1.
Chinese Pharmaceutical Journal
;
(24): 116-1999.
Article
in Chinese
| WPRIM
| ID: wpr-598313
ABSTRACT
OBJECTIVE:To determine whether bacterial endotoxins test(BET) can replace the pyrogen test for the sodium bicarbonate injection.METHODS:The comparative experiment of tachypleus amebocyte lysate(TAL) and rabbits were studied to determine the sensitivity.RESULTS:The sensitivity of TAL test was 0.125 EU.ml-1, 12 times higher than that of using rabbits.CONCLUSIONS:BET may replace pyrogen test.