Efficacy of fine needle aspiration cytology in Head and Neck lesions.

Background: A perplexing diagnostic and therapeutic dilemma is often presented by masses involving glandular and nodal structures of head and neck - lymph nodes, thyroid gland and salivary glands. Fine needle aspiration of such masses is a rapid, direct and safe adjunctive surgical procedure for obtaining material for cytologic analysis. Objectives: To study the diagnostic efficacy of FNAC in the head and neck lesions and correlate it with histopathology. Material & Methods: It is a study of 289 cases of head and neck area referred to the Department of Pathology, Govt. Medical College Patiala. The cytological diagnosis was compared with histopathology. The false positive/negative data was analysed to calculate the sensitivity, specificity, positive predictive value, negative predictive value and overall diagnostic accuracy of the study. Results: The study included 289 cases between 1-70 years in which 59.86% were females and 40.13% were males. Maximum cases were in the age group of 21-30 years. Maximum numbers of cases were from lymph nodes, 139 (48.09%). The overall accuracy was 96.53% with sensitivity of 91.54% and specificity of 98.16%. Positive and negative predictive values were 94.20% and 97.27% respectively. Conclusion: FNAC is an excellent first line method for investigating the nature of palpable lesions in the head and neck region. It can obviate the need for surgery if the lesion is non-neoplastic.

MR Diffusion-Weighted Imaging and ADC Value Measurement in the Diagnosis of Breast Axillary Lymph Node Cancer / 医疗卫生装备

Objective To value diffusion-weighted imaging and ADC value measurement of benign and malignant axillary lymph node identification value. Methods From 2006-06 to 2008--02, by collecting in the hospital for breast dynamic con-trast-enhanced scans and diffusion-weighted imaging, 217 lesions in 56 cases with a clear outcome of the surgery and pathology and/or needle biopsy results were retrospectively analyzed.Results The DWI could accurately show the lymph node of the armpit abnormality, 163 cases of 47 breast cancer cases with lymph node metastasis showed high signal in DWI image that did not decrease with increasing b value, similar to the 54 cases of 9 benign enlarged responsive prolifer-ative lymph nodes. But the former showed higher signal than the later. The ADC values were(1.017±0.114)×10-3mm2/s and (1.905±0.136)×10-3mm2/s respectively, and showed significant difference between two groups (P<0.05). Conclusion The dynamic contrast-enhanced subtraction MR technology benign and malignant breast lesions has high diagnosis and differ-ential diagnosis importance. DWI and ADC value measurement is a safe, non-invasive, accurate and rapid diagnosis of metastasis axillary lymph nodes and benign proliferative response of the lymph nodes means.