Por uma pesquisa e escrita parafusos: pulos, rodopios e invenções de si / For research and writing screws: jumps, twirls and inventions of self / Para tornillos de investigación y escritura: saltos, giros e autoinvenciones

O artigo parte da aposta na pesquisa como uma prática em movimento, na composição de territórios do ato de pesquisar como uma experiência. Inspiradas(os) na força disruptiva do torcer-retorcer dos Parafusos (folguedo sergipano, derivado de práticas de resistência à escravidão dos povos pretos), propomos um método-pensamento de inventar modos de ver, dizer e narrar a partir daquilo que está ao nosso redor, uma posição em relação ao mundo e a si mesmo, engendrando a ideia de que este mundo não é um dado, mas um efeito de nossas práticas. A partir dessa perspectiva, intentamos interpelar as próprias práticas discursivas e não discursivas da Psicologia, em favor de abrir trilhas nas quais esse saber possa refundar sua própria história, acentuando suas descontinuidades e heterogeneidades e, com isso, uma atitude de fazer frente às tendências colonialistas, agora em suas versões neoliberais. Esse modo de pesquisar se faz por: operar uma ideia-método genealógico-cartográfica e uma escrita polifônica; produzir máquinas de guerras nômades, minoritárias, pós-identitárias, decoloniais; e inventar com aquilo que está ao nosso redor em favor de saberes e fazeres das redes locais, que, tais como a planta mangabeira, não se deixam domesticar.(AU)

The article starts from the research as a moving practice; in the composition of territories of the act of researching as an experience. Inspired by the disruptive force of the twisting-twining of the Screws (revelry from Sergipe, derived from practices of resistance to the slavery of black people), we propose a thought-method of inventing ways of seeing, saying, and narrating from what is around us, a position in relation to the world and itself, engendering the idea that this world is not a given, but an effect of our practices. From this perspective, we try to question the very discursive and non-discursive practices of Psychology, in favor of opening trails, in which this knowledge can refund its own history, accentuating its discontinuities and heterogeneities and, thus, an attitude of facing the colonialist tendencies, now in their neoliberal versions. This way of searching is done by: operating a genealogical-cartographic idea-method and polyphonic writing; producing nomadic, minority, post-identity, decolonial war machines; and inventing with what is around us, in favor of knowledge and practices of local networks, which, like the mangabeira plant, do not allow domestication.(AU)

Este artículo parte de la investigación como práctica en movimiento, en la composición de territorios del acto de investigar como experiencia. Inspirándonos en la fuerza disruptiva de torsión-retorsión de los Tornillos (juerga de Sergipe, derivada de prácticas de resistencia a la esclavitud de los negros), proponemos un método de pensamiento para inventar formas de ver, decir y narrar a partir de lo que nos rodea, una posición en relación con el mundo y con él mismo, el cual constituye la idea de que este mundo no es un hecho, sino un efecto de nuestras prácticas. Desde esta perspectiva, pretendemos cuestionar las prácticas discursivas y no discursivas de la Psicología en favor de abrir caminos, en las cuales este conocimiento pueda refundar su propia historia, acentuando sus discontinuidades y heterogeneidades y, así, una actitud de hacer ante las prácticas colonialistas, ahora desde una perspectiva neoliberal. Este modo de investigación se realiza mediante: el funcionamiento de un método-idea de escritura genealógica, cartográfica y polifónica; la producción de máquinas de guerra nómadas, minoritarias y posidentitarias; y la composición con el tema que nos rodea a favor del conocimiento y las redes locales que no puede ser domesticada, como el árbol mangabeira.(AU)

(Re)apresentando o território escolar: uma possibilidade inventiva / (Re)presenting the school territory: an inventive possibility / (Re)presentar el territorio escolar: una posibilidad inventiva

Resumo Este artigo propõe-se a conhecer e problematizar um território escolar, do interior do RS, em busca da construção de um mapa. Nesta construção percorre-se o campo entre as relações e as práticas com/na escola, cartografando seus trajetos já estabelecidos e seus desvios, entre visibilidades e invisibilidades. Tem-se como objetivos cartografar as possibilidades de invenção na escola e explorar as relações dos sujeitos com/no espaço escolar. Os passos desta pesquisa foram construídos por meio da cartografia, método da pesquisa-intervenção, problematizando implicações, observações e intervenções da cartógrafa com as paisagens vistas e construídas. Com isto encontrou-se analisadores - o portão, o círculo e o circo - que possibilitaram experenciar e construir estas paisagens que, recheadas de sentimentos, forças e formas, (re)criaram um mapa do território, (re)apresentado na escrita deste artigo. Por fim, compreende-se que é preciso sair dos extremos e vivenciar os "entres" que configuram e compõem o território. A pesquisadora-cartógrafa que habita o campo da psicologia buscou, a partir desta produção, um movimento de inquietações, deixando aqui a sugestão de seguir-se fora de tais extremos, escutar-se os modos instituídos, dar voz aos desejos instituintes e poder criar entre os dois, permitindo-se ser artista ao inventar diferentes modos de rel(ação) no território escolar.

Abstract This article proposes to meet and to discuss a school territory, in the interior of the RS, in search of building a map. This construction runs through the field between the relationships and practices with/in school charting their routes already established and its deviations, between visibilities and invisibilities. It has as objectives to chart the possibilities of invention at school and how to explore the relationship of subjects with/in the school space. For it, is through cartography, research-intervention method, that the steps of this research are built, questioning implications, observations and interventions of the cartographer with the views and landscapes built. With this, it was possible to find analyzers - the gate, the circle and the circus - which enabled experience and to build these landscapes, filled with feelings, strengths and shapes, (re) created a map of the territory, (re) presented in the writing of this article. Finally, it is understood that it is necessary to leave the extremes and experience the "in-betweens" that configure and compose the territory. The researcher-cartographer who inhabits the field of psychology sought, from this production, a movement of concerns, leaving here the suggestion of moving away from such extremes. Listening to instituted modes, giving voice to instituting desires and being able to create between the two, allowing oneself to be an artist by inventing different modes of relationship(action) in the school territory

Resumen Este artículo se propone conocer y problematizar un territorio escolar, en el interior de RS, en busca de la construcción de un mapa. En esta construcción se recorre el campo entre las relaciones y prácticas con/en la escuela, mapeando sus caminos ya establecidos y sus desvíos, entre visibilidades e invisibilidades. Los objetivos son mapear las posibilidades de invención en la escuela y explorar las relaciones de los sujetos con/en el espacio escolar. Los pasos de esta investigación fueron construidos a través de la cartografía, un método de investigación-intervención, problematizando implicaciones, observaciones e intervenciones del cartógrafo con los paisajes vistos y construidos. Con ello, se encontraron analizadores -la puerta, el círculo y el circo- que permitieron experimentar y construir estos paisajes que, llenos de sentimientos, fuerzas y formas, (re)crearon un mapa del territorio, (re)presentaron en la redacción de este artículo. Finalmente, se entiende que es necesario salir de los extremos y experimentar los "entremedios" que configuran y componen el territorio. El investigador-cartógrafo que habita el campo de la psicología buscó, a partir de esta producción, un movimiento de inquietudes, dejando aquí la sugerencia de alejarse de tales extremos. Escuchar los modos instituidos, dar voz a los deseos instituyentes y poder crear entre los dos, permitiéndose ser artista inventando diferentes modos de relación (acción) en el territorio escolar.

Protótipo de colchão pneumático ergonômico para o manejo de paciente com mobilidade física prejudicada / Ergonomic pneumatic mattress prototype for the management of patients with impaired physical mobility

Resumo: Trata-se do desenvolvimento de tecnologia para assistência na saúde, com depósito de Patente ­ Modelo de Utilidade, denominado de Colchão Pneumático Ergonômico com Bolsões Insufláveis Individualmente. A finalidade dessa inovação tecnológica é auxiliar na mobilização e reposicionamento de pacientes com mobilidade física prejudicada, restritos ao leito, com alto risco de lesões cutâneas, complicações pulmonares e outros agravos à saúde. A mudança de decúbito, um dos principais cuidado de enfermagem, exige técnica adequada, disponibilidade de mais de um profissional qualificado e uso de dispositivos, como coxins de posicionamento convencionais ou improvisados. Tem como objetivo reduzir riscos de agravos à saúde do paciente e doenças ocupacionais, como lombalgia e doenças osteoarticulares nos profissionais de saúde ou cuidadores em domicílio. A tecnologia foi projetada com bolsões de diferentes dimensões, de acordo com cada região corporal, os quais possuem válvulas pneumáticas internas, que permitem insuflar individualmente as câmaras de ar presentes na estrutura. Um teclado matricial recebe comandos para insuflar e desinflar os bolsões de ar pela mangueira pneumática, de modo a permitir o reposicionamento do paciente sem necessidade de força própria. Baseado em conhecimento inédito, introduziu novidade, resultando em nova tecnologia para o ambiente social e produtivo. É uma inovação radical, disrruptiva com impacto significativo no ambiente de cuidado, a qual apresenta blocos em diferentes dimensões, insufláveis individualmente, com uma camada de espuma entre a câmara de ar e a cobertura externa, cintas de fixação para estabilidade do colchão, confeccionado com tecido macio, impermeável e de boa elasticidade. Caracteriza-se como tecnologia de alta complexidade, pois associa diferentes tipos de conhecimento e interage com múltiplos saberes, na solução do problema identificado na prática clínica. O impacto social e econômico ocorre pela melhoria da qualidade da assistência, redução de agravos e, consequentemente, redução de custos ao sistema de saúde. Aplicável em diversos cenários de cuidado, como hospitais, casas de longa permanência e domicílio, tem potencial para abrangência nacional e internacional. Atende uma demanda profissional, pois oferece condição ergonômica adequada para o manejo de pacientes restritos ao leito. Com depósito de Patente no Instituto de Propriedade Industrial (INPI), sob o Protocolo de Número BR202022008156-0, está disponível para transferência da tecnologia entre a organização pública (Universidade ­ Pós-Graduação) e a Indústria, resultando em inovação que necessariamente aperfeiçoa o processo de cuidar e o serviço de saúde.

Abstract: This is the development of technology for health care, with the filing of a Patent ­ Utility Model, called Ergonomic Pneumatic Mattress with Individually Inflatable Pockets. The purpose of this technological innovation is to assist in the movement and repositioning of patients with impaired physical mobility, restricted to bed, with a high risk of skin lesions, pulmonary complications and other health problems. Changing positions, one of the main nursing care procedures, requires adequate technique, the availability of more than one qualified professional and the use of devices, such as theoretical or improvised positioning pads. It aims to reduce risks of harm to the patient's health and occupational diseases, such as low back pain and osteoarticular diseases in health professionals or caregivers at home. The technology was designed with pockets of different dimensions, according to each body region, which have internal pneumatic valves, which allow individually inflating the air chambers present in the structure. A matrix keyboard receives commands to inflate and deflate the air pockets through the pneumatic hose, in order to allow the patient to be repositioned without the need for its own strength. Based on innovative knowledge, innovation, generated in new technology for the social and productive environment. It is a radical, disruptive innovation with a significant impact on the care environment, which features blocks in different dimensions, individually inflatable, with a layer of foam between the air chamber and the outer cover, fastening straps for the mattress pad, made with soft fabric, waterproof and good elasticity. It is characterized as a highly complex technology, as it associates different types of knowledge and interacts with multiple types of knowledge in order to solve the problem identified in clinical practice. The social and economic impact occurs by improving the quality of care, reducing injuries and, consequently, reducing costs to the health system. Applicable in different care settings, such as hospitals, long-term care facilities and at home, it has the potential for national and international coverage. It meets a professional demand, as it offers adequate ergonomic conditions for the management of bedridden patients. With a patent filed at the Industrial Property Institute (INPI), under Protocol Number BR202022008156-0, the technology is available for download between the public organization (University - Graduate) and the Industry, generated in innovation that necessarily improved the care process and the health service.

Practice and analysis of empowerment reform of service invention in medical institutions / 中华医学科研管理杂志

Objective:To stimulate innovation vitality, the government promulgated the Pilot Implementation Plan for Granting Scientific and Technological Achievements Ownership or Long- term Use Right to Scientific Research Investigators. As one of the 40 pilot institutions, Beijing JiShuiTan Hospital attached great attention to it and, through the exploration and practice of pilot work, combined with the transformation of medical institutions' achievements Status quo, summarized the experiences of job scientific and technological achievements empowerment. Methods:Explored the mechanism and mode to empower researchers with the ownership or long-term right of service invention according to the policy review and case studies.Results:Developed hospital-level empowerment reform program and related supporting documents, Beijing JiShuiTan Hospital has completed the first empowerment work in Beijing.Conclusions:The reform of empowering scientific and technological achievements gives a new pathway to transform scientific and technological achievements in medical institutions, which will promote the transformation process of service invention-creation.

Research on the development of bio-pharmaceutical industry integration and collaborative innovation in the Yangtze River Delta under the mode of Industry-University-Research cooperation / 中国药科大学学报

@#After the integration of Yangtze River Delta was elevated and developed into a national strategy, few domestic studies have been conducted to explore the integrated and collaborative development of biopharmaceutical industry in the Yangtze River Delta region, which, as an important region of biopharmaceutical industry in China, has initially formed the development mode of industrial clusters. In this study, based on the industry-university-research model of patent and fund project cooperation, the social network analysis (SNA) method is used to analyze and study the cooperation of patent and Major Projects of National Natural Science Foundation of China in the biopharmaceutical industry in the Yangtze River Delta region. The study shows that the industry-university-research cooperation in the biomedical field in the Yangtze River Delta region is still in the development stage and the degree of integration needs to be improved. Universities and research institutes are more inclined to cooperate with enterprises for invention patents and with other universities for fund project research.It is suggested that the Yangtze River Delta region should adopt the deep integration mode of industry-university-research, relevant leading scientific research institutions should establish open innovation platforms, and pharmaceutical universities should cultivate innovative talents with the advantages of their disciplines, and adopt "Revealing the List and Taking Command" or other ways to tackle key core technologies.

Clinical analysis of 10 cases of refractory tracheoesophageal fistula treated with novel double disc-shaped gastrointestinal occluder / 中华消化杂志

Objective:To evaluate the safety and clinical efficacy of the novel double disc-shaped gastrointestinal occluder (hereinafter referred to as occluder) in treatment of refractory tracheoesophageal fistula (TEF).Methods:From July 1, 2020 to January 31, 2021, 10 patients with refractory TEF treated with occluder at Department of Gastroenterology, the First Affiliated Hospital with Nanjing Medical University were collected. The patients′ clinical data such as gender, age, body mass index and fistula diameter were recorded. The success rate of operation, intraoperative and postoperative complications, operation time, postoperative hospital stay, efficacy of fistula closure and postoperative recovery were analyzed. The Karnofsky score and body mass index of patients 1 month and 3 months after operation were compared with those before operation for curative effect evaluation. Paired t test was used for statistical analysis. Results:Among the 10 TEF patients, there were 7 males and 3 females, the median age was 64.5 years old (ranged from 49.0 to 78.0 years old), the body mass index was (18.0±2.5) kg/m 2 and the diameter of the fistula was (1.2±0.6) cm. Occluder placement was successful in all patients. The operation time was (17.6±7.8) min (ranged from 7.0 to 30.0 min). Two cases had little bleeding during the operation, and there was no bleeding after the operation. The postoperative hospital stay was (5.9±4.0) d (ranged from 1.0 to 12.0 d). Among the 10 TEF patients, fistula of 5 patients were completely blocked, 4 cases were partially blocked and 1 case was ineffectively blocked, the effective rate of blocking was 9/10. One month follow-up after operation showed that the symptoms of choking and coughing during eating were significantly improved in 9 patients, and the symptoms of choking and coughing during eating were significantly improved in 1 patient after waist diameter of 12 mm occluder was replaced with the occluder of 15 mm. The 3-month follow-up after operation showed that the occluders were in the right place in 8 patients, the occluder was displaced in 1 patient and the occluder was removed and treated with enteral nutrition. One patient died due to the recurrence of esophageal cancer. The Karnofsky score of TEF patients 3 months after operation and the body mass index of TEF patients 1 month and 3 months after operation were higher than those before operation (70.0±34.0 vs. 46.0±10.7, (19.32±2.59) and (19.73±2.92) kg/m 2 vs. (18.03±2.50) kg/m 2), and the differences were statistically significant ( t=-3.09, -2.37 and -2.82, all P<0.05). Conclusions:Gastrointestinal occluder is safe and effective in the treatment of refractory TEF.

Le savoir y faire de la gambiarra / O saber saber fazer da gambiarra / The applied know-how of the workaround

Pour discuter le thème plus général de l'invention qui se présente dans la clinique psychanalytique, cet article propose de penser la question des solutions de contournement comme des cas particuliers d'invention marqués par la dimension de la précarité. Cette précarité nous intéresse dans la mesure où elle nous permet d'accéder à une lecture non idéalisée de ce que Lacan formule comme invention sur le destin donné au symptôme dans le terme d'une psychanalyse, qui serait une manière de faire avec quelque chose pour laquelle il n'y a pas de programmation symbolique définie. Dans cette perspective, nous pensons que la pratique du psychanalyste actualise le bricolage de la solution de contournement comme une fuite vers la singularité inventive.

Visando discutir o tema mais geral da invenção que se apresenta no âmbito da clínica psicanalítica, este trabalho propõe pensar a questão da gambiarra como um caso particular de invenção marcada pela dimensão da precariedade. Essa precariedade interessa na medida em que nos permite alcançar uma leitura não idealizada do que Lacan formula como invenção acerca do destino dado ao sintoma no termo de uma psicanálise, que seria um modo de se haver com algo para o qual não se dispõe de uma programação simbólica definida. Nessa perspectiva, acreditamos que a prática do psicanalista atualiza a bricolagem da gambiarra como um escape para a singularidade inventiva.

In order to discuss the more general theme of the invention that presents itself in the scope of psychoanalytic clinic, this work propose to think about the issue of the workaround as a particular case of invention marked by the dimension of precariousness. This precariousness is of interest hereto the extent that it allows us to achieve a non-idealized reading of what Lacan formulates as an invention to describe the destiny given to the symptom at the end of a psychoanalysis, which would be a way of dealing with something for which there is no predefined symbolic setting. From this perspective, we believe that the psychoanalyst's practice updates the DIY aspect of the workaround as an escape towards the inventive singularity.

Formação inventiva em psicologia: problematizações à luz dos novos paradigmas da ciência contemporânea / Inventive Formation in psychology: problematizations in the light of the new paradigms of contemporary Science / Formación inventiva en psicología: problematizaciones a la luz de los nuevos paradigmas de la ciencia contemporánea

Este artigo discute a formação acadêmica em Psicologia, lançando luz sobre os múltiplos atravessamentos no domínio da prática clínica. Seu objetivo foi problematizar a concepção de aprendizagem e ensaiar um movimento em defesa da invenção, da consideração dos fluxos heterogêneos e intensivos que operam incessantemente na experiência pessoal do psicólogo clínico. A partir do diálogo com as ideias novo-paradigmáticas de Humberto Maturana, percorremos também os trabalhos de Mony Elkaïm, no campo das terapias familiares, e sua interlocução com Gilles Deleuze e Félix Guattari. A pesquisa de campo consistiu na realização de um grupo de estudos com estudantes da graduação em Psicologia, tomado como um dispositivo de intervenção e conversações intersubjetivas coconstrutoras de novas e impensadas realidades: a consideração das singularidades e das diferenças que se sobrepõem ininterruptamente na prática e que nunca podem ser abarcadas por um conhecimento encerrado em definições absolutas e totalizantes.

This article discusses the academic background in Psychology, shedding light on the multiple crossings in the area of clinical practice. The aim of this study was to problematize the concept of learning and rehearse a movement in defense of the invention, the consideration of heterogeneous and intensive flows operating incessantly on personal experience of the clinical psychologist. From the dialogue with the new paradigmatic ideas of Humberto Maturana, we also cover the work of Mony Elkaïm, in the field of family therapies, and his interlocution with Gilles Deleuze and Félix Guattari. The field research consisted in a group of studies with graduate students in Psychology taked as a space for intersubjective conversations co-constructing of new and unthought realities: the consideration of singularities and differences that overlap uninterruptedly in practice and which can never be encompassed by a knowledge enclosed in absolute and totalizing definitions.

Este artículo discute la formación académica en Psicología, arrojando luz sobre los múltiples atravesamientos en el dominio de la práctica clínica. Su objetivo fue problematizar la concepción de aprendizaje y ensayar un movimiento en defensa de la invención, de la consideración de flujos heterogéneos y intensivos que operan incesantemente en la experiencia personal del psicólogo clínico. A partir del diálogo con ideas nuevo-paradigmáticas de Humberto Maturana, hemos recorrido también trabajos de Mony Elkaïm, en el contexto de las terapias familiares, y su interlocución con Gilles Deleuze y Félix Guattari. La investigación de campo consistió en la realización de un grupo de estudios con estudiantes graduandos en Psicología tomado como dispositivo de intervención y conversaciones intersubjetivas co-constructoras de nuevas y impensadas realidades: la consideración de singularidades y de diferencias que se superponen ininterrumpidamente en la práctica y que nunca pueden ser abarcadas por un conocimiento encerrado en definiciones absolutas y totalizantes.

Analysis on patent intelligence of COVID-19 prevention technology based on Regional Patent Information Dervice (Nanjing) Center / 中华医学科研管理杂志

Objective:This study analyzes COVID-19 prevention and treatment technology patents from 103 countries and regions worldwide, in order to have a good grasp of the most-current trends in COVID-19 prevention and treatment technology research worldwide, discuss the research directions of such technologies, provide theoretical foundations for interdisciplinary and multi-team cooperation.Methods:The retrieval strategies were constructed utilizing the retrieval and analysis system by the Regional Patent Information Service (Nanjing) Center of The State Intellectual Property Office and IncoPat's scientific and technological innovation platform, using third-level branches as the unit and separating the retrieval and proof processes, the queries built using IPC classification numbers and key words; the search was limited to invention patents, with utility models and designs excluded.Results:On February 14, 2020, there had been a total number of 136 087 invention patent applications for COVID-19 prevention and treatment technologies globally. In terms of the country of origin, the U. S. ranked first with 56 095 patents, followed by China (18 096). In terms of technical field, the top three were chemical therapeutic agents (47 634), vaccines (47 248) and diagnostic tests (12 991), with the U. S. possessing absolutely advantageous patent portfolios in all three fields. The applicants were mainly comprised of large enterprises abroad and universities and research institutes in China.Conclusions:China′s COVID-19 related patent applications are relatively scattered. In the field of chemotherapy, there is room for improvement compared with the advanced countries, and cooperation between scientific institutions and enterprises is insufficient. Therefore, China should further increase investment in chemical drug research and development and seize the opportunity to actively promote the research and development of vaccine technology. On the other hand, we need to consolidate the technical advantages and product advantages of epidemic prevention and control which are already accumulated, and strengthen the protection and layout of intellectual property rights. Furthermore, the technological innovation system combining production, education and research is the breakthrough point to encourage enterprises to become the subject of technological innovation.Last but not least, we should build a service platform for the transfer and transformation of scientific and technological achievements to enhance intellectual property rights and promote the transformation of scientific and technological achievements.

Discussion on emergency transfer of hospital service invention patent during COVID-19 pandemic period / 中华医学科研管理杂志

Objective:At present, there are several modes of patent transformation of hospital service invention in our country. However, most of them are one-to-one style which is time-consuming and difficult to achieve industrialization in a short time. This study focuses on whether it is appropriate for public hospitals to use the mode of general license (i.e. one patent licensed to several enterprises concurrently or successively) to turn the patents of invention into productivity more efficiently.Methods:Combined with the period of COVID-19 pandemic, Zhongshan Hospital Fudan University successfully applied the mode of general license to achieve the patent transfer experience, and discussed the important value of the mode of general license for translational medicine.Results:The latest achievements of medical research are turned into clinical medical technologies and products quickly and effectively, proposing an appropriate scheme for the rapid transformation of patents, which balanced the interest of different stakeholders to gain the win-win situation.Conclusions:The innovative general licensing model can enable the patents transformation quickly and efficiently as long as it′s used properly.

Compare outcome in patients of ileostomy and colostomy closure with surgical stapler versus ileostomy and colostomy closure with hand sewn anastomosis: a prospective study

Background: Diverting temporary stoma is created to protect the primary bowel pathology and distal anastomosis. Once that primary pathology has been overcome or distal anastomosis gets healed, closure of temporary stomas can be carried out. Invention of stapling devices for intestinal anastomosis provided another dimension than hand sewn method to the stoma closure techniques. In this study, we have compared two methods of loop stoma closure-hand sewn method versus stapler method.Methods: This is prospective comparative study in which 50 cases of loop ileostomy/colostomy were taken. 25 patients underwent ileostomy/colostomy closure by hand sewn anastomosis (group A). Another 25 patients underwent ileostomy/colostomy closure by stapler anastomosis (group B). Time taken for operation, initiation of oral intake, anastomotic leak, post-operative wound infection and total hospital stay duration were compared between these two groups to conclude about which method is superior and in the best interest of patient and surgeon.Results: Mean operation time 105.96 minutes (group A) and 72.84 minutes (group B). Mean time to start oral intake 5.36 days (group A), 3.6 days (group B). 16% patients (4/25) group A and 4% patients (1/25) group B developed anastomotic leak. 28% patients (7/25) group A and 8% patients (2/25) group B had post-operative wound infection. Mean hospital stay 10.4 days in group A and 7.84 days in group B.Conclusions: Stapler method provides significant benefits in terms of less operative time, early oral intake and less hospital stay. Overall stapler method for stoma closure is more efficient and cost effective.

Observatorio Métrico de Coronavirus de la Universidad de Pinar del Río, Cuba / Coronavirus Metric Observatory of the University of Pinar del Río, Cuba

El recurso más finito de un científico hoy es el tiempo. Un minuto sin una vacuna específica, un tratamiento adecuado o un protocolo seguro significa miles de muertes. A partir de esta necesidad, la presente investigación tuvo como objetivo caracterizar las funcionalidades del Observatorio Métrico de Coronavirus desarrollado por la Universidad de Pinar del Río Hermanos Saíz Montes de Oca como herramienta para el monitoreo, la compilación, el análisis y la visualización de la información procedente de artículos científicos arbitrados y de patentes de invención registradas en bases de datos internacionales sobre Coronavirus. Para su desarrollo se utilizaron diferentes métodos y procedimientos que permitieron, de conjunto con la tecnología aplicada y los indicadores métricos definidos, disponer de una plataforma dinámica que reduce significativamente los tiempos de búsqueda e interpretación de la información relevante sobre el dominio científico y tecnológico Coronavirus, lo que supone ser también un aporte oportuno y valioso que contribuye a la búsqueda de soluciones ante esta letal pandemia. Este Observatorio es un espacio de transformación de la información en conocimiento para la acción investigativa y la toma de decisiones. Es un resultado científico que contribuye al encadenamiento de la Academia con el sector investigativo y productivo de la Biotecnología en el país, conducido por los intereses y prioridades del Gobierno al servicio de toda la sociedad cubana(AU)

The finest resource for a scientist today is time. One minute without a specific vaccine, proper treatment, or a safe protocol means thousands of deaths. Based on this need, this research aims to show the functionalities of the Coronavirus Metric Observatory developed by the Pinar del Río University Hermanos Saíz Montes de Oca as a tool that allows the monitoring, compilation, analysis and visualization of information from peer-reviewed scientific papers and invention patents registered in international databases on Coronavirus. For its development, different methods and procedures were used that, together with the applied technology and the defined metric indicators, made it possible to have a dynamic platform that significantly reduces the search and interpretation times for relevant information on the scientific and technological domain Coronavirus. Having a dynamic platform that significantly reduces the time for analysis and interpretation of relevant information is also a timely and valuable contribution that contributes to the search for solutions to this deadly pandemic. This Observatory is a space for transforming information into knowledge for action. It is a scientific result that contributes to linking the Academy with the research and productive sector of Biotechnology in the country, driven by the interests and priorities of the Government at the service of all Cuban society(AU)

Invenção e estabilização: uma experiência com crianças autistas em dispositivos de Saúde Mental / Invention and stabilization: an experience with autistic children in Mental Health units / Invention et stabilisation: une expérience avec des enfants autistiques dans des dispositifs de Santé Mentale / Invención y estabilización: una experiencia con niños autistas en dispositivos de Salud Mental

O artigo aborda o valor do trabalho de invenção como forma de estabilização na clínica do autismo, a partir de um projeto de extensão universitária voltada a crianças em grave sofrimento psíquico, que tem a psicanálise como direção de trabalho e de tratamento. Durante esta vivência, podemos presenciar - a partir do acompanhamento do movimento dessas crianças - sujeitos que, por meio de suas manifestações particulares, buscavam produzir algo que estabilizasse sua desorganização psíquica. Assim, entende-se que o trabalho subjetivo implicado no ato da invenção - enquanto o ato que um sujeito realiza uma construção singular de elementos de sua história a partir de materiais já existentes - pode redundar numa estabilização e mediação com o campo do Outro por parte do sujeito, algo que foi possível observar nessa experiência clínica.

This article discusses the value of invention work as a form of stabilization in the clinic of autism. It is based on a university extension project aimed at children with severe psychic suffering in which psychoanalysis is used to guide work and treatment. Watching the movement of those children allowed us to single out subjects who, through their particular manifestations, sought to produce something that would stabilize their psychic disorganization. Therefore, we understand that the subjective work involved in the act of invention - as an act through which a subject performs a unique construction of elements of his history based on existing materials - may result in stabilization and mediation with the field of the Other by of the subject, which was observed in this clinical experience..

Cet article discute de la valeur du travail d'invention en tant que forme de stabilisation dans la clinique pour autistes, basé sur un projet d'extension universitaire destiné aux enfants souffrant de troubles psychiques sévères, dont la psychanalyse guide le travail et le traitement. Au cours de cette expérience, nous avons détecté - en suivant les mouvements de ces enfants - de sujets qui, par leurs manifestations particulières, cherchaient à produire quelque chose qui stabiliserait leur désorganisation psychique. Ainsi, il est entendu que le travail subjectif impliqué dans l'acte de l'invention - comme acte de construction unique d'éléments de l'histoire du sujet à partir de matériaux existants - peut aboutir à une stabilisation et à une médiation du champ de l'Autre de la part du sujet, ce qui a été observé dans cette expérience clinique..

El artículo discute el valor del trabajo de invención como forma de estabilización en la clínica del autismo, a partir de un proyecto de extensión universitaria dirigido a niños con graves trastornos psíquicos, que tiene al psicoanálisis como orientador del trabajo y del tratamiento. Durante esta experiencia, podemos presenciar - desde el seguimiento del movimiento de estos niños - sujetos que, a través de sus manifestaciones particulares, buscaron producir algo que estabilizara su desorganización psíquica. Por lo tanto, se entiende que el trabajo subjetivo involucrado en el acto de la invención - como el acto en el que un sujeto realiza una construcción única de elementos de su historia a partir de elementos existentes - puede resultar en una estabilización y mediación con el campo del Otro por parte del tema, algo que puede ser observado en esta experiencia clínica.

Analysis on Innovation Input-output in China ’s Pharmaceutical Enterprises from the Perspective of Patent Appli- cation / 中国药房

OBJECTIVE：To provide reference for optimizing resource allocation and precise investment of China ’s pharma- ceutical industry. METHODS ：The number of invention patent applications in China ’s pharmaceutical industry was searched from China Intellectual Property Netwerk ，and the status quo and structure of patent applications in China ’s pharmaceutical industry were analyzed. SPSS 23.0 software was used to analyze the input-output correlation of the number of invention patent applications with R&D investment and main business income of pharmaceutical enterprises in China. RESULTS ：The number of invention patent applications in China ’s pharmaceutical industry increased year by year. From 2000 to 2015，225 861 invention patents had been applied by domestic applicants and 43 149 invention patents had been applied by foreign applicants in China ；only 49.94％ domestic applicants applied for professional invention ，while 96.79％ of foreign applicants applied for professional invention. There was a positive correlation between the R&D expenditure of pharmaceutical enterprises and the number of invention patent applications，which indicated that the R&D investment of pharmaceutical industry in China was beneficial to the invention patent applications. The number of invention patent applications of pharmaceutical enterprises was also positively correlated with the main business income ，indicating that the increase of invention patent applications of pharmaceutical enterprises also effectively expanded the economic scale of pharmaceutical industry. CONCLUSIONS ：Compared with foreign countries ，the structure of patent applicants in domestic pharmaceutical industry needs to be adjusted urgently. Pharmaceutical enterprises have not yet become the main applicants. The continuous R&D investment of pharmaceutical enterprises effectively promotes the application of invention patent，expanded the economic scale of the pharmaceutical industry.

Research on distribution of invention patents of Chinese materia medica for treating high mortality diseases in China--analysis mechanism based on IPC number A61P / 中草药

Based on the International Patent Classification (IPC) A61P, this paper analyzes the distributional therapeutic situation of Chinese materia medica (CMM) in China dynamically and statically from the perspective of invention patent, then the list of 10 groups of A61P with the largest amount of invention patents application and effective amount is compared with the list of high mortality diseases in China, so as to verify the idea whether the R&D focus of CMM is on high mortality diseases, and put forward suggestions for the R&D directions and strategies of CMM in the treatment of high mortality diseases. The research finds that the R&D of CMM mainly focuses on treating high mortality diseases, except for the malignant tumors and mental disorders. In addition, the intellectual achievement of CMM in the treatment of digestive system diseases is the dominant direction. Under the background of internationalization and standardization of CMM, China needs to strengthen the R&D investment direction of CMM in the treatment of malignant tumors, mental disorders and other fields. The quantity and quality advantages of CMM in the treatment of digestive system diseases will be of significance, thus it needs to actively carry out patent distribution abroad. The role of technical evaluation in the cultivation of high-quality and high-value patents should be attached importance.

Patent Analysis of TCM for Treating Gastric Cancer in China Based on Patent Analysis and SWOT Model / 中国药房

OBJECTIVE：To provide reference for the R&D of TCM patents for treating gastric cancer and layout. METHODS：TCM patents for treating gastric cancer collected by the State Intellectual Property Office and the European Patent Office Espacenet were retrieved from the inception to Dec. 31st， 2019. After the initial examination ，a second search was conducted based on the keywords such as “Stomachache”“Fuliang” “Accumulation”“Cancer of stomach ”“Gastric”and their synonyms. Each literature was read one by one and screened manually. Excel 2007 software was used to input general information of included patents. SPSS modeler 15.0 software and SPSS 22.0 software were used for association rule analysis and hierarchical cluster analysis of TCM used more than 30 times and top 30 frequently used. Based on patent analysis ，internal strength （S），weakness（W），external opportunity （O）and threat （T）of TCM for treating gastric cancer were analyzed ；based on this ，four different types of combination strategies were formulated. RESULTS & CONCLUSIONS ：Finally，385 patents were obtained ，including 379 domestic patents （98.44％） and 6 foreign patents （1.56％）. The number of patent applications and applicants of TCM for treating gastric cancer in China was on the rise during 1994-2016. The commonly used TCM for treating gastric cancer were mainly tonifying deficiency drugs and heat clearing drugs ， and the meridian tropism were mostly the stomach meridian and spleen meridian. According to the efficacy ，the commonly used drug combinations include the combination of tonifying spleen and Qi ，the combination of anti-cancer and detoxification ，and the combination of drying dampness and resolving phlegm. The results of hierarchical cluster analysis showed that Poria cocos ， Atractylodes macrocephala ，Astragalus membranaceus ，Scutellaria barbata ，Hedyotis diffusa and Glycyrrhiza uralensis were clustered into one category and the common combination for treating gastric cancer. The remaining cluster distributions are also in line with the characteristics of TCM syndrome differentiation and treatment. Strength of domestic TCM patents for treating gastric cancer were that the number of patents in China was taking a leading position in the world ，the patent system of key applicants was mature，the combination of compound patents embodied the characteristics of disease and dialectical theory. Weakness included low patent authorization rate ，to-be-improved effectiveness and safety studies of TCM patents ，weak development of TCM extract patents，low degree of patent internationalization and hanging same-family patents. Opportunities were that the demand for drugs for gastric cancer was increasing with each passing day ，and natione actively support the development of the TCM industry. Threats were that competitors in the international market had the potential to seize the market. The development of TCM for treating gastric cancer in China should take market demand and national policy support as an opportunity ，learn from TCM patent characteristic system of key applicants ，continue to give full play to the advantages of TCM in prevention and syndrome differentiation of disease，pay more efforts to the development of weak links such as TCM extracts ，safety and effectiveness ，improve the international competitiveness in the field of patents ，while establish a warning and navigation analysis system for patents to effectively reduce the intellectual property threats and risks of invention patents of China in the international environment.

A chegada da adolescência para o autista: uma leitura psicanalítica / The arrival of adolescence for the autistic: a psychoanalytic reading / La llegada de la adolescencia para el autista: una lectura psicoanalítica

Este artigo tem como objetivo discutir a chegada da adolescência para o sujeito autista e as implicações advindas desse período da vida, tendo como referencial teórico a psicanálise. Conceitua inicialmente a adolescência. Num segundo momento, articula a adolescência do autista e o conceito de invenção. Para isso, lança mão dos conceitos da obra de Freud e de autores de orientação lacaniana, e utiliza-se do relato documental da história de Owen Suskind para abordar as particularidades da passagem pela adolescência desses sujeitos.

This article aims to discuss the arrival of adolescence for the autistic subject, and the implications arising from this period of life, having psychoanalysis as theoretical reference. Initially, adolescence is conceptualized. In a second moment, it articulates the autist’s adolescence and the concept of invention. In order to do so, it gets hold of the concepts of Freud-and-Lacan-oriented authors’ works and uses the documentary account of Owen Suskind’s history to address the particularities of their passage through adolescence.

Este artículo tiene como objetivo discutir la llegada de la adolescencia para el sujeto autista, y las implicaciones que surgen de ese periodo de la vida, teniendo el psicoanálisis como referencia teórica. Inicialmente, conceptualiza la adolescencia. En un segundo momento, articula la adolescencia autista y el concepto de invención. Para hacerlo, utiliza los conceptos de la obra de Freud y los autores de orientación lacaniana, y utiliza el relato documental de la historia de Owen Suskind para abordar las particularidades del paso por la adolescencia de estos temas.

Sobre el potencial subjetivante de las prácticas "psi". Cartografía de un dispositivo clínico con niños, niñas y adolescentes, en una favela de Rio de Janeiro / On the Subjective of "psi" practices. Cartography of a clinical device with children and teenagers from a favela in Rio de Janeiro / Sobre o potencial subjetivante das práticas "psi". Cartografia de um dispositivo clínico com crianças e adolescentes em uma favela do Rio de Janeiro

Resumen: El objetivo de este artículo es presentar una investigación realizada entre los años 2014 y 2018 en un dispositivo de abordaje clínico artístico, con niños y adolescentes de una favela de la ciudad de Rio de Janeiro. La investigación se realizó con el interés de estudiar las potencialidades de creación y transformación que las prácticas "psi" pueden albergar, en un dispositivo localizado y concreto. Se intentó describir y analizar las articulaciones que se produjeron en tanto el dispositivo intentaba llevar adelante su programa de acción, a partir de la estabilización de una controversia. El trabajo se enmarcó en los estudios sobre gubernamentalidad de Michel Foucault así como en el trabajo de Bruno Latour sobre la Teoría del Actor Red. Se utilizó una estrategia metodológica de inspiración cartográfica a partir de un trabajo de inmersión en el campo, acompañando los procesos que los actores del dispositivo fueron desplegando e intentando rastrear sus articulaciones y transformaciones. Se concluyó que el dispositivo investigado logró generar espacios de subjetivación singulares a partir de procesos de estabilización de las controversias que incluyen: el análisis de las afectaciones de los sujetos, en el encuentro con actores humanos y no humanos; el análisis de las controversias en términos de acontecimiento y el desarrollo de una perspectiva epistemológico-política, que posibilitó las transformaciones del dispositivo en función de los problemas que sus sujetos les presentaban.

Abstract: The objective of this paper is to present an investigation that was carried out in an artistic clinical approach with children and teenagers from a favela in the city of Rio de Janeiro between 2014 and 2018. The interest of the investigation was to study the creation and transformation potentialities that the "psi" practices might harbor inside a localized and concrete device. We tried to describe and analyze the articulations that were produced while the device was trying to carry on its action program from the stabilization of a controversy. The work was framed in the governmentality studies of Michel Foucault as well as in the work Actor-Network Theory of Bruno Latour. We used a methodological strategy of cartographic inspiration from a work of immersion in the field that accompanied the processes that the actors of the device were experiencing and trying to track their articulations and transformations. We concluded that the investigated device created singular areas of subjectivation based on processes of stabilization of the controversies that include: the analysis of the affects of subjects, in the gathering with human and non-human actors; the analysis of the controversies in terms of event and the development of an epistemological-political perspective that made possible the device transformations according to the problems that its subjects presented.

Resumo: O objetivo deste artigo é apresentar uma pesquisa realizada entre 2014 e 2018 em um dispositivo de abordagem clínico-artística com crianças e adolescentes de uma favela da cidade do Rio de Janeiro. A pesquisa foi realizada com o interesse de estudar as potencialidades de criação e transformação que as práticas "psi" podem abrigar, em um dispositivo localizado e concreto. Tentou-se descrever e analisar as articulações que ocorreram enquanto o dispositivo tentava realizar seu programa de ação, a partir da estabilização de uma controvérsia. O trabalho foi enquadrado nos estudos governamentais de Michel Foucault, bem como no trabalho de Bruno Latour sobre a Teoria do Ator da Rede. Foi utilizada uma estratégia metodológica de inspiração cartográfica a partir de um trabalho de imersão no campo, acompanhando os processos que os atores do dispositivo estavam implantando e tentando traçar suas articulações e transformações. Concluiu-se que o dispositivo investigado conseguiu gerar espaços singulares de subjetivação a partir de processos de estabilização das controvérsias que incluem: a análise das afetações dos sujeitos, no encontro com atores humanos e não humanos; a análise das controvérsias em termos de evento e o desenvolvimento de uma perspectiva epistemológico-política, que possibilitou as transformações do dispositivo em função dos problemas que seus sujeitos lhes apresentavam.

Effects of cardiac rehabilitation combined with psychological invention on clinical efficacy in high-risk patients with acute myocardial infarction after emergent percutaneous coronary intervention / 中华行为医学与脑科学杂志

Objective@#To investigate the effects of stage I cardiac rehabilitation combined with structural psychological invention high-risk patients with acute myocardial infarction (AMI) treated by emergent percutaneous coronary intervention (PCI).@*Methods@#Totally 120 patients with AMI that received emergent PCI were randomized into experimental group(n=60) and control group(n=60). The experimental group started stage I cardiac rehabilitation combined with structural psychological invention after emergency PCI.The control group received routine treatment.Self-rating Anxiety Scale (SAS) and Self-rating depression Scale (SDS) scores were compared in both groups at before PCI and 1 week after PCI.Left ventricular ejection fraction (LVEF) and left ventricular end-diastolic diameter (LVEDD) were compared in both groups at before PCI and 1 week, 1 month and 6 months after PCI.The incidence of adverse cardiac events including cardiac death and recurrence myocardial infarction were compared between the two groups at 6 months after PCI.@*Results@#The SAS score in the experimental group (36.38±5.15) was lower than that in the control group (42.10±5.79) in 1 week after PCI (t=2.313, P<0.05). The SDS score in the experimental group(37.09±5.56) was lower than that in the control group (43.85±5.33) in 1 week after PCI (t=2.330, P<0.05). The LVEF in the experimental group( (45.08±4.41)%) was significantly higher than that in the control group ((42.81±3.83)%) in 1 week after PCI ( t=2.209, P<0.05). The LVEF in the experimental group ((48.93±4.39)%) was significantly higher than that in the control group ((44.61±4.35)%) in 1 month after PCI (t=2.224, P<0.05). The LVEDD in the experimental group ((54.74±4.01)mm) was significantly lower than that in the control group ((57.81±4.49)mm) in 1 month after PCI (t=2.413, P<0.05). The LVEDD in the experimental group ((52.21±2.82)mm) was significantly lower than that in the control group ((55.65±3.88)mm) in 6 month after PCI (t=2.297, P<0.05). And there were no significant difference between the two groups at other time point(all P>0.05). The follow-up results after 6 months showed that the experimental group (8.9%) had lower incidence of cardiac death than that in the control group (24.1%) (HR(95%CI): 0.317(0.128-0.835), P<0.05). The follow-up results after 6 months showed that the experimental group (14.2%) had lower incidence of recurrence myocardial infarction than that in the control group (42.2%) (HR(95%CI): 0.263(0.125-0.548), P<0.05).@*Conclusion@#Stage I cardiac rehabilitation improved the cardiac function in high-risk patients with AMI treated by emergent PCI and reduced the incidence of cardiac death and recurrence myocardial infarction.

Por que arte e aprendizagem?: Por que aprendizagem e arte? Por que arte na formação do psicopedagogo? / Why art and learning?: Why learning and art? Why art in the formation of the psychopedagogue?

Neste texto, mostra-se o resultado de estudos e vivências a respeito do sistema simbólico e do processo de aprender, assim como do aprofundamento do papel da aprendizagem e da arte no desenvolvimento humano, apoiando-se na elaboração sobre a Aprendizagem Inventiva, proposta por Virgínia Kastrup. Destaca-se a necessidade de avançar na conceituação de aprendizagem como adaptação e propor a aprendizagem como invenção. Sendo assim, a cada momento, aprendizagem e arte deparam-se com o desconhecido e exigem do sujeito a lida com o inusitado, a invenção e a solução de problemas. Além disso, propõe-se a introdução da arte na formação do psicopedagogo, visando à apuração do olhar e da escuta, necessários para a observação e a intervenção psicopedagógicas. Apresenta-se, pois, um recorte de formação continuada realizada por meio do Grupo de Estudos Refletir, na qual os psicopedagogos estudam textos sobre o tema, ao mesmo tempo em que vivenciam a arte e pensam formas de intervenção junto aos seus aprendizes.

In this text, the result of studies and experiences regarding the symbolic system and the process of learning, as well as the deepening of learning and role of art in human development, leaning the elaboration on the Inventive Learning proposed by Virginia Kastrup. Highlights the need to advance in the concept of learning as adaptation and propose learning as invention. Thus, every moment, learning and art are faced with the unknown and require the subject to deal with the unusual, the invention and troubleshooting. In addition, it is proposed the introduction of art in psychopedagogue formation, aiming at determining the look and listen, necessary for observation and intervention of psychopedagogue. It presents a continuous formation held clipping through Grupo de Estudos Refletir, in which the psychopedagogues study texts on the subject, at the same time experience the art and think intervention forms together with his apprentices.