1.
Chinese Pharmacological Bulletin
;
(12)1987.
Article
in Chinese
| WPRIM
| ID: wpr-561164
ABSTRACT
To date, pancreatitis lacks of specific pharmacological therapy. Recently, it has been found that cytosolic Ca2+ overload causes pancreatitis. This article summarized the earliest events of Ca2+ transport in pancreatic acinar cell during pancreatitis and the influence of bile, alcohol, and hyperlipidaemia.Abnormal Ca2+ signal can be inhibited by caffeine. Based on these results, potential therapeutic targets are suggested.