ABSTRACT
After percutaneous coronary intervention (PCI), the patient developed symptoms of pain, sensory impairment, paralysis, pallor of the skin, and pain during passive extension, and was diagnosed with PCI-induced antebrachial compartment syndrome. Since it was considered to be blood stasis and water stasis in Oriental medicine, we administered jidabokuippo and keishibukuryogan to the patient. Then the subjective and objective symptoms improved promptly, and the symptoms disappeared by the 10th day after the operation. The patient was able to discontinue jidabokuippo 14 days after the operation. It was suggested that the symptomatic treatment with Kampo medicine is effective for compartment syndrome.
ABSTRACT
We report a case of recurrent chronic subdural hematoma (CSDH) successfully treated with jidabokuippo. The patient was an 81 year-old woman who was performed burr hole surgery for left CSDH. Residual hematoma was gradually increased in postoperative serial brain CT. Although goreisan and saireito were administrated to prevent recurrence, the treatment was not effective. Thereafter, reoperation was performed because of the appearance of aphasia and right hemiparesis. Intraoperative findings revealed that the hematoma was viscous and was not enough drained. Since there was little improvement in clinical and CT findings, a phenomenon of the hematoma was considered as oketsu and jidabokuippo was administrated. Three weeks after the medication, right hemiparesis was improved. Seven weeks after the medication, the hematoma was markedly reduced. Taken together, these results strongly suggest that jidabokuippo is effective for postoperative recurrent CSDH which is difficult for drainage and has no response to the administration of goreisan and saireito.
ABSTRACT
A thirty-eight-year old woman with facial pain was diagnosed with trigeminal neuralgia, and treated with conventional carbamazepine therapy. Although the pain was alleviated to a certain degree, she visited our clinic to receive Kampo therapy. Judging from her facial injury in an accident thirty years ago, jidabokuippo was administered in addition to carbamazepine. The trigeminal neuralgia was then relieved, and Takagi's tender point in her abdomen was also reduced or disappeared. She could finally stop carbamazepine therapy. This case suggests that neuralgia patients with previous injury and Takagi's tender point can be treated with jidabokuippo.
ABSTRACT
<p>We reported a patient whose left hypochondrial pain disappeared after treatment with jidabokuippo and sokeikakketsuto. An 81-years-old woman developed pain after bruising for 2 months. Intercostal nerve block temporarily reduced the pain ; however, considerable pain subsequently remained. The patient received Jidabokuippo and Sokeikakketsuto. Seventeen days later, the patient was relieved from the prolonged pain and had melanotic defecation. This suggests that formulas classified for the treatment of potential blood stasis may relieve prolonged pain.</p>
ABSTRACT
<p>We evaluated the effect of jidabokuippo for postoperative finger swelling with a ring gauge. We recruited 112 patients who took jidabokuippo and 134 patients who did not take jidabokuippo after surgery of the upper extremities. Postoperative finger swelling was evaluated using a ring gauge. The size difference between affected and unaffected fingers was measured. The mean time to remission of swelling after surgery for traumatic/non-traumatic disorders was 4.3/2.2 weeks in the jidabokuippo group and 7.2/3.4 weeks in the nonjidabokuippo group. Time was significantly shorter in the jidabokuippo group. The size difference between affected and unaffected fingers at 1, 2, 4, 8, 12 weeks after traumatic/non-traumatic surgery was 0.9, 0.4, 0.3, 0.1, 0.1/0.4, 0.3, 0.3, 0.2, and 0.1 respectively in the jidabokuippo group and 3.3, 3.0, 2.1, 1.2, 0.8/1.2, 0.8, 0.4, 0.2, and 0.2 in the non-jidabokuippo group. The jidabokuippo group had significantly more robust remission effect in finger swelling (P < 0.01)</p>
ABSTRACT
We measured the level of derivatives of reactive oxygen metabolites (d-ROMs test) and total antioxidant capacity (OXY-adsorbent test) in adult volunteers and assessed whether jidabokuippo affects the oxidative stress regulation system. Twenty subjects received jidabokuippo 7.5 g/day, and the d-ROMs test and the OXY-adsorbent test were carried out 72 hours after taking the study drug. The subjects were also assigned to one of two groups : a Favorable response group (n = 6) or a Non-favorable response group (n = 14). The Favorable response group had improvement of such signs and symptoms as stiff shoulders, constipation, and bruises.No significant difference was observed in the d-ROMs test.However, the OXY-adsorbent test at 72 h was significantly lower than that at the pre-administration (p = 0.0290). No significant differences were observed in either the d-ROMs test or the OXY-adsorbent test in the favorable response group. On the other hand, the d-ROMs test and the OXY-adsorbent test at 72 h were significantly lower than those at pre-administration in the non-favorable response group (p = 0.0279, p = 0.0413, respectively). These results indicate that jidabokuippo affects the oxidative stress regulation system in human.
ABSTRACT
We measured the level of derivatives of reactive oxygen metabolites (d-ROMs test) and total antioxidant capacity (OXY-adsorbent test) in adult volunteers and assessed whether jidabokuippo affects the oxidative stress regulation system. Twenty subjects received jidabokuippo 7.5 g/day, and the d-ROMs test and the OXY-adsorbent test were carried out 72 hours after taking the study drug. The subjects were also assigned to one of two groups : a Favorable response group (n = 6) or a Non-favorable response group (n = 14). The Favorable response group had improvement of such signs and symptoms as stiff shoulders, constipation, and bruises. No significant difference was observed in the d-ROMs test. However, the OXY-adsorbent test at 72 h was significantly lower than that at the pre-administration (p = 0.0290). No significant differences were observed in either the d-ROMs test or the OXY-adsorbent test in the favorable response group. On the other hand, the d-ROMs test and the OXY-adsorbent test at 72 h were significantly lower than those at pre-administration in the non-favorable response group (p = 0.0279, p = 0.0413, respectively). These results indicate that jidabokuippo affects the oxidative stress regulation system in human.
ABSTRACT
We report a case of a man with lower extremity cellulitis, who had not responded to a two-week treatment with cefditoren, being successfully treated with Ji-daboku-ippo.<br>A 29-year-old man underwent an operation of the left knee six months earlier, and progress was good. However, his left lower extremity developed cellulitis. Cefditoren was administered, but it was not effective. We administered Ji-daboku-ippo, and his symptoms improved within three days and laboratory data improved within one week. We consider that therapy based on Kampo diagnosis is useful in the treatment of postoperative cellulitis on extremities.
ABSTRACT
In Kampo therapy for rheumatoid arthritis (RA), Keishi-ka-ryojutsubu-to, Keishini-eppi-itto and Keishi-shakuyaku-chimo-to are considered to be the primary formulas. However, it is often difficult to control arthritis with the primary formula alone. In this study, we administered 7.5g/day of Ji-daboku-ippo to 12 patients with RA, who had not responded sufficiently to the primary formula alone. Administration of the primary formula and other anti-rheumatoid drugs was also continued.<br>After three months of this supplemental administration of Ji-daboku-ippo, the mean±SE of the Lansbury's index significantly decreased from 45.3±5.8% to 33.3±3.8% (p<0. 01). After treatment for one year, a decrement in the Lensbury's index (of more than 20%) was seen in the four patients. These results suggest that supplemental administration of Ji-daboku-ippo is effective for patients who fail to respond sufficiently to the primary Kampo formulas used for RA.