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Objective:To explore the effect of low frequency magnetic stimulation on myelin and inflammation in the callosum of demyelinated mice.Methods:Thirty-six 6 to 8-week-old male C57BL/6J mice were randomly divided into a control group, a cuprizone (CPZ) group and a magnetic therapy group. The CPZ group and the magnetic therapy group had demyelination induced by feeding a mixed diet containing 0.3% CPZ for 6 weeks, while the control group was given conventional food. The magnetic therapy group was given 50Hz 10mT magnetic stimulation during the 6 weeks for 20min daily, 5 days a week. The body mass of each mouse was observed every 7 days. At the end of the 6th week elevated cross maze experiments were conducted to observe any anxiety state. The myelin sheath in the corpus callosum was observed using Luxol fast blue staining and myelin basic protein (MBP) immunohistochemistry Tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) in the corpus callosum were detected using enzyme-linked immunosorbent assays.Results:After the 6 weeks of treatment, the average body mass of the mice in the magnetic therapy group had improved significantly compared with the CPZ group. The CPZ group′s times in the elevated cross maze experiments were significantly shorter than those of the control group and also shorter than those of the magnetic therapy group. The Luxol staining showed significant myelin loss in the corpus callosum of the CPZ group, but compared with the CPZ group the average loss of myelin in the magnetic therapy group was significantly less. This was further confirmed by the MBP immunohistochemistry. Compared with the control group, the average expression of MBP in the CPZ group was significantly reduced, while in the magnetic therapy group it was significantly increased. Compared with the control group, the average TNF-α and IL-1β levels in the corpus callosum of the CPZ group increased significantly, but compared with the CPZ group the average levels in the magnetic therapy group had decreased significantly.Conclusions:Low frequency magnetic stimulation improves the body weight and anxiety state of mice. That is probably related to less myelin loss and inhibited inflammatory response in the corpus callosum.
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Objective To observe the effects of mind-regulating brain-developing acupoint magnetic therapy in patients with mild cogni-tive impairment (MCI). Methods From May to October, 2015, 60 patients with MCI were randomly divided into control group (n=30) and observation group (n=30). The control group received magnetic therapy on Yangming meridians, and the observation group received magnet-ic therapy on mind-regulating brain-developing acupoints, for two months. They were assessed with Montreal Cognitive Assessment (Mo-CA), digit-span and digit symbol of Wechsler Adult Intelligence Scale (WAIS). Results After treatment, the scores of MoCA, digit-span and digit symbol of WAIS significantly increased in the observation group (t>4.858, P2.188, P5.527, P2.324, P2.262, P0.05). Conclusion Magnetic therapy on acupoints related with cognition could improve the cognitive function in patients with MCI.
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Objective To observe the effect of acupoint magnetic therapy on coronary heart disease.Methods 80 patients with coronary heart disease were divided into treatment group( n =40) and control group( n =40).The treatment group was treated with acupoint magnetic therapy on the basis of conventional treatment,and the control group with conventional treatment.Clinical therapeutic effect,the scores of traditional Chinese medicine symptom were observed.Results There was significant difference between the two groups in the total effective rate and the scores of traditional Chinese medicine symptom[90.0％ vs 72.5％,(13.25 ± 3.68 ) vs (15.18 ± 4.16),all P ＜0.05].Conclusion Acupoint magnetic therapy for treatment of coronary heart disease has an obvious therapeutic effect.
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O uso de campos eletromagnéticos pulsados (CEMP) é uma das terapias frequentemente utilizadas pelo fisioterapeuta para tratamento de seus pacientes com diferentes patologias e em diversos países, exceto no Brasil. Devido ao longo tempo de utilização em todos os continentes e a quantidade de publicações existentes sobre o tema, busca-se compreender o motivo de essa técnica não estar presente na rotina de tratamento das clínicas de fisioterapia brasileiras. Para tentar responder a essa questão, realizou-se uma revisão sistemática na base de dados do Pubmed, de 1968 a 2010 (42 anos), com as palavras-chave ?PEMF? e ?Pulsed Electromagnetic Fields?, encontrando-se, respectivamente, 274 e 899 resultados. Após esse levantamento, foram selecionados 36 artigos do período de 1981 a 2008 hand made, além de consulta a 6 livros. Após a coleta de dados, perceberam-se resultados positivos no tecido ósseo, em relação à consolidação de fraturas e a osteoporose, devido à sua ação piezoelétrica. Os efeitos antiinflamatórios e regenerativos também são citados. Portanto, o conhecimento desse recurso no Brasil deve ser despertado em todos os profissionais de saúde que compõem as equipes multidisciplinares de assistência, para que o tratamento possa fazer parte da rotina de trabalho dos fisioterapeutas, beneficiando pacientes de todas as faixas etárias e portadores de diferentes problemas. Sugere-se a fabricação de aparelhos geradores de PEMF por empresas nacionais para diminuir custos e facilitar o acesso a esse agente físico.
The use of pulsed electromagnetic s (PEMF) is one of the therapies frequently used by physiotherapists for treating different patients? pathologies in several countries, with exception of Brazil. Due to the long time of its use in all continents and the numerous publications on this subject, the reason why this technique is not present in the routine of Brazilian physiotherapy clinics should be analyzed. In order to answer this question, a systematic review on the Pubmed data was performed, considering the period from 1968 to 2010 (42 years), with the keywords ?PEMF? and ?Pulsed Electromagnetic Fields?, yielding, respectively, 274 and 899 results. After this survey, additional 36 articles within the period from 1981 to 2008 were selected on a hand madeapproach, besides the research in 6 books. Following data collection, positive results were verified on bone tissue, regarding fracture consolidation, and osteoporosis, due to piezoelectric action. Anti-inflammatory and regenerative effects were also cited. Therefore, the knowledge of this resource in Brazil should be awakened in all health professionals from multidisciplinary assistance teams, so the treatment can be part of physiotherapists? routine of work, benefiting patients of all ages and with different problems. The manufacturing of a PEMF device by national companies is suggested in order to reduce costs and to facilitate the access to this physical agent.
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Humans , Male , Female , Magnetic Field Therapy , Physical Therapy Modalities , TherapeuticsABSTRACT
Objective To develop medical equipment suited for medical care.Methods The secondary auxiliary wings were added inside the original intravenous infusion dressing clips on the left and right,and then a new stereo magnetic infusion dressing came into being with the medical 3M sticking membrane and glutinous magnetic woundplast.Results The Stereo Magnetic Intravenous Infusion Dressing was gifted with the functions of observing,supporting,and fixing the sting area.The model successfully passed the animal experiments.Conclusion The new stereo magnetic infusion dressing,easy to use,can satisfy the requirements of medical care.