ABSTRACT
Objective To analyze the distribution of pathogens isolated from medistream urine specimens of patients with urinary infection and their antibacterial susceptibility ,so as to provide references for rational use of antibacterial agents .Methods A total of 853 medistream urine specimens collected from January to December 2014 in this hospital were cultured ,bacterial identification and antimicrobial susceptibility testing were carried in the isolates .Results Pathogens were isolated from 245 medistream urine specimens ,and the positive rate was 28 .7% .A total of 269 strains were isolated and most were gram‐negative bacteria(accounted for 60 .2% ) ,followed with gram‐positive bacteria(accounted for 33 .8 % ) and fungi(accounted for 5 .9% ) .A total of 48 strains of extended‐spectrumβ‐lactamases(ESBLs)producing Escherichia coli and 3 strains of ESBLs producing Klebsiella pneumoniae were i‐solated .The detection rate of methicillin resistant Staphylococcus epidermidis (MRSE) and methicillin resistant Staphylococcus au‐reus(MRSA) was 17 .6% and 35 .8% ,respectively .Conclusion Clinical physicians should scientifically and rationally select anti‐bacterial drugs according to drug‐sensitivity results and avoid blindly empirical use of antibacterial agents ,in order to reducing and controlling the emergence and prevalence of ESBLs producing strains and other drug‐resistant bacteria .