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@#AIM: To investigate the best time for indwelling catheter of patients with chronic dacryocystitis after lacrimal drainage tube implantation.<p>METHODS: Totally 143 eyes of 143 patients with chronic dacryocystitis after lacrimal drainage tube implantation were selected in our hospital. They were divided into 3 groups including group A(50 eyes of 50 cases)with indwelling catheter in 9wk after tube implantation, group B(57 eyes of 57 cases)with indwelling catheter in 12wk after tube implantation, and group C(36 eyes of 36 cases)with indwelling catheter in 6wk after tube implantation. The clinical efficacy, visual acuity, incidence of epiphora, recurrence rate and incidence of postoperative complications with followed-up among three groups were compared.<p>RESULTS: On the day of extubation, the total effective rates of the three groups were 94%, 93% and 39%, the difference was statistically significant(<i>P</i><0.0167). The total effective rates of group A and group B were better than those of group C, and the difference was statistically significant(χ2=30.830, 32.056, <i>P</i><0.001). At 3mo after extubation, the total effective rates of the three groups were 56%, 51% and 36%, there was no significant difference(χ2=3.454, <i>P</i>=0.178). At 3mo after extubation, there was no significant difference in the visual acuity and the incidence of epiphora among the three groups(<i>P</i>>0.05). At 6mo after extubation, the recurrence rates of the three groups showed no significantly different(<i>P</i>=0.056). The incidence of postoperative complications in three groups were 4%(2/50), 7%(4/57)and 25%(9/36), the difference was statistically significant(χ2=11.048, <i>P</i>=0.004). The incidence of postoperative complications in group C was higher than that in groups A and B(χ2=6.499, 5.934; <i>P</i>=0.011, 0.015).<p>CONCLUSION: The clinical benefits of 6wk and 9wk after lacrimal drainage tube implantation are better than that of 12wk.
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@#AIM: To explore the application effect of mitomycin C in lacrimal duct obstruction during anterograde lacrimal drainage tube implantation. <p>METHODS:Totally 78 cases of lacrimal duct obstruction(82 eyes)were randomly divided into the observation group(39 cases, 42 eyes)and the control group(39 cases, 40 eyes), and the control group was treated with lacrimal drainage tube implantation. The observation group was based on this combined mitomycin C treatment and compared the effect of two groups. <p>RESULTS: The total effective rate of the observation group was 81%, which was significantly higher than that of the control group(62%), and the difference between the two groups was statistically significant(<i>P</i><0.05). The eye surface change score(26.25±1.67)and tear SP content(256.32±10.07pg/mL)were lower than that of the control group after treatment. The tear film rupture time(8.85±0.89s)was shorter than that of the control group(9.58±0.92s), and the two groups were statistically significant(<i>P</i><0.05). <p>CONCLUSION: Mitomycin C can improve the efficacy of anterograde lacrimal drainage tube implantation for the treatment of lacrimal duct obstruction and improve prognosis.
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@#AIM: To observe the clinical effect of the neotype lacrimal drainage tube(RS model)for the treatment of lacrimal duct obstruction.<p>METHODS: It was a retrospective case series study. Totally 75 cases(93 eyes)of lacrimal duct obstruction were enrolled in the study and randomly divided into two groups: treatment group(50 eyes)and control group(43 eyes). The treatment group was implanted the neotype lacrimal drainage tube(RS model). The control group underwent the implantation of annular silicone tube and their efficacy were analyzed. <p>RESULTS: Followed up for 3-12mo after extubation, the cure rate and total effective rate of the treatment group were 90%, 96% respectively, and the control group of it were 72%, 84%.The difference between the two groups was statistically significant(<i>P</i><0.05). The total rate of intraoperative and postoperative complications was 8% in treatment group, 35% in control group respectively, the rate of the control group was obviously higher than that of the treatment group, there was significant statistical difference between the two groups(<i>P</i><0.05). <p>CONCLUSION: The implantation of the neotype lacrimal drainage tube(RS model)is safe,fast and simple, easy to operate and extubate easily with good clinical effect in the treatment of lacrimal duct occlusion.