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@#AIM: To explore the effect of lacrimal duct probing combined with tobramycin and dexamethasone ophthalmic ointment on ocular surface symptoms and quality of life of patients with lacrimal duct obstruction.<p>METHODS: A total of 120 patients(120 eyes)with lacrimal duct obstruction treated in the hospital from October 2016 to January 2018 were selected. They were randomly divided into control group(<i>n</i>=60)and observation group(<i>n</i>=60)according to the treatment methods. The control group was treated with simple lacrimal duct probing while the observation group was treated with lacrimal duct probing combined with illing with tobramycin and dexamethasone. The clinical efficacy, changes in ocular surface disease index(OSDI)score, levels of serum high-sensitivity C-reactive protein(hs-CRP)and procalcitonin(PCT)before and after treatment were compared between the two groups.<p>RESULTS: The clinical efficacy in observation group was significantly better than that in control group(<i>P</i><0.05). The total score of OSDI, scores of the frequency of eye discomfort, the effect of eye discomfort on daily life and the frequency of eye discomfort caused by adverse environment in the observation group were significantly decreased after treatment(<i>P</i><0.05). The levels of serum hs-CRP and PCT in the observation group were significantly lower than those in the control group after treatment(<i>P</i><0.05).<p>CONCLUSION: Lacrimal duct probing combined with tobramycin and dexamethasone is markedly effective in the treatment of lacrimal duct obstruction. It can effectively relieve the ocular surface symptoms and improve quality of life of patients.
ABSTRACT
@#AIM: To explore the effect of lacrimal duct probing combined with tobramycin and dexamethasone ophthalmic ointment on ocular surface symptoms and quality of life of patients with lacrimal duct obstruction.<p>METHODS: A total of 120 patients(120 eyes)with lacrimal duct obstruction treated in the hospital from October 2016 to January 2018 were selected. They were randomly divided into control group(<i>n</i>=60)and observation group(<i>n</i>=60)according to the treatment methods. The control group was treated with simple lacrimal duct probing while the observation group was treated with lacrimal duct probing combined with illing with tobramycin and dexamethasone. The clinical efficacy, changes in ocular surface disease index(OSDI)score, levels of serum high-sensitivity C-reactive protein(hs-CRP)and procalcitonin(PCT)before and after treatment were compared between the two groups.<p>RESULTS: The clinical efficacy in observation group was significantly better than that in control group(<i>P</i><0.05). The total score of OSDI, scores of the frequency of eye discomfort, the effect of eye discomfort on daily life and the frequency of eye discomfort caused by adverse environment in the observation group were significantly decreased after treatment(<i>P</i><0.05). The levels of serum hs-CRP and PCT in the observation group were significantly lower than those in the control group after treatment(<i>P</i><0.05).<p>CONCLUSION: Lacrimal duct probing combined with tobramycin and dexamethasone is markedly effective in the treatment of lacrimal duct obstruction. It can effectively relieve the ocular surface symptoms and improve quality of life of patients.
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AIM: To explore the treatment method and timing for neonatal dacryocystitis in different month-old children. ●METHODS: A total of 180 children ( 207 eyes ) with dacryocystitis who were admitted to our hospital between Jan. 2010 and Dec. 2014 were selected as the study subjects. According to months of age, they were divided into ●RESULTS:1) Hasner valvular obstruction was common in different months old children, and the proportion was higher than that of children with nasolacrimal duct bony part obstruction (P0. 05);5) the times of treatment in 3-6 months old group and 6-12 months old group was more than that in ● CONCLUSION: For < 3 months old children with dacryocystitis, conservative treatment like lacrimal massage should be preferred. For children without effect, lacrimal duct washing with pressure and lacrimal duct probing should be given; For 3-6 months old children, lacrimal duct washing with pressure is preferred, and for 6 - 12 months old children, lacrimal duct probing is recommended.
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PURPOSE: To evaluate clinical outcomes of silicone tube intubation according to the site of resistance to lacrimal duct probing in complete or partial nasolacrimal duct obstruction patients. METHODS: This study included 102 eyes of 72 patients who were diagnosed with complete or partial nasolacrimal duct obstruction and who underwent silicone tube intubation. According to the site of resistant to nasolacrimal duct probing, eyes were divided into proximal resistance (Group I), distal resistance (Group II) and both side resistance (Group III). The success rate was estimated based on functional (symptom relief) and anatomical (normalization of tear meniscus) success. RESULTS: The success rates in Group I, Group II, and Group III were 53.1%, 78.8%, and 27.0%, respectively, showing that Group II attained the highest success rate (Pearson chi-square test, p = 0.001). CONCLUSIONS: In cases of only distal resistance to lacrimal probing without dacryocystography, silicone tube intubation should be performed with expectation of good clinical outcomes, even if complete nasolacrimal obstruction was suspected on syringing.
Subject(s)
Humans , Intubation , Nasolacrimal Duct , SiliconesABSTRACT
PURPOSE: To evaluate clinical outcomes of silicone tube intubation according to the site of resistance to lacrimal duct probing in complete or partial nasolacrimal duct obstruction patients. METHODS: This study included 102 eyes of 72 patients who were diagnosed with complete or partial nasolacrimal duct obstruction and who underwent silicone tube intubation. According to the site of resistant to nasolacrimal duct probing, eyes were divided into proximal resistance (Group I), distal resistance (Group II) and both side resistance (Group III). The success rate was estimated based on functional (symptom relief) and anatomical (normalization of tear meniscus) success. RESULTS: The success rates in Group I, Group II, and Group III were 53.1%, 78.8%, and 27.0%, respectively, showing that Group II attained the highest success rate (Pearson chi-square test, p = 0.001). CONCLUSIONS: In cases of only distal resistance to lacrimal probing without dacryocystography, silicone tube intubation should be performed with expectation of good clinical outcomes, even if complete nasolacrimal obstruction was suspected on syringing.