ABSTRACT
Objective: The aim was to govern the intradialytic hypotension frequency among patients on maintenance dialysis and its relationship with various risk factors. Study design: A Cross-Sectional analytical study. Place and duration: In the Nephrology department of Services Hospital Lahore for Six months duration from January 2019 to June 2019. Methods: The intradialytic hypotension frequency was determined and specified as a percentage. All statistical variables such as weight, age, blood flow, dialysate temperature, standard deviation and mean were recorded. The relationship between qualitative risk factors and intradialytic hypotension was paralleled using the Student’s t-test with a z-test for proportional and quantitative risk factors. Results: In total sessions; Symptomatic intradialytic hypotension was recorded in 5.4%. In the hypotensive group the pre-dialysis diastolic, systolic, pulse, blood pressure was higher than the other groups with substantial p-values. In the hypotensive group, diastolic, systolic and low mean blood pressure was lesser than the other groups. However, in pulse rate the mean change between the 2 groups (normotensive group, p=0.8 to -2.4 ± 11.1 and hypotensive group -2.1 ± 14.1) did not significantly change with the drop in B.P. Cardiac events were also higher significantly in the hypotensive group.
ABSTRACT
0bjective To investigate the occurrence of frequent intradialytic hypotension in hemodialysis patients and Analyzed influencing factors. Methods The 1 933 hemodialysis sections of 156 maintenance hemodialysis patients in the Huashan hospital affiliated to Fudan University in Shanghai were selected, and divided into frequent intradialytic hypotension and non- frequent intradialytic hypotension depending on whether the incidence of intradialytic hypotension is greater than 20%, and the patients' dialysis data and biochemical examination data are collected for the analysis of influencing factors. Results The incidence of frequent IDH in maintenance hemodialysis patients was 62.18%(97/156), and the pre-dialysis blood pressure of frequent IDH patients were higher than non-frequent IDH patients, frequent IDH patients: (134.02±21.01)/(73.85±10.73) mmHg(1 mmHg=0.133 kPa), non-frequent IDH patients: (124.66 ± 17.89)/(69.32 ± 10.65) mmHg, (t=-2.851,-2.558, P＜0.05), but lower in post-dialysis, frequent IDH patients:(114.91±19.21)/(68.38±11.41) mmHg, non-frequent IDH patients: (127.90± 20.58)/(74.46±11.79) mmHg, (t=3.989, 3.189, P＜0.01). Binary Logistic regression analysis showed that hemoglobin ( OR=0.354, P=0.015) and high-density lipoprotein ( OR=0.155, P=0.003) were protective factors for the occurrence of frequent IDH, and ultrafiltration volume/weight ( OR=6.021, P=0.002) and N-terminal pro-brain natriuretic peptide ( OR=2.687, P=0.020) were risk factors. Conclusions The incidence of frequent IDH in hemodialysis patients is high, and patients with high filtration rate, high N-terminal pro-brain natriuretic peptide, low hemoglobin and high density lipoprotein should be paid close attention to. It is recommended to regularly monitor patients' biochemical indicators, strengthen blood pressure monitoring for high-risk groups, and timely deal with the symptoms of low blood pressure.
ABSTRACT
Objective To explore the effects of resistance exercise on intradialytic blood pressure variability and the lowest blood pres-sure. Methods From September, 2015 to March, 2016, 80 patients with intradialytic hypotension frequently during maintenance hemodialy-sis were included, and divided into control group (n=40) and intervention group (n=40) by drawing lots. Both groups accepted routine nurs-ing, while the intervention group accepted resistance exercise during hemodialysis. The coefficient of variation (CV) of blood pressure and the lowest blood pressure were compared twelve weeks later. Results The CV of systolic blood pressure was less in the intervention group than in the control group (t=-4.356, P4.122, P<0.001). Conclusion Resistance exercise may reduce the intradialytic systolic blood pressure variability and increase the lowest blood pressure in pa-tients with frequent intradialytic hypotension.