Clinicopathological study of parasitic lesions of the eye and ocular adnexa in a tertiary care ophthalmic center in South India

Purpose: To study clinical and pathological features of parasitic lesions in the ocular adnexa in a tertiary care ophthalmic center in south India. Methods: 43 cases of ocular parasitosis were analysed clinically and correlated with the pathological findings (gross morphology and histopathology) over a period of five years (2015–2020). Results: Among the 43 cases, the age group ranged from 9 months to 78 years (mean age of 41.6 years). Female patients were more common than male patients, with a percentage of 63% (27) and 37% (16) respectively. Cystic lesion in the lid or orbit was seen in 23 cases (53.4%); solid mass lesions were seen in 17 cases (39.5%); subconjunctival worms in three cases; and subretinal parasite in one. Gross examination and histopathologic study showed Dirofilaria in 23 cases (53.5%), followed by Cysticercus in six cases (14%) and Microfilariae in four cases (9.3%). Exact species identification was not possible in ten cases (23.25%). Correlation between the type of lesion and type of inflammatory cells with the specific parasite was done. Conclusion: Our study showed that important clinicopathological correlations can be made from the parasitic lesions in the eye and adnexa, which can aid in definitive diagnosis and prompt identification of the parasite for patient management

Clear Cell Renal Cell Carcinoma with Intratumoral Granulomatous Reaction: A Case Report and Review of the Literature

Granulomatous reaction associated with clear cell renal cell carcinoma (CCRCC) is a rare finding, and only a few cases have been described in the literature. It is postulated to occur due to cancer-related antigenic factors such as cancer cells themselves or soluble tumor antigens shed into the blood. Herein, we describe a case of a 56-year-old male patient diagnosed with CCRCC with intratumoral granulomatous inflammation.

Haga su diagnóstico / Do your diagnostic

Presentamos el caso de un niño con numerosas placas tumorales discrómicas bien definidas, algunas atróficas, otras levantadas, cubiertas por formaciones escamo-costrosas, indoloras, localizadas en extremidad inferior derecha, de curso lentamente progresivo. No se encuentran otros hallazgos clínicos acompañantes de importancia. El diagnóstico de certeza se efectúo mediante estudio de imagen e histopatológico; el tratamiento consistió en extirpación quirúrgica a intervalos irregulares.

An eleven-year old child with multiple depressed and raised skin pigmented tumors and plaques, with adherent desquamation and crusts on their skin suface was located in his right lower extremity. There are not any other clinical manifestation of interest. Diagnostic approach was based on radiological and pathology examinations. Surgical treatment was the suitable option.

A Case of Granulomatous Reactions to a Permanent Red Tattoo / 대한피부과학회지

Complications of tattooing include infection, hypersensitivity reaction and scarring. Hypersensitivity reaction is most common. Components of the red pigments used in some tattoos are the most commonly known cause of delayed tattoo reactions. A 22-year-old woman presented with 3~4 mm sized, well-defined indurated scaly plaques confined to red portion of rose tattoo on the dorsal surface of the left foot. She complained of mild pain and severe pruritus on the lesion. Histopathologic examination showed granulomatous reactions from a permanent red tattoo. The patient was transferred to the plastic surgery for surgical intervention. We document an unusual tattoo reaction presenting as plaques from red portion of tattoo, which on histopathologic examination showed granulomatous reaction.

Cerebellar Schistosomiasis: Case Report

The central nervous system involvement of Schistosomiasis is rarely reported in the literatures. The authors report a case of cerebellar Schistosomiasis. A 40-year-old man presented to our hospital with a one year history of dizziness and gait disturbance. The computerized tomography and MRI of the brain and spinal cord showed tumoral form of mass on cerebellar vermis and roof of the fourth ventricle. The histological study of the partially excised cerebellar mass demonstrated granulomatous reaction around Schistosoma mansoni eggs. After operation, praziquantel was used for 7 days(60 mg/kg/day) drally. This is the first case report of central nervous system Schistosomiasis in Korea.