ABSTRACT
@#AIM: To investigate interocular differences in macular ganglion cell complex(mGCC)thickness in normal healthy subjects, and to determine cutoffs for interocular differences in mGCC thickness in normal healthy subjects.<p>METHODS: This was a cross-sectional study. mGCC thickness were measured in 236 healthy volunteers(472 eyes)using optical coherence tomography(OCT). The differences and the relationships of mGCC thickness between right and left eyes were analyzed. <p>RESULTS: For the right eyes, the mean average mGCC thickness was 91.99±6.61μm, and for the left, 91.75±9.93μm, with no significant difference. The mean mGCC thickness among superior and inferior in the right eye were 92.32±6.66μm and 91.27±8.87μm, respectively. The mean mGCC thickness among superior and inferior in the left eye were 92.05±6.55 and 91.51±6.76μm, respectively. It is comparable between the two eyes at different area. The P2.5 and P97.5 percentiles of interocular difference for mean average mGCC thickness were -4.82μm and 4.36μm, for superior mGCC thickness, -5.79μm and 6.42μm, and for inferior mGCC thickness, -7.21μm and 6.28μm. There was a strong correlation in the corresponding area between the right and left eyes for the mGCC thickness.<p>CONCLUSION: mGCC thickness shows significant interocular symmetry in normal subjects. Interocular difference exceeding the normal limits should be considered significantly asymmetrical, and may be indicative of glaucoma.
ABSTRACT
PURPOSE: To evaluate the interocular symmetry of microvascular parameters measured by optical coherence tomography angiography (OCTA) in normal eyes of Korean adults. METHODS: We retrospectively reviewed the retinal microvascular structure of 91 healthy Korean subjects (182 eyes). We used OCTA to measure the area of the foveal avascular zone (FAZ), vessel density (VD), and perfusion density (PD) in both eyes. Intraclass correlation coefficients (ICCs), coefficients of variation (CVs), and Pearson correlation coefficients were calculated to evaluate the extent of agreement and correlations between binocular OCTA measurements. RESULTS: Both eyes had similar microvascular characteristics: FAZ area (right eye: 0.31 ± 0.11 mm², left eye: 0.30 ± 0.10 mm², p = 0.98), FAZ perimeter (right eye: 2.35 ± 0.45 mm, left eye: 2.36 ± 0.39 mm, p = 0.86). VD 1-mm center (right eye: 9.42 ± 2.75, left eye: 9.14 ± 2.96, p = 0.163), full area (right eye: 19.94 ± 1.65, left eye: 19.72 ± 1.76, p = 0.285), and PD 1-mm center (right eye: 0.16 ± 0.05, left eye: 0.16 ± 0.05, p = 0.151), full area (right eye: 0.36 ± 0.03, left eye: 0.36 ± 0.04, p = 0.716). All ICC values were above 0.8 and all CVs below 10%. CONCLUSIONS: The microvascular structure, as represented by the VD, PD, and FAZ area measured via OCTA, was bilaterally symmetric in normal eyes of Korean adults.
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Adult , Humans , Angiography , Perfusion , Retinaldehyde , Retrospective Studies , Telescopes , Tomography, Optical CoherenceABSTRACT
AIM: To observe the interocular symmetry of primary angle-closure suspects` (PACS) parameters using IOL Master.METHODS: A cross-sectional observational study.Totally 112 eyes from 56 subjects were enrolled to detect the difference of the bilateral axial length (AL), anterior chamber depth (ACD) and white to white distance(WTW), and to evaluate the correlation between the interocular differences of △AL, △ACD and △WTW and age, gender.RESULTS: All the parameters were analyzed by paired-samples t test and there were no significant interocular difference (P>0.05).There was no relation of ΔAL,ΔACD and ΔWTW with age and gender.CONCLUSION: Interocular symmetry of parameters by IOL Master was observed in PACS, and we found that the symmetry would not be altered when the age and gender had changed.