Clinical relevance of cagA and vacA and association with mucosal findings in Helicobacter pylori-infected individuals from Chennai, South India

Helicobacter pylori is associated with a spectrum of severe gastrointestinal conditions. In this study, an attempt was made to correlate endoscopic mucosal patterns with H. pylori infection and examine the pathogenic potential of the strains. Among the 147 dyspeptic individuals studied, 42.2% were H. pylori infected. Association of H. pylori with type 3 and 4 mucosal patterns (P = 0.001) and intestinal metaplasia (P = 0.012) was seen. vacA was associated with histological (P = 0.014) and endoscopy findings (P = 0.009). Association of mucosal patterns with H. pylori infection could be useful for clinicians to decide on the need for eradication therapy.

A REPORT OF 97 CASES OF GASTRIC MUCOSAL LESIONS DIFFERENTIATED BY AH PAINT / 西安交通大学学报(医学版)

93 gastric cancer cases and 4 gastric dysplasiaspecimen are fixed and then washed off the mucuswith water, and dyed with Alcianblue (A) andHeamatoxylin (H) respectively. The result is thatsome microscopic structures of the mucosal surfaceshow the differential patterns. Early carcinoma(especially the microcarcinoma), dysplasia and in-testinaligation are different in color and mod-el. Gastric carcinoma shows unpaint or weak paint,and pattern's spare, break or zodent. The incidencerate of microcarcinoma is 70. 6%.