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Human cysticercosis is caused by cysticercus cellulosae, larvae of a tapeworm, taenia solium. Cysticercois can involve any tissue in the body even it has maximum tendency towards neural tissue. The most common affected sites are central nervous system, subcutaneous tissue, eyes and muscles. An isolated case of intramuscular cysticercosis is a rare presentation. Here we present the case of a 35 year old female with a swelling on the posterolateral aspect of right arm and was diagnosed as myocysticercosis which was abuting to the extensor muscle that is triceps muscle on high resolution ultrasound and ct scan and it was managed by antihelminthic medications followed by surgical excision.
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Medial knee joint pain is a common problem in the field of orthopedics. In these patients, a high resolution ultrasound examination can reveal medial collateral ligament (MCL) bursitis, meniscal cyst, degeneration changes to the MCL and meniscal protrusion etc. Prolotherapy is effective in these patients. The author performed prolotherapy for MCL bursitis of the knee joint, and confirmed the disappearance of the bursitis using high resolution ultrasound.
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Humans , Bursitis , Collateral Ligaments , Knee Joint , Knee , Orthopedics , UltrasonographyABSTRACT
To evaluate the cardiac function of cecal ligation and puncture (CLP) induced sepsis rats with high-resolution ultrasound. Methods According to the method of random number table, 48 adult male Sprague-Dawley (SD) rats were randomly divided into normal control group and sepsis 6, 12, 24, 30, 48 hours groups, with 8 rats in each group. The sepsis model was produced by CLP, and the rats in the normal control group were only anesthetized and resuscitated. The general situation after modeling in each group was observed, and the left ventricular function was assessed by high-resolution echocardiography at all the time points. The abdominal aorta blood of rats was collected, and the serum levels of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and MB isoenzyme of creatine kinase (CK-MB) were determined by enzyme-linked immunosorbent assay (ELISA). The myocardial tissue was harvested, and the pathological changes in myocardial tissue were observed by hematoxylin-eosin (HE) staining. Results The rats challenged to CLP displayed symptoms of sepsis, such as depression, ruffled fur, decreased diet and activity, and the symptoms became more obvious with the extension of time. High-resolution echocardiography could clearly show the structure of left ventricle in each group and obtain satisfactory M-mode echocardiography of left ventricle. The heart rate (HR) of rats in all sepsis groups was elevated with the increase in model time as measured by high-resolution ultrasound, and it was significantly higher than that in the normal control group at 12, 24, 30 hours (bpm: 359.66±23.33, 361.35±12.85, 392.67±11.33 vs. 306.24±29.79, all P < 0.05). Stroke volume (SV) and cardiac output (CO) in sepsis rats were decreased with the increase in model time, while left ventricular ejection fraction (LVEF) and left ventricular fractional shortening (LVFS) were increased first and then decreased, and SV and LVEF in sepsis 48 hours group were significantly lower than those in the normal control group [SV (μL): 78.43±17.52 vs. 122.61±15.88, LVEF: 0.763±0.018 vs. 0.902±0.011, both P < 0.05]. Left ventricular weight (LVW) in all sepsis groups was increased to different degrees as compared with that in the normal control group, as well as the left ventricular anterior and posterior wall thickness increased in diastole and systole. Compared with the normal control group, the left ventricular posterior wall thickness was increased significantly at the end of diastolic and systolic period in the sepsis 12 hours group, and the left ventricular anterior wall thickness was also increased significantly at the end of diastolic period in the sepsis 48 hours group. The serum levels of TNF-α, IL-1β and CK-MB in sepsis rats were increased first and then decreased with the extension of model making time. The above parameters in the sepsis 48 hours group were still significantly higher than those in the normal control group [TNF-α (ng/L): 61.59±3.99 vs. 16.87±4.89, IL-1β (ng/L):255.03±13.23 vs. 119.59±10.43, CK-MB (μg/L): 1.27±0.15 vs. 0.52±0.15, all P < 0.05]. HE staining showed that the myocardial striations of the rats in the normal control group were clear and complete, with normal morphology and orderly arrangement of cardiac cells. However in the sepsis groups, myocardial cells were swollen, ruptured and necrotic, and inflammatory cells were infiltrated, with myocardial fibers ruptured and necrosis dissolved, and the above pathological manifestations gradually increased with the extension of the model making time. Conclusion High-resolution ultrasound can evaluate the cardiac function of CLP induced sepsis rat model more comprehensive, and the consequence of evaluation index is consistent with the expression level of myocardial enzyme and histopathologic manifestations.
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Objective@#To evaluate the cardiac function of cecal ligation and puncture (CLP) induced sepsis rats with high-resolution ultrasound.@*Methods@#According to the method of random number table, 48 adult male Sprague-Dawley (SD) rats were randomly divided into normal control group and sepsis 6, 12, 24, 30, 48 hours groups, with 8 rats in each group. The sepsis model was produced by CLP, and the rats in the normal control group were only anesthetized and resuscitated. The general situation after modeling in each group was observed, and the left ventricular function was assessed by high-resolution echocardiography at all the time points. The abdominal aorta blood of rats was collected, and the serum levels of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and MB isoenzyme of creatine kinase (CK-MB) were determined by enzyme-linked immunosorbent assay (ELISA). The myocardial tissue was harvested, and the pathological changes in myocardial tissue were observed by hematoxylin-eosin (HE) staining.@*Results@#The rats challenged to CLP displayed symptoms of sepsis, such as depression, ruffled fur, decreased diet and activity, and the symptoms became more obvious with the extension of time. High-resolution echocardiography could clearly show the structure of left ventricle in each group and obtain satisfactory M-mode echocardiography of left ventricle. The heart rate (HR) of rats in all sepsis groups was elevated with the increase in model time as measured by high-resolution ultrasound, and it was significantly higher than that in the normal control group at 12, 24, 30 hours (bpm: 359.66±23.33, 361.35±12.85, 392.67±11.33 vs. 306.24±29.79, all P < 0.05). Stroke volume (SV) and cardiac output (CO) in sepsis rats were decreased with the increase in model time, while left ventricular ejection fraction (LVEF) and left ventricular fractional shortening (LVFS) were increased first and then decreased, and SV and LVEF in sepsis 48 hours group were significantly lower than those in the normal control group [SV (μL): 78.43±17.52 vs. 122.61±15.88, LVEF: 0.763±0.018 vs. 0.902±0.011, both P < 0.05]. Left ventricular weight (LVW) in all sepsis groups was increased to different degrees as compared with that in the normal control group, as well as the left ventricular anterior and posterior wall thickness increased in diastole and systole. Compared with the normal control group, the left ventricular posterior wall thickness was increased significantly at the end of diastolic and systolic period in the sepsis 12 hours group, and the left ventricular anterior wall thickness was also increased significantly at the end of diastolic period in the sepsis 48 hours group. The serum levels of TNF-α, IL-1β and CK-MB in sepsis rats were increased first and then decreased with the extension of model making time. The above parameters in the sepsis 48 hours group were still significantly higher than those in the normal control group [TNF-α (ng/L): 61.59±3.99 vs. 16.87±4.89, IL-1β (ng/L): 255.03±13.23 vs. 119.59±10.43, CK-MB (μg/L): 1.27±0.15 vs. 0.52±0.15, all P < 0.05]. HE staining showed that the myocardial striations of the rats in the normal control group were clear and complete, with normal morphology and orderly arrangement of cardiac cells. However in the sepsis groups, myocardial cells were swollen, ruptured and necrotic, and inflammatory cells were infiltrated, with myocardial fibers ruptured and necrosis dissolved, and the above pathological manifestations gradually increased with the extension of the model making time.@*Conclusion@#High-resolution ultrasound can evaluate the cardiac function of CLP induced sepsis rat model more comprehensive, and the consequence of evaluation index is consistent with the expression level of myocardial enzyme and histopathologic manifestations.
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Background: Cysticercosis is one of the common infectious disease, the extraneural tissues are usually involved synchronously or metachronously with the brain in this disease. Isolated infestation of soft tissue and muscle in the absence of neural involvement is more common than previously known. High resolution ultrasonography has evolved now as an investigation of choice with proven sonological patterns of soft tissue cysticercosis which has reduced the need for invasive interventions. Methods: Prospective evaluation of total 9 cases of extraneural cysticercosis over a period of 6 months at Prakash institute of Medical Sciences and Research. HRUSG analysis of 9 cases was done to evaluate and classify the various classic sonomorphological features of isolated cysticercosis involving soft tissue and muscles. FNAC was done only in 3 cases. Results: Around 9 patients were selected on the basis of inclusion and exclusion criteria. Among 9 cases, 5 were male and 4 were female patients. Three individuals were vegetarian and five were non vegetarian. Mean age was 35 years. All cases were diagnosed on HRUSG. Intramuscular lesion was identified in 7 cases and 2 cases had subcutaneous involvement with anterior abdominal wall in muscular plane as the commonest site in three patients. FNAC was done in 3 cases confirming the cysticercosis and was treated surgically. Conclusions: With the advent of high resolution ultrasonography and increased clinical awareness of the isolated soft tissue-intramuscular cysticercosis especially in endemic zone, a more conservative non-invasive approach can be applied both in diagnosis and treatment of these isolated cases of cysticercosis.
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Background: Cysticercosis is one of the common disease seen in developing countries. In this disease, the extraneural tissues are usually involved synchronously or metachronously with the brain. Isolated infestation of soft tissue and muscle in the absence of neural involvement is more common than previously thought. High resolution ultrasonography has evolved now as an investigation of choice with proven sonological patterns of soft tissue cysticercosis which can entirely negate the need for invasive interventions. Methods: Prospective evaluation of total 8 cases of extraneural cysticercosis over a period of 4 months at Rama Medical College, Hospital & Research Centre, Hapur. HRUSG analysis of 8 cases was done to evaluate and classify the various classic sonomorphological features of isolated cysticercosis involving soft tissue and muscles. FNAC was done only in 3 cases. Results: Around 8 patients were selected on the basis of inclusion and exclusion criteria. Among 8 cases, 3 were male and 5 were female patients. Three individuals were vegetarian and five were non vegetarian. Mean age was 35 years. All cases were diagnosed on HRUSG. Intramuscular lesion was identified in 6 cases and 2 cases had subcutaneous involvement with anterior abdominal wall in the muscular plane as the commonest site in three patients. FNAC was done in 3 cases confirming the cysticercosis and was treated surgically. Conclusion: With the advent of high resolution ultrasonography and increased clinical awareness of the isolated soft tissue-intramuscular cysticercosis especially in endemic zone, a more conservative noninvasive approach can be applied both in diagnosis and treatment of these isolated cases of cysticercosis.
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Objective To evaluate the clinical value of ultrasound in evaluating the wrist nerve stem.Methods The examination of the high-resolution ultrasound about normal median nerve,ulnar nerve,radial nerve in the wrist on 100 normal volunteers,the courser,shape and sonographic appearance of the nerve stem were observed,and the vertical and horizontal diameter and the area of cross-section were measured.Results (1)Ultrasound clearly showed the nerve stem arranged and organization structures around it.(2) Ultrasound entirely measured the vertical and horizontal sections of normal median nerve,ulnar nerve,radial nerve in the wrist,besides it measured various diameters and the cross-section area.By comparing the vertical diameter of MN and RN between left hand and right hand of the same sexuality,the difference had no statistical significance (P＞0.05).By comparing the various diameters of UN between left hand and right hand of females,the difference had no statistical significance (P＞0.05) By comparing the vertical diameter between left hand and right hand of male,the difference had statistical significance (P＜0.05).To compare the vertical diameter of MN,RN and UN between male and females on the same side,the difference had statistical significance (P＜0.05).To compare the CSA of MN,RN and UN between left hand and right hand of the same sexiuality,the diffevence had no statistical significance (P＞0.05);By comparing the CSA of MN,RN and UN between male and females on the same side,the diffevence had statistical significance (P＜0.05).Median nerve cross-sectional area (CSA) and weight correlation was statistically significant (P ＜ 0.05) in a straight line,no statistically significant correlation was found between age and height (P＞ 0.05).(3) High resolution ultrasound clearly showed the neural surrounding adjacent to the organizational structure,and in line with gross anatomy section.Conclusion Ultraound has a clinical evalution value for examing the wrist nerve
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Background and purpose:During recent years, the incidence of papillary thyroid micro-carcinoma (PTMC) has increased year by year. There are many differences in its diagnosis and treatment. This research investigated and summarized the clinical diagnosis and treatment of thyroid papillary carcinoma by means of analyzing the patients’ data.Methods:Sixty-one cases underwent high resolution ultrasound examination before operation, and the accuracy rate was 86.9%. All patients underwent surgical treatment. Thirty-nine patients had thyroid lobectomy and ipsilateral central lymph node dissection (CLND), 11 underwent concurrent partial thyroidectomy, 22 had total thyroidectomy and bilateral central lymph node dissection and 5 underwent concurrent cervical lymph node dissection. The incidences of central and cervical lymph node metastasis were 44.3% and 8.2%, respectively. Univariate analysis showed that the risk factors for central lymph node metastasis were age <45 years, multifocality, tumor location near or across the midline, tumor diameter≥5 mm. The rates of central lymph node metastasis were 66.7%, 60.7%, 66.7% and 53.8, respectively.Conclusion:High resolution ultrasound examination has a high sensitivity for the detection of PTMC. It is important to implement standardized and individualized treatment plan to the patients with PTMC.
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Introducción: la enfermedad aterosclerótica y sus complicaciones constituyen la causa más frecuente de muerte en el mundo. Un análisis de la relación entre parámetros estructurales y mecánicos de las placas de ateroma carotídea (PAC) es mandatorio a la hora de aumentar nuestros conocimientos en torno a los mecanismos que favorecerían la fatiga mecánica del material de la placa y su complicación. Objetivos: analizar la distensibilidad carotídea en sujetos sanos y con PAC según su composición estructural. Métodos: se estudiaron 100 sujetos asintomáticos con PAC (n=36) y sin PAC (n=64). Se clasificaron las PAC según la mediana de niveles de grises y mapeo por color en lipídicas (L), fibrolipídicas (FL) y fibrosas/calcificadas (FC). Se combinó ultrasonido modo-B con tonometría de aplanamiento y se cuantificó la distensibilidad a lo largo del eje longitudinal en cinco sectores a nivel de la PAC y de la arteria carótida normal. Resultados: se clasificaron 71 PAC (35 L, 16 FL y 20 FC), todas se encontraron en segmentos arteriales con menores niveles de distensibilidad comparado con las arterias sanas. Las PAC FC mostraron mayor rigidez a nivel del hombro proximal en comparación con las L y FL que se comportan de manera más homogénea en todos sus sectores. Conclusión: las PAC L y FL (consideradas de mayor riesgo) no presentaron el cambio significativo de rigidez parietal observado en las PAC FC, consideradas de menor riesgo de complicación. Estas diferencias biomecánicas relacionadas con la composición global de la PAC podrían tener una implicancia en la patogenia de la complicación de placa.
Introduction: the aterosclerotic disease and its complications are the most frequent cause of death in the world. An analysis of the relationship between structural and mechanic parameters of the carotid aterome plaque (CAP) is mandatory in the need of improving our knowledge concerning the mechanisms that would favor the mechanic fatigue of the plaque material and its complication. Objectives: analize the carotid distensibility in healthy persons and with patients with CAP according to their structural composition. Methods: 100 asymptomatic individuals were studied, with CAP (n=36) and without CAP (n=64). CAP persons were classified according to the standard levels of greys and color mapping in lipidic (L), fibrolipidic (FL) and fibrous/calcified (FC). B-mode Ultrasound with applanation tonometry were combined and the distensibility was quantified along the longitudinal axis in five sectors to the level of the CAP and in the normal carotid artery. Results: 71 CAP (35 L, 16 FL y 20 FC) were classified all in low-level distensibility arterial segments compared to healthy arteries. The FC CAP showed more rigidity in the proximal shoulder compared to the L and FL that behave more homogeneously in all their sectors. Conclusion: the L and FL CAPs (considered of major risk) did not present the parietal rigidity significant change observed in the FC CAP, considered of low complication risk. These biomechanic differences related to the global composition of the CAP could have an implication in the pathogenesis of the plaque complication.
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Humans , Male , Carotid Arteries , Carotid Arteries/physiopathology , Plaque, Atherosclerotic , Plaque, Atherosclerotic/diagnosis , Plaque, Atherosclerotic/ultrastructure , Biomechanical Phenomena , Arterial PressureABSTRACT
OBJECTIVE: To compare the diagnostic performance of high-resolution ultrasound (HRUS) with contrast-enhanced CT and contrast-enhanced magnetic resonance imaging (MRI) with MR cholangiopancreatography (MRCP) to differentiate between adenomyomatosis (ADM) and gallbladder cancer (GBCA). MATERIALS AND METHODS: Forty patients with surgically proven ADM (n = 13) or GBCA at stage T2 or lower (n = 27) who previously underwent preoperative HRUS, contrast-enhanced CT, and contrast-enhanced MRI with MRCP were retrospectively included in this study. According to the well-known diagnostic criteria, two reviewers independently analyzed the images from each modality separately with a five-point confidence scale. The interobserver agreement was calculated using weighted kappa statistics. A receiver operating characteristic curve analysis was performed and the sensitivity, specificity, and accuracy were calculated for each modality when scores of 1 or 2 indicated ADM. RESULTS: The interobserver agreement between the two reviewers was good to excellent. The mean Az values for HRUS, multidetector CT (MDCT), and MRI were 0.959, 0.898, and 0.935, respectively, without any statistically significant differences between any of the modalities (p > 0.05). The mean sensitivity of MRI with MRCP (80.8%) was significantly higher than that of MDCT (50.0%) (p = 0.0215). However, the mean sensitivity of MRI with MRCP (80.8%) was not significantly different from that of HRUS (73.1%) (p > 0.05). The mean specificities and accuracies among the three modalities were not significantly different (p > 0.05). CONCLUSION: High-resolution ultrasound and MRI with MRCP have comparable sensitivity and accuracy and MDCT has the lowest sensitivity and accuracy for the differentiation of ADM and GBCA.
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Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Adenomyoma/diagnosis , Cholangiopancreatography, Magnetic Resonance/methods , Contrast Media , Diagnosis, Differential , Diagnostic Imaging/methods , Gallbladder Neoplasms/diagnosis , Magnetic Resonance Imaging/methods , Observer Variation , ROC Curve , Retrospective Studies , Sensitivity and Specificity , Tomography, X-Ray Computed/methods , Ultrasonography/methodsABSTRACT
Cornual or interstitial pregnancy is a rare form of ectopic pregnancy. In previous reports it accounted for 2~6% of all ectopic pregnancies. Because this unique anatomic location of the implantation site is a highly vascular area, potentially catastrophic hemorrhage from uterine rupture may occur in 15~20% of the cases, and early diagnosis is very important. As sensitive serum beta-hCGmeasurement and imaging techniques have evolved, it is possible to diagnose cornual pregnancies earlier than in the past. Traditional management is cornual wedge resection or hysterectomy by laparotomy. But this invasive treatment method may increase the morbidity and the risk of uterine rupture in subsequent pregnancies, medical treatment with methotrexate has been applied to treat cornual pregnancies, offering an alternative to surgery. Also there have been case reports of laparoscopic treatment of cornual pregnancy. We report a case of viable cornual pregnancy, which was treated successfully by curettage of the uterine cornus under the guidance of high-resolution ultrasound.
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Female , Pregnancy , Cornus , Curettage , Early Diagnosis , Hemorrhage , Hysterectomy , Laparotomy , Methotrexate , Pregnancy, Ectopic , Ultrasonography , Uterine RuptureABSTRACT
Objective To evaluate the application and the good qualities of high-resolution ultrasound and CDFI-guided mammotome minimally invasive biopsy device in the diagnosis and treatment of breast lesions.Methods The common clinical operations and the lesions which were guided mammotome minimally invasive biopsy device by high-resolution ultrasound and CDFI were contrasted.The effects of treatment were evaluated.Results 307 le- sions of 102 patients were removed by this method,and the operational process was successful.Patients' skin lacera- tions were tiny.Only one lesion was clinically diagnosed as mild blood clot under skin,but without other complica- tions.Conclusion Contrasted with the common clinily operations.the high-resolution ultrasound and CDFI-guided mammotome minimally invasive biopsy device in the diagnosis and treatment of breast lesion is effective,and the scar is tiny.It releases patients' pain.
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Objective:To investigate the intervention effect of the compound polygonum cuspidatum sieb.et Zucc.grain on endothelium dependent dysfunction in patients with coronary artery disease.Methods:Twenty-four patients with both confirmed diagnosis of coronary artery disease(diagnosed by coronary arteriography) and endothelium dependent dilation(EDD) [expressed by flow mediated dilation(FMD) examined through high-resolution ultrasound] were enrolled into this investigation.They were divided into Group CAD,and Group HZ at random.Each group consisted of 12 patients.Group HZ,was administered the compound polygonum cuspidatum sieb.et Zucc.grain 10 grams per time,three times a day for 14 consecutive days.EDD0 and EDD14 were examined before and after the administration of the compound polygonum cuspidatum sieb.et Zucc.grain for 14 days.Group of normal control(Group NC) consisted of 12 age-and sex-matched healthy people.Results:EDD0 and EDD14 were(11.76?0.95)% and(11.83?0.70)% in Group NC,(5.37?1.15)% and(5.50?1.01)% in Group CAD which had significant difference compared with Group NC,(5.62?1.22)% and(9.84?1.83)% in Group HZ which were significantly different from those in Group NC.In GroupHZ,EDD14 was higher than EDD0 and had no significant difference compared with Group NC.Conclusion:The compound polygonum cuspidatum sieb.et Zucc.grain can improve endothelium-dependent dysfunction in patients with coronary artery disease.