng/ml. The upper limit of ""Normal"" for CEA levels was fixed at 2 standard deviation above the mean of normal controls. Therefore, we accept 9ng/ml and 23 ng/ml as the upper limit of normal for serum and urine 2. Mean serum and urine CEA levels in 21 patients with urinary infection were 5.70 ng/ ml and 21.14ng/ ml and incidence of positive results in serum and urine were 9.5% and 33%. Mean serum and urine CEA. levels in 68 patients with G-U tumor were 11.08ng/ ml and 49.12 ng/ ml and incidence of positive results in serum and urine were 32% and 34% 3. Mean serum and urine CEA levels in bladder ca were 13.78 ng/ ml and 60.43 ng/ ml being the highest elevation in G-U tumor, 12.74 ng/ ml and 53.60 ng/ ml in renal cell ca and 7.98 ng/ ml and 44.40ng/ ml in ureteral ca. Incidence of positive results of serum and urine in bladder ca were 38% and 38%, 23% and 38% in renal cell ca and 33% and 40% in ureteral ca. 4. Mean CEA levels and incidence of positive results in urine were correlated with the stage and grade of bladder ca. 5. Preoperative and postoperative serum and urine CEA measurements were useful in determining the completeness of tumor resection in patients with G-U tumor. However, in case of ileal conduit with cystectomy or incomplete resection of tumor mass, serum and urine CEA levels were increased postoperatively.

A Clinical Observation on Tumors of the Genitourinary Tract / 대한비뇨기과학회지

A clinical observation was made on patients with the tumors of the genitourinary tract, who were admitted to the Department of Urology, Kyungpook National University Hospital during 10 years period from January 1970 to December 1979. Out of 1606 total hospital admissions. 284 were due to the tumors of the genitourinary tract, giving rate of 17.68%, sex ratio, male to female, was 6.89:1 The most frequently involved age group was the 7th decade, being 31% of total, followed by the 6th decade (22%). About 85.21% was seen at age of 40 and over. Prostate was the most commonly involved organ comprising 122 (42.96%) out of 284 cases of the tumors of the genitourinary tract, followed in frequency by bladder in 77 (27.11%), kidney in 40 (14.08%), and penis in 24 (8.45%). The tumors were benign in 123 and malignant in 161, giving ratio of benign to malignant approximately 1:1.3. The most common type among benign group was B.P.H. and among malignant type, bladder carcinoma. Pathologic diagnosis was performed on 174 cases. Out of these, 52 were diagnosed as transitional cell carcinoma of bladder, followed in frequency by B.P.H. in 36 and squamous cell carcinoma of penis in 16.

The Value of Urine Cytology on the Genitourinary Tumors / 대한비뇨기과학회지

The cytologic examination of the urine is very simple and inexpensive procedure for the detection and follow-up of the genitourinary tumors, and worthy as a mass screening test. To observe the accuracy of the cytologic examination on the genitourinary tumors, we have evaluated the results of the examination which were performed at the Department of Urology, Seoul National University Hospital during the period from January, 1977 to September, 1978. Two hundred fifteen patients were subjected to this study. Of which 108 cases were known as to have genitourinary tumors clinicopathologically. 107 cases who did not have genitourinary tumors were also included in to compare with the tumor patients. Following results were obtained according to the various analysis.

Clinical Observation on Tumors of the Genito-urinary Tract / 대한비뇨기과학회지

A clinical observation was made on 80 cases of genito-urinary tract tumors of the in-patients in the Department of Urology, Chungnam University Hospital during 3.5 years, from January 1974 to June 1977. The following results were obtained. 1. During this period, of 348 cases hospitalized, 80 cases (76 males. 4 females) had tumors of the genito-urinary tracts, giving a rate of 22.9%.2. In 80 cases of genito-urinary tract tumors, 46 cases (57.5%) were benign tumors and 32 cases (40.0%) were malignant tumors. Of the benign tumors, B.P.H. was the most common tumors and of the malignant tumors, bladder cancer was the most common tumors. 3. The majority of the patients(87.5%) were distributed over age of 40 years, showing highest incidence at 60-69 years. 4. In 80 cases of the genito-urinary tract tumors, 46 cases(57.5%) were prostatic, 17 cases (21.2%) vesical, 9 cases(11.2%) renal, each 3 cases(3.7%) penile and testicular, and 2 cases (2.5%) urethral. 5. Histopsthologically, B.P.H. was observed in 49.3% of all operated tumors, transitional cell carcinoma of bladder in 16.9% and adenocarcinoma of prostate in 5.7%. 6. Operation was performed in 71 cases (88.7%).