ABSTRACT
OBJECTIVE: Our aim was to report an effective procedure of injection of large amount of diluted vasopressin in the treatment of interstitial pregnancy using endoscopic cornuotomy METHODS: This is an uncontrolled retrospective study of 17 patients interstitial pregnancies treated of by endoscopic cornuotomy from June 2001 to June 2004 in our hospital. All cases were applied by the large amount of diluted vasopressin injection. RESULTS: Among 446 ectopic pregnancies, interstitial pregnancies were 17 (3.81%). Fourteen patients (82.4%) were unruptured, three patients (17.6%) were ruptured. Mean (+/-SD) age and parity of patients were 35.6+/-3.9 years (range 30-40 years), 1.5+/-2.1 (range 0-3), respectively. At the time of operation the duration of amenorrhea and mean size of ectopic gestation were 54.5+/-9.6 day and 2.6 x 2.6 cm, respectively. The amount of injected vasopressin was 190.0+/-55.5 cc. For the cornual closure, the endosuture method was applied in 10 patients (59%), and the endoloop method was applied in 7 patients (41%) The mean (+/-SD) blood loss and operation time were 18.2+/-15.9 cc and 28.3+/-7.8 minute, respectively. In fifteen patients (88%), serum beta-hCG level from the preoperative base was declined 90% or more within postoperative day 4 and in 2 patients (12%), it was decreased within postoperative day 60. CONCLUSION: Endoscopic cornuotomy using the large amount of diluted vasopressin injection procedure is a safe and effective in the interstitial pregnancy.