ABSTRACT
OBJECTIVE:To evaluated the utilization of antineoplastics for intravenous use in our hospital and to provide references for clinical medication and pharmacoeconomic research. METHODS:The utilization of antineoplastics in our hospital from 2007 to 2009 was statistically analyzed in respect of consumption sum and DDDs. RESULTS:Amount and consumption sum of antineoplastics in our hospital increased rapidly in recent 3 years. The DDDs of drug were markedly different from their consumption sum rank,for example Docetaxel injection. Antineoplastics for intravenous use sourcing from plants took up big proportion of antineoplastics and they accounted for 50% of the top 10 antineoplastics in the list of consumption sum. CONCLUSION:The antineoplastics for intravenous use in our hospital basically remain stable in category and develop rapidly in recent years,which focus on reasonable price,exact therapeutic effect and less adverse reaction.
ABSTRACT
Methamphetamine is one of the most popular abuse drug in the South Korea. Intracranial hemorrhage or ischemic stroke have been well known as one of the complications with methamphetamine abuse. We experienced two cases with cerebral vasculopathy which had developed after intravenous use of methamphetamine. The first patient was a previously healthy 20-year-old woman, who was admitted because of drowsy mentality with left hemiparesis and dysarthria. The second patient was a 24-year-old man who was admitted because of seizure and left extremity weakness. They reported several intravenous administration of methamphetamine during previous months. In both case, brain CT showed cerebral infarction compatible with vascular territories. And also, carotid angiographys demonstrated that multiple intracranial vessels were involved with narrowing and stenotic nature, consisting with vasculitis in the both cases.