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BACKGROUND@#The high rates of atopic dermatitis among children, treatment failures and treatment costs have created the search for new therapies to control flares of atopic dermatitis.@*OBJECTIVES@#We compared the efficacy and safety of topical essential oil (German Chamomile) versus topical steroids (hydrocortisone 1%) in controlling flares of atopic dermatitis.@*METHOD@#We randomly selected 60 children diagnosed of AD or children that qualified to the criteria of AD. They we’re randomly grouped into three. Twenty for Essential Oil (EO) group, twenty for Steroid group (SG) and Twenty for placebo (distilled water) group. They were advised to apply medicine kept in uniform brown plastic bottles 3x a day for 4 weeks. Data were recorded weekly using the EASI (Eczema Score Index) scoring. Other topical medications such as emollients and moisturizers were continued.@*RESULTS@#At week 4 control of flaring was achieved; 42% for EO group and 55% for steroid group. The differences in treatment effects were not statistically significant.@*CONCLUSION@#Essential oil was comparable in cure rate to mild topical steroid. Essential oil can be safe and affordable. However further study in a wider scale is recommended.
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EczemaABSTRACT
Aims: This study aims to evaluate the five clones of jojoba plant under the influence of irrigation intervals and the impact on growth and yield of chemical content. Study Design: Two field experiments were carried out for five clones (S-L, S-610, S- 700, S-B and S-G), to study the effect of irrigation intervals; one week (control), two weeks and three weeks) on jojoba plants at aged three and thirteen years from planting to investigation growth, yield characters and content seed from oil and some chemical contents. Place and Duration of Study: Almaghara Research and Production Station (latitude: 30,717993''N, longitude: 33, 329103 E) which follow Desert Research Center, Agriculture Ministry, Egypt, at 2015l2016 and 2016/2017 respectively. Methodology: The experimental rows (5 plants) were assigned for each clone in three replications. The farming distances were 4 x 2 meters. Mixed seedlings of both females and males were planted at a rate of one male seedling for every six female seedlings to allow cross-fertilization of each clone. All clones were treatment at three times (October, March and April). The plants were collected on 22nd April to determine the growth, yield characters and some chemical content. Statistical analyses and mean comparisons were conducted using MSTATC software. Results: The jojoba plant was affected by increased irrigation interval, and it was clear in all clones. Irrigation every three weeks had an impact of irrigation every week. The effect of irrigation interval varied from one clone to another and the lowest was s-700. The older seedlings are less affected by irrigation interval than small seedlings. The best results were category s-700 at the age of thirteen years and irrigation every two weeks. Conclusion: All variable of studied confirmed that clones of jojoba had a significant effect with irrigation interval at one week but decrease value at three weeks. Jojoba plants tolerance to water stress but irrigation interval every week increased seed yield.
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Jojoba(the plant belonging to Simmondsiaceae)seeds are not only a kind of global special oil resources but also a type of good folk medicines because they are riched in jojoba oil and simmondsin and have many pharmacological effects such as anti-inflammatory effect,food inhibitor and promoting-antibiosis. The paper reviews the studies on jojoba chemical compositim, extraction and purification,detection and analysis methods,pharmacological activity and dosage development,in order to provide reference for further research and application.
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Objective: To isolate and identify chemical constituents with antioxidant and lipoxygenase inhibitory effects of the ethanolic extract of Simmondsia chinensis (Jojoba) leaves. Methods: The alcoholic extract was subjected to successive solvent fractionation. The antioxidant active fractions (chloroform, ethyl acetate and aqueous fractions) were subjected to a combination of different chromatographic techniques guided by the antioxidant assay with DPPH. The structures of the isolated compounds were elucidated on the basis of spectroscopic evidences and correlated with known compounds. The antioxidant activity was assessed quantitively using DPPH and β-carotene methods. The inhibitory potential against enzyme lipoxygenase was assessed on soybean lipoxygenase enzyme. Results: Ten flavonoids and four lignans were isolated. Flavonoid aglycones showed stronger antioxidant and lipoxygenase inhibitory effects than their glycosides. Lignoid glycosides showed moderate to weak antioxidant and lipoxygenase inhibitory effects. Conclusions: A total of 14 compounds were isolated and identified from Simmondsia chinensis; 12 of them were isolated for the first time. This is the first report that highlights deeply on the phenolic content of jojoba and their potential biological activities and shows the importance of this plant as a good source of phenolics in particular the flavonoid content.
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OBJECTIVE@#To isolate and identify chemical constituents with antioxidant and lipoxygenase inhibitory effects of the ethanolic extract of Simmondsia chinensis (Jojoba) leaves.@*METHODS@#The alcoholic extract was subjected to successive solvent fractionation. The antioxidant active fractions (chloroform, ethyl acetate and aqueous fractions) were subjected to a combination of different chromatographic techniques guided by the antioxidant assay with DPPH. The structures of the isolated compounds were elucidated on the basis of spectroscopic evidences and correlated with known compounds. The antioxidant activity was assessed quantitively using DPPH and β-carotene methods. The inhibitory potential against enzyme lipoxygenase was assessed on soybean lipoxygenase enzyme.@*RESULTS@#Ten flavonoids and four lignans were isolated. Flavonoid aglycones showed stronger antioxidant and lipoxygenase inhibitory effects than their glycosides. Lignoid glycosides showed moderate to weak antioxidant and lipoxygenase inhibitory effects.@*CONCLUSIONS@#A total of 14 compounds were isolated and identified from Simmondsia chinensis; 12 of them were isolated for the first time. This is the first report that highlights deeply on the phenolic content of jojoba and their potential biological activities and shows the importance of this plant as a good source of phenolics in particular the flavonoid content.
ABSTRACT
Jojoba (the plant belonging to Simmondsiaceae) seeds are not only a kind of global special oil resources but also a type of good folk medicines because they are riched in jojoba oil and simmondsin and have many pharmacological effects such as anti-inflammatory effect, food inhibitor and promoting-antibiosis. The paper reviews the studies on jojoba chemical compositim,extraction and purification,detection and analysis methods, pharmacological activity and dosage development, in order to provide reference for further research and application.
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The present review paper aims to highlight the effects of extracts of genus zizyphus for the treatment of Diabetes clinically throughout the world. The basic aim is to study the hyperglycemic effect of this genus and its use. So as the effect of herbal medicine is more friendly then synthetic medicines. The effects of three species Ziziphus spinacristi, Zizyphus jojoba, and Zizyphus vulgaris have been studied clinically and have great effect on insulin secretion. While work on Zizyphus maritiana have also been done. It is concluded that genus zizyphus have potential of antidiabetic activity. Many species of Zizyphus grow widely. As natural drugs are with no or less side effects and safe for human health so they can greatly replace synthetic drugs in the forth coming future.