ABSTRACT
In this study, we sought to describe a novel imaging apparatus that is lightweight, inexpensive, and highly eff ective for use in colorectal diagnostic and treatment settings. Typical probes for use in colorectal ultrasonic imaging applications are developed for surgeons to diagnose and stage rectal tumors and image the rectum and anus. Here we outline a new technique and use it for colorectal imaging in an animal. This technique involves use of an ultrasound array module positioned along the axis of rotation such that improved rotation is possible. This module is in the shape of a linear rod with a rotary linear component that allows for emission of focused ultrasonic echo signals from a linear section of the probe. The usability of the transducer and rectal image quality are satisfactory in a porcine model with the technique proposed here, axial/lateral resolution as 0.96/2.24 mm with 6 dB applied through the contour map using the point spread function. When compared to currently available methods, this technique provides superior diagnostic 3D volumetric image quality with reduced acquisition time. Given this, the ultrasound device proposed here may prove a viable and preferable method to those currently available for urology and colorectal imaging applications.
Subject(s)
Animals , Anal Canal , Methods , Rectal Neoplasms , Rectum , Surgeons , Transducers , Ultrasonics , Ultrasonography , UrologyABSTRACT
Objective To establish an optimal linear probe recovery correction method for in vivo and in vitro cyclophosphamide. Methods with ringer solution as the perfusion, retrodialysis gain and loss method were used to calibrate the linear probe. The impact of different perfusion flow rates on microdialysis relative recovery for cyclophosphamide was investigated by HPLC-MS/MS. Results When the perfusion was 1.0μl/min, in vitro recovery results were in the range of (24.11±1.75)%to (50.93±0.91)%for the gain method, and(26.19±0.76)% to(53.31±1.23)% for the loss method;recovery results in vivo were(26.19±0.76)%. Conclusion Cyclophosphamide is suitable for microdialysis sampling. This experiment calibration method is simple and effective.
ABSTRACT
Objective To establish an optimal linear probe recovery correction method for in vivo and in vitro cyclophosphamide. Methods with ringer solution as the perfusion, retrodialysis gain and loss method were used to calibrate the linear probe. The impact of different perfusion flow rates on microdialysis relative recovery for cyclophosphamide was investigated by HPLC-MS/MS. Results When the perfusion was 1.0μl/min, in vitro recovery results were in the range of (24.11±1.75)% to (50.93±0.91)% for the gain method, and (26.19 ±0.76)% to(53.31 ±1.23)% for the loss method; recovery results in vivo were (26.19±0.76)%. Conclusion Cyclophosphamide is suitable for microdialysis sampling. This experiment calibration method is simple and effective.
ABSTRACT
Transabdominal scan of seminal vesicles with combined use of electronic linear probe and mechanical sector scanner was performed on normal adults and patients with seminal vesicular disease. The images of seminal vesicles were demonstrated easily through the multidirectional and multirotational handling of the scanners on the lower abdomen. The Ultrasonographic interpretation of the size, shape and contour of seminal vesicles together with the display of the internal structures within seminal vesicles was proved to be useful in the diagnosis of seminal vesicular diseases, particularly in the screening of underlying lesions of patients with hematospermia. The method is simple, atraumatic, and requires no special apparatus. It is concluded that the method is useful for the screening examination of seminal vesicular diseases.