Glandular Odontogenic Cyst Mimicking Dentigerous Cyst: A Rare Case Report

Background: Glandular odontogenic cyst is an uncommon developmental cyst of odontogenic origin. Till now, around 200 cases have been reported in the English literature, out of which approximately 25 of them are associated with an unerupted tooth. Herein we present a case report of a 7-year-old boy with swelling in the anterior maxillary region which was later diag- nosed as a Glandular odontogenic cyst that mimicked a Dentigerous cyst. Case presentation: A painless swelling was noted in the anterior palatal region. Orthopantamogram was advised which re- vealed a unilocular radiolucency associated with an impacted supernumerary tooth. Provisional diagnosis of Dentigerous cyst was made. The cyst was enucleated in conjunction with peripheral osteotomy. The histopathological examination revealed a cystic capsule with non-keratinized stratified squamous epithelium with 2-4 cell layer thickness, with some areas showing epithelial plaque, microcysts, hobnail cells and few clear cells. Contemplating all the histological features, final diagnosis of Glandular odontogenic cyst was given. Conclusions: The presented case emphasizes the importance of histopathological examination of the unusual and rarely ob- served Glandular odontogenic cyst which can be missed due to similarities with other entities. Recurrence rates being very high, follow up of the cases is imperative.

MRIperformanceofpapillarythyroidcarcinomawithhobnailfeatures / 实用放射学杂志

Objective ToexploretheMRIperformanceofpapillarythyroidcarcinomawithhobnailfeatures(HPTC)andthedifferential diagnosisfromclassicpapillarythyroidcarcinoma(CPTC).Methods Dataof93patientswithconfirmedPTCandMRIexamination oneweekbeforesurgerywereretrospectivelycollected.Thedifferencesoftheage,sex,tumorsize,ADCvaluesand MRIfeaturesof HPTCandCPTCweredetermined.Results 10HPTCand78CPTCwereincludedinthisstudy.ThefrequencyofT2WIsignificantly highsignal,segmentationlinearlowsignal,lacesignandgyrus-likestructureofHPTCwassignificantlyhigherthanthatofCPTC (P=0.000).ComparedtoCPTC,HPTCshowedmoreirregularshape(P=0.005),largervolume(P=0.025),moremixedT2WI andDWIsignals(P=0.002,0.028,respectively),higherADCvalues(P=0.019),anddelayedmass-likeenhancement(P=0.041). Conclusion HPTClesionshavelargervolume,irregularshape,mixedT2WIsignals,mixedDWIsignalsandhigherADCvalues. Significantlyhighsignal,segmentationlinearlowsignal,lacesignandgyrus-likestructurearecommonlyobservedonT2WI.Delayed mass-likeenhancementpatternismorecommon.ThesecharacteristicscouldcontributetothediagnosisofHPTC.

Anastomosing hemangioma with extensive fatty stroma in the retroperitoneum

Anastomosing hemangiomas are a recently recognized benign vascular neoplasm, first described by Montgomery and Epstein in 2009. A few cases have been described in the genitourinary tract, especially in the renal hilum. These are fairly well-demarcated lesions with lobules of sinusoidal-like capillaries lined by hobnail endothelial cells containing eosinophilic hyaline globules in the cytoplasm. Extramedullary hematopoiesis has been described in a few cases, along with large feeding vessels. A predominant adipocytic component has been described in only one case.[9] We describe a case of a retroperitoneal anastomosing hemangioma occurring in an extrarenal site in a 53-year-old female, followed by a review of the current literature.

Hemangioma hemosiderótico-targetoide: Presentación de un caso clínico / Targetoid hemosiderotic hemangioma: A case report

Las anomalías vasculares han sido clasificadas por primera vez en 1982, por Mulliken y Glowacki y recientemente, la Sociedad Internacional para el Estudio de las Anomalías Vasculares (ISSVA) modificó dicha clasificación, por la que hoy es aceptada mundialmente, que divide a las lesiones vasculares en tumorales y malformaciones. Dentro de la misma, encontramos una variedad de tumores, desde los más frecuentes como los hemangiomas infantiles, hasta los de menor frecuencia, integrando los síndromes clínicos y genéticos. El hemangioma hemosiderótico targetoide (HHT), también conocido como hemangioma hobnail, se encuentra dentro de dicha clasificación en el grupo de "otros" tumores vasculares, por su baja frecuencia. Fue descrito por primera vez por Santa Cruz y Aronberg en 1988, como una proliferación vascular benigna localizada con más frecuencia, en el tronco y las extremidades de los adultos jóvenes o de mediana edad. El objetivo es la presentación de un caso de hemangioma hobnail, patología vascular que se encuentra en constante revisión en la actualidad, profundizar en el conocimiento de los tumores vasculares, su clasificación y marcadores inmunohistoquímicos, revisar la bibliografía nacional e internacional y determinar bajo qué clasificación incluiríamos a esta entidad. La finalidad también es realizar un exhaustivo análisis de los diagnósticos diferenciales de esta patología, teniendo en cuenta la práctica clínica y demostrar como las nuevas tecnologías de diagnóstico, nos ayudan a aproximarnos al origen de la misma.

Vascular anomalies have been classified by Mulliken and Glowacki in 1982 and recently modified this classification by the International Society for the Study of Vascular Anomalies (ISSVA) today accepted worldwide, dividing vascular tumors and malformations. Within the same we find a variety of tumors from the more frequent as infantile hemangiomas, to the others with lower frequency, integrating clinical and genetic syndromes. Targetoid haemosiderotic haemangioma (THH), also known as hobnail haemangioma, is within that classification in the group of "other" vascular tumors due to their low frequency. It was described by Santa Cruz and Aronberg in 1988. It`s a benign vascular proliferation that arises most commonly on the trunk and limbs of young or middle-aged adults. The aim is to present a case of hobnail haemangioma, which is constantly being revised now a days, deepen of the knowledge of vascular tumors, their classification and immunohistochemical markers, review national and international literature and determine under what classification we would include this entity. The purpose is also to conduct a thorough analysis of the differential diagnosis of this disease, taking into account the clinical practice and demonstrate how new diagnostic technologies help us to approach it´s origin.

Hemangioma hemosiderótico targetoide: revisión a propósito de cuatro casos / Targetoid Hemosiderotic Hemangioma: Revision based on four cases

El hemangioma hemosiderótico targetoide, conocido también como hobnail hemangioma, es un tumor vascular benigno que se localiza preferentemente en tronco y miembros. La forma clásica (o targetoide) se presenta como una pápula pequeña, solitaria, violácea-amarronada, rodeada por una zona pálida y un anillo equimótico periférico. Existe controversia acerca del origen vascular capilar o linfático de este tumor, aunque estudios inmunohistoquímicos recientes avalan su naturaleza linfática. Presentamos cuatro casos pediátricos de hemangioma hemosiderótico targetoide con manifestaciones clínicas atípicas.

Targetoid hemosiderotic hemangioma, also known as hobnail hemangioma, is a benign vascular tumor that mainly affects the trunk and limbs. Its classical (or targetoid) appearance is that of a small, solitary, violaceus to brown papule surrounded by a pale halo and a peripheral equimotic ring. Controversy exists about the vascular capillary or lymphatic origin of this tumor; however, recent immuhistochemical studies support its lymphatic nature. We discuss four pediatric cases of targetoid hemosiderotic hemangioma with atypical presentation.

A Case of Hobnail Hemangioma That Occurred Together with Angiolipoma / 대한피부과학회지

Hobnail hemangioma is a benign vascular tumor that typically presents as a small, solitary lesion on the trunk or limbs of young or middle-aged persons. Characteristically,the tumor has a targetoid appearance where a violaceous papule is surrounded by an ecchymotic rim. Hobnail hemangioma is characterized by a biphasic growth pattern of the neoplastic vascular structures and prominent matchstick-like endothelial cells. Based on the positivity of the endothelial cells for monoclonal antibody D2-40, it has been proposed that this tumor displays lymphatic differentiation. Angiolipomas are benign subcutaneous tumors that consist of mature adipocytes and blood vessels. They are usually multiple and they typically occur in young adults with an obvious male predilection. We describe here a case of hobnail hemangioma that occurred together with angiolipoma in an 8-year-old girl, who had a violaceous papule encircled by a peripheral ecchymotic halo on the left heel.

A Case of Targetoid Hemosiderotic Hemangioma / 대한피부과학회지

Targetoid hemosiderotic hemangioma (THH) is a solitary vascular tumor typically occurring in young or middle-aged persons, and affecting the limbs or trunk. Characteristically, the lesion has a "targetoid" appearance where a violaceous papule is surrounded by an ecchymotic or brown ring that can expand or subsequently disappear with the persistence of the central papule. THH is characterized histologically by dilated vascular structures in the superficial dermis lined by prominent hobnail endothelial cells and collagen-dissecting, rather narrow neoplastic vessels in the deeper parts of the lesion. We report a 17-year-old girl who presented showing typical clinical and histological features of targetoid hemosiderotic hemangioma.

A Case of Targetoid Hemosiderotic Hemangioma / 대한피부과학회지

Targetoid hemosiderotic hemangioma (THH) is a solitary vascular tumor affecting the limbs or trunk, typically occurring in young or middle-aged persons. The lesion has a "targetoid" appearance, where a violaceous papule is surrounded by an ecchymotic or brown ring. THH is characterized histologically by dilated vascular structures in the superficial dermis lined by prominent hobnail endothelial cells and collagen-dissecting, rather narrow neoplastic vessels in the deeper parts of the lesion. It is important to distinguish this tumor from patch stage of Kaposi's sarcoma, solitary angiokeratoma, and retiform hemangioendothelioma. We report a 12-year-old girl showing typical clinical and histological features of targetoid hemosiderotic hemangioma.

A Case of Childhood Hobnail Hemangioma / 대한피부과학회지

Hobnail hemangioma is a benign vascular tumor that typically presents as a small, single lesion on the skin of the trunk or limb. It occurs mainly in young or middle-aged adults (mean age: 30 years) but rarely in childhood. Histologically, hobnail hemangioma is characterized by a biphasic growth pattern, with dilated vascular spaces lined by hobnail endothelial cells in the superficial dermis, and collagen dissection narrow vascular channels in the deeper dermal parts, as well as inflammatory aggregates, fibrosis, and hemosiderin deposits. We report a case of hobnail hemangioma in a 10-year-old girl who had a violaceous papule surrounded by an ecchymotic halo on the left thigh. She underwent treatment with surgical excision with primary closure. To the best of our knowledge, our case is the first reported case of childhood hobnail hemangioma in Korean dermatological literatures.

A Case of Hobnail Hemangioma / 대한피부과학회지

Hobnail hemangioma is a benign vascular tumor characterized by a violaceous or brown papule that is surrounded by a thin pale area and a peripheral ecchymotic ring. Histologically the lesion consists of a superficial dermal vascular proliferation. In the upper dermis, dilated vascular spaces often lined by endothelial cells that protrude in to the lumina and closely resemble hobnail. In the deeper dermis, slit-like vascular structures appeared to dissect between collagen bundles. It is important to distinguish these tumors from patch stage of Kaposi's sarcoma, solitary angiokeratomas, retiform hemangioma and progressive lymphangioma. We report a 29-year-old woman showing typical clinical and histological features of hobnail hemangioma.

A Case of Hobnail Hemangioma

Hobnail hemangioma(HH) is a benign acquired vascular tumor of endothelial origin which should be differentiated from other malignant vascular neoplasm such as Kaposi's sarcoma or angiosarcoma. We report a case of hobnail hemangioma in a 21-year-old woman who had a dusky-red patch on her left shin. Histologically, ectatic vascular channels with a single layer of plumped endothelial cells were seen and the vascular channels seemed to dissect the collagen bundles. She underwent treatment with surgical excision with primary closure.

A Case of Hobnail Hemangioma / 대한피부과학회지

Hobnail hemangioma, also known as "targetoid hemosiderotic hemangioma", represents a distinctive benign vascular tumor, characterized histologically by a biphasic growth pattern of dilated vascular structures lined by prominent hobnail endothelial cells in the superficial dermis, and collagen dissection by angulated vessels in deeper parts of the lesion. It is important to distinguish this tumor from patch stage Kaposi's sarcoma, retiform hemangioendothelioma and progressive lymphangioma. We report a 26-year-old man showing typical clinical and histological features of hobnail hemangioma.