Ten Cases of Rosacea Successfully Treated / 日本東洋医学雑誌

Rosacea begins with recurrent episodes of blushing that eventually become persistent dark facial erythema. Its etiology is still unknown, and no curative therapy has been established. We successfully treated 10 middle-aged female patients with several Kampo formulas. Ages of the patients ranged from 46 to 81 years old (average 60.6 years old). Periods from disease onset to the beginning of therapy were1month to 6 years (average 2.2 years). The Kampo formulas used were daisaikoto with orengedokuto in 7 cases, and kakkonkokato in 3 cases. All patients healed within 14 months. We thus recommended daisaikoto with orengedokuto, or kakkonkokato as a first choice for the treatment of rosacea.

Three Cases of Refractory Facial Eruption Successfully Treated with Kakkonkokato / 日本東洋医学雑誌

Kakkonkokato is a special formula used for the treatment of rosacea-like dermatitis lesions in the nasal region, but very few cases treated with this formulation have been reported so far. Here, we report three patients with refractory facial eruptions of rosacea-like dermatitis treated successfully with kakkonkokato. Case1was a 39-year-old man who presented with a 15-year history of rosacea-like dermatitis lesions in the nasal region. After 3 weeks' treatment with kakkonkokato, a marked improvement of his lesions was seen, with disappearance of the redness of his face. Case 2 was a 56-year-old woman who presented with a prolonged history of itchy eruptions around her mouth and nasal region. After 8 weeks' treatment with kakkonkokato, an almost complete disappearance of her eruptions was observed. Case 3 was a 26-year-old woman who presented with atopic dermatitis and intractable erythema under her nose, which was refractory to treatment with steroid ointments and antiallergic agents. After 2 months' treatment with kakkonkokato, her erythema completely resolved, along with improvement of the systemic lesions of atopic dermatitis. The observations in these three cases suggest that kakkonkokato may be a useful formula for the treatment of not only rosacea-like dermatitis in the nasal region, but also of refractory facial eruptions of other causes.