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【Objective】 To explore the impacts of groove negative pressure drainage on the short-term prognosis of patients with transperineal anastomotic urethroplasty. 【Methods】 A retrospective case-control study was conducted to analyze the clinical data of 78 patients who underwent transperineal anastomotic urethroplasty during May 2021 and Apr.2022, including 42 patients in the groove negative pressure drainage group (experimental group) and 38 in the rubber strip drainage group (control group). The postoperative drainage volume, rate of scrotal edema, rate of infection, visual analog scale (VAS) score, and maximum urine flow rate were compared between the two groups. 【Results】 Compared with the control group, the experimental group had a longer length of incision [ (12.9±1.6)cm vs. (12.1±1.5)cm, P=0.041] and larger drainage volume 3 days after surgery [(66.1±51.9)mL vs. (36.0±16.9)mL, P=0.001] , but lower rate of scrotal edema (21.4% vs.47.2%, P=0.016) and lower VAS score (3.2±1.0 vs.3.9±1.1, P=0.008). There were no significant differences in the infection rate 7 days after surgery and the maximum urine flow rate 1 month after surgery (P>0.05). 【Conclusion】 Groove negative pressure drainage can be used to drain the effusion of perineum tissue adequately and decrease wound-specific complications, which is beneficial to the rapid recovery after transperineal anastomotic urethroplasty.
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Objective:To compare the use of continuous constant negative pressure drainage and intermittent suction mode drainage in abdominal wall angioplasty to minimize the impact of complications.Methods:From May 2017 to August 2019, the Department of Medical Cosmetology and Plastic Surgery, Wuhan Third Hospital treated 76 female patients after expanded flap repair, aged 27-35 years, with an average age of 30.5±14.2 years, and 58 female patients after abdominal wall plasty, aged 38-55 years, with an average age of 47.8±7.8 years. They were divided into intermittent negative pressure drainage group and continuous negative pressure drainage group. The negative pressure values in different intervals were set according to the type of operation. The drainage volume, drainage time, incidence of hematoma, subcutaneous effusion, flap necrosis rate, primary wound healing rate and drainage related bleeding were recorded and compared between the two groups.Results:After expanded flap repair in 38 cases, flap necrosis occurred in 1 case and hematoma in 3 cases; After abdominal wall plasty in 29 cases, flap necrosis occurred in 0 cases and hematoma in 1 case. The primary healing of incision was higher ( P<0.05), the drainage volume was larger, but the drainage time was shorter ( P<0.05), and no bleeding related to drainage was observed. The effect of monitoring drainage was positively correlated with the effect of operation. Conclusions:Continuous and constant negative pressure drainage is related to the prognosis of patients undergoing expansion flap repair and abdominal wall plasty. It is helpful to improve the effect of plastic surgery and the quality of nursing work. It is an effective method for nursing management after plastic surgery.
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@#AIM:To report our precaution practices for ocular surgeries under local anesthesia during COVID-19 outbreak and evaluate the respiration situation among the patients with medical face masks under ocular surgeries.<p>METHODS:Sixty Chinese patients needed eye surgery treatment were recruited and given medical face masks as one of the COVID-19 precaution practices during eye surgery with local anesthesia. Oxygen supplementation and negative pressure drainage were applied to relieve the potential respiratory discomfort, and the respiratory comfort score was evaluated.<p>RESULTS:Patients with medical face masks experienced mild to moderate respiratory discomfort with an overall mean score of 2.34±0.73. Supplementation of oxygen together with negative pressure drainage relieved this discomfort(overall mean score of 0.15±0.75; <i>P</i><0.001). There is no gender and operation time difference on respiratory discomfort or discomfort relieve. Failure in negative pressure drainage led to severe respiratory discomfort.<p>CONCLUSION:Negative pressure drainage could maintain the respiratory circulation in patients with medical face mask under eye surgery with local anesthesia. Application of medical face masks in patients under surgeries is recommended to protect the medical practitioners during the operations within COVID-19 outbreak.
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BACKGROUND: Platelet-rich plasma and negative pressure drainage therapy have been widely used and achieved good clinical outcomes in the treatment of various chronic wounds. However, there is no randomized controlled trial regarding their combined effect on chronic refractory wounds. OBJECTIVE: To systematically evaluate the efficacy of platelet-rich plasma with negative pressure therapy on chronic refractory wounds. METHODS: Databases of CNKI, VIP, WanFang, SinoMed, Web of Science, PubMed, and EMbase were searched for the randomized controlled trials regarding the efficacy of platelet-rich plasma combined with negative pressure therapy on chronic refractory wounds. Included studies were evaluated using the Cochrane system evaluation method. Meta-analysis was performed using RevMan 5.3 software. The primary outcomes included wound healing rate, time for wound healing, length of hospital stay, pain score and positive rate of bacteria. RESULTS AND CONCLUSION: A total of 11 randomized controlled trials were included, including 743 patients with chronic wounds. The observation group was treated with platelet-rich plasma combined with negative pressure drainage. The control group was treated with conventional dressing or simple negative pressure drainage. The Meta-analysis results showed that compared with the control group, there was significantly increased wound healing rate [relative risk (RR)=2.19, 95% confidence interval (CI) (1.82, 2.62), P < 0.000 01], significantly shortened time for wound healing [mean standard difference=-0.81, 95%CI (-1.00,-0.62), P < 0.000 01], significantly shortened length of hospital stay [mean difference=-7.11, 95%CI (-8.12,-6.11), P < 0.000 01], and significantly lowered positive rate of bacteria [RR=0.35, 95%CI (0.22, 0.54), P < 0.000 01] in the observation group. There was no significant difference between the two groups in the pain score [SMD=-5.97, 95%CI (-14.33, 2.40), P=0.16]. To conclude, platelet-rich plasma combined with negative pressure drainage can promote the healing of chronic refractory wounds and reduce the incidence of infection.
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Objective@#To explore the clinical application value of closed negative pressure drainage technique in the treatment of external foot injury.@*Methods@#Sixty-eight patients with hand and foot trauma admitted to the Enze Hospital of Taizhou Enze Medical Center (Group) from November 2017 to November 2018 were randomly divided into the control group and the observation group according to the digital table, with 34 cases in each group.The control group underwent routine skin grafting.The observation group underwent closed vacuum drainage.The therapeutic effects, wound healing rate and clinical observation indicators were compared between the two groups.@*Results@#The total effective rate (88.24%) and the overall wound healing rate (100.00%) in the observation group were significantly higher than those in the control group (64.71%, 79.41%) (χ2=5.231, 7.803, P=0.022, 0.005). The operation time[(5.92±1.02)h], wound healing time[(16.65±8.01)d] and hospitalization time[(31.42±13.05)d] in the observation group were significantly shorter than those in the control group[(8.33±1.65)h, (23.51±12.12)d, (46.35±18.89)d](t=7.244, 2.753, 3.792, P=0.001, 0.008, 0.001).@*Conclusion@#Application of closed negative pressure drainage technique in hand and foot trauma surgery can effectively improve clinical efficacy, accelerate the healing speed of wounds, and reduce the operation time and hospitalization time of patients.It is worthy of promotion.
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BACKGROUND@#Mediastinal infection is a serious infection of mediastinal connective tissue, with more complications and higher mortality. Application of broad-spectrum antibiotics and nutritional support, early sufficient drainage is the key to successful treatment. In the mode of drainage, this paper discusses the application of continuous negative pressure drainage technique to treat acute anterior mediastinal infection of severe mouth pharynx source, and the good results are summarized and shared.@*METHODS@#In January to December in 2017, a total of 17 cases treated acute mediastinal infection is derived from the throat, has formed a mediastinal abscess, surgery adopts retrosternal counterpart negative pressure drainage way, namely the sternum nest and free sternum xiphoid process under the incision on the first mediastinal clearance, make breakthrough and placed drainage device, suture closed wound, continuous negative pressure drainage, negative pressure using 3 cm-5 cm water column.@*RESULTS@#Among the 17 patients, 14 patients were relieved by continuous negative pressure drainage, and then the drainage tube was removed. In 2 cases, the infection broke into the right thoracic cavity, and the closed drainage caused the negative pressure to disappear, and the negative pressure drainage was replaced by the conventional drainage, and the drainage tube was removed after the drainage tube was clear. One patient had formed a mediastinal abscess incision drainage time later, complicated with septic shock and sepsis, resulting in the death of multiple organ failure.@*CONCLUSIONS@#The traditional treatment of severe acute mediastinal infection is sternal incision and drainage. Continuous negative pressure drainage adequate drainage of mediastinal can relieve patients' pain, effusion, and avoid the dressing out repeatedly. It is an effective method. However, there are limitations in this method, which need to be further optimized.
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Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , Drainage , Methods , Mediastinal Diseases , Diagnostic Imaging , General Surgery , Mediastinum , Diagnostic Imaging , General Surgery , Pharyngeal Diseases , Diagnostic ImagingABSTRACT
Objective To observe the clinical effect of continuous vacuum sealing drainage (VSD) in trea-ting diabetic foot and its influence on the expression of serum insulin-like growth factor(IGF1) and nitric ox-ide(NO) .Methods Sixty-eight cases of diabetic foot in this hospital from June 2014 to December 2015 served as the research subjects and randomly divided into the control group and observation group .The control group took the common wound dressing treatment ,while the observation group adopted the VSD treatment ;the clin-ical efficacies after three courses of treatment were compared between the two groups .The treatment time , number of dressing change and wound healing time in the two groups were performed the statistics .The data after completely statistics were performed the contrastive analysis ;glycosylated hemoglobin (HbA1c) ,IGF1 and NO expression levels before and after treatment were compared between the two groups .The correlation between clinical effect with the levels of IGF1 ,NO and HbA1c was analyzed .Results The clinical cure rate of the observation group was 52 .94％ ,the total effective rate was 94 .12％ ,the clinical cure rate of the control group was 35 .29％ ,the total effective rate was 67 .65％ ,and the results of curative effect evaluation in the ob-servation group was better than that of the control group ,the difference was statistically significant ( P<0 .05) .The observation group was significantly better than the control group in the treatment time ,dressing change frequency and wound healing time ,the difference was statistically significant (P<0 .05) .After three courses of treatment ,the average expression level of IGF1 and NO in the observation group were higher than those in the control group ,the difference was statistically significant (P<0 .05) .There was a negative correla-tion between the curative effect and the level of serum IGF1 and NO (r= -0 .997 ,-0 .923 ,P< 0 .05) ,and there was a positive correlation between the curative effect with the HbA 1c level(r=0 .816 ,P<0 .05) .Conclu-sion VSD has an ideal effect in the treatment of diabetic feet ,can effectively shorten the treatment time ,and has the recovery of serum IGF1 and NO expression level .
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The common negative pressure drainage bottle used in the vacuum sealing drainage (VSD) cannot quantitative and automatically cut off. Excessive drainage damages the negative pressure source, causes drainage interruption, so once drainage was continuously performed, medical staff need to closely observe drainage bottle calibration. It was also important to known whether there was a large amount of fresh blood sucked out during continuous drainage because it could lose too much blood. To solve these two problems, we designed a kind of negative pressure drainage device, which volume was constant, with the function of automatic cutting off continuous drainage. It can not only prevent drainage fluid flowing back to the negative pressure source and cause drainage interruption, but also prevent massive blood loss from continued drainage after the hemorrhage. We could benefit from this device, which possess many advantages, such as simple structure, security and reliability. It is worthy promoting in the clinical work.
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Objective To investigate the efficacy of flexor muscle disconnection combined with myocutaneous flap in the treatment of pressure ulcer in patients of ankylosing posture.Methods A retrospective case series study was conducted to analyze 15 patients with pressure ulcer at different body parts due to ankylosing posture after paraplegia admitted to the First Affiliated Hospital of Jinan University from January 2012 to July 2017.There were 10 males and five females,aged 40-78 years,with an average age of 68 years.The pressure ulcer ranged from 3 cm× 3 cm to 15 cm × 11 cm.The pressure ulcers were distributed at sacrococcygeal region in eight patients,macro-rotator in four,and ischial nodules in three.According to the size and position of pressure ulcer,different musculocutaneous flaps were selected,and high selective decompression of hip flexion and knee flexion was performed to ensure the tension free suture of the wound.After the operation,the negative pressure closed drainage (VSD) was given to maintain a proper posture for wound healing.The stitches were removed after the wound healed.The wound healing,pressure ulcer recurrence,flap texture,flap color,and donor site were observed,and patient satisfaction were also surveyed.Results All patients were followed up for 12-36 months,average 24 months.The pressure ulcer was healed in 12 patients after the first repair operation.In two nonunion cases,the unrelieved knee flexion and knee muscles led to high muscular tension and stiff joint,causing strong resistance during limb movement and strong flexor reflex.Two patients were healed after twice operation.In one patient,the incision was torn by the excessive flexion tension due to improper body position caused by the passive movement of the limb after operation,and the wound was healed after twice operation.All muscle flaps covered the wound and survived well,and the wounds were completely closed and healed with good shape,texture as well as elastic recovery.After the suture was removed18 days after surgery,the patients were discharged satisfactorily.The patients received conventional pressure ulcer care,and no new pressure ulcer was reported during the follow-up.The flap donor site was healed well after autologous skin repair.Conclusion For pressure ulcer in patients of ankylosing posture,flexor muscle disconnection combined with myocutaneous flap has notable effects in reducing tension and can accelerate wound healing and improve healing rate.
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Objective To investigate the clinical effect of adjustable negative pressure drainage technique in the treatment of subcutaneous acute cellulitis.Methods Thirty patients with acute cellulitis were treated with adjustable pressure drainage technique after incision and drainage of subcutaneous infection.Results 22 patients with subcutaneous infectious wounds took the secondary suture after carrying out one-time regulated negative pressure therapy,and 8 patients with subcutaneous infectious wounds took the secondary suture after carrying out twice negative pressure therapies.The average time of negative pressure treatment was (7.3 ± 1.0) days.Thirty patients had subcutaneous infection wounds healed well and no recurrence was observed at 3 months follow-up.ConclusionThe repairment of negative pressure therapy adopted to treat the subcutaneous acute cellulitis can rapidly reduce the local and general symptoms of the patient,and apparently reduce the dressing change times.With simple operation and reliable curative effect the relapse rate of subcutaneous infectious wound can be enormously reduced.
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Objective To investigate the clinical value of self-made dressing negative pressure drainage technique in the treatment of the four limbs soft tissue trauma.Methods A total of 60 patients with the four limbs soft tissue trauma in our hospital from December 2013 to December 2014 were randomly divided into the observation group and control group.The observation group with 30 cases were treated with the self-made negative pressure drainage technique,and the control group with 30 cases received the conventional treatment.The pain score,wound healing rate,complication rate between two groups were compared.Results The pain score of the observation group was(1.17±0.22),which was lower than(3.17±0.49) of control group,the difference was statistically significant(P<0.05).The wound healing rate of observation group(73.33%) was higher than that of the control group(40%),the difference was statistically significant(P<0.05).The complication rate of observation group(3.33%) was lower than that of control group(23.33%),the difference was statistically significant(P<0.05).Conclusion The self-made dressing negative pressure drainage technique applied to the patients of four limbs soft tissue trauma can reduce the pain,shorten the healing time,and reduce the incidence of complications.
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Objective To discuss continuous negative pressure suction and different negative pressure monitoring after the external ear reconstruction operation stage Ⅱ,aiming to improve the security of the plastic surgery.Methods A lot of 87 microtia patients aged 6-15 years were randomly selected as control group from Feb.2010 to Mar.2012,and other 87 cases of microtia were also randomed as experimental group from Apr.2012 to Apr.2014.The experimental group adopted the continuous negative pressure suction and the pressure value was set as 3.99-5.32 kPa (30-40 mmHg);the control group adopted the method of traditional intermittent negative pressure drainage and the suction pressure was set as 3.99-7.98 kPa (30 60 mmHg).After the operation,the two groups were observed and compared under continuous negative pressure suction.The capacity,color changes,length of time,and pressure value of the drain were monitored and observed,finding out their correlation with the operation effectiveness.Results For the experimental group,the incidence of subcutaneous hydrops and skin flap necrosis was lower (P＜0.05),and the primary healing rate was higher than the control group (P＜0.01).The capacity of drain was relevant to the type of the plastic surgery,different from 5 to 20 ml;the color changed gradually from blood color to faint yellow;the extubation time was generally from 7 to 10 days.The optimal pressure value was 3.99-5.32 kPa (30-40 mmHg);there was proportional relation between the effectiveness of monitoring drainage and the operation effectiveness.Conclusions Continuous negative pressure suction monitoring after operation contributes to improve the plastic surgery effectiveness,and the patients are satisfied with the result.
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Objective To investigate the clinical effect of adjustable negative pressure drainage technique in the treatment of subcutaneous acute cellulitis.Methods Thirty patients with acute cellulitis were treated with adjustable pressure drainage technique after incision and drainage of subcutaneous infection.Results 22 patients with subcutaneous infectious wounds took the secondary suture after carrying out one-time regulated negative pressure therapy,and 8 patients with subcutaneous infectious wounds took the secondary suture after carrying out twice negative pressure therapies.The average time of negative pressure treatment was (7.3 ± 1.0) days.Thirty patients had subcutaneous infection wounds healed well and no recurrence was observed at 3 months follow-up.ConclusionThe repairment of negative pressure therapy adopted to treat the subcutaneous acute cellulitis can rapidly reduce the local and general symptoms of the patient,and apparently reduce the dressing change times.With simple operation and reliable curative effect the relapse rate of subcutaneous infectious wound can be enormously reduced.
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Objective To explore the clinical effect of patients of oral and maxillofacial space infection treated with improved closed negative pressure drainage combined with hyperbaric oxygen, and the possibility of using this method to decrease the hospital expenses. Methods 156 patients with oral and maxillofacial space infection were divided into control group, closed negative pressure drainage group and improved closed negative pressure drainage combined with hyperbaric oxygen group by random number table. 52 patients in each group. The granulation tissue growth time, the healing of wound, clinical effect of the 8thday, hospitalization days, wound healing time, antibiotic cost, average cost in hospital were recorded after treatment. Results The average wound healing time of patients in improved closed negative pressure drainage combined with hyperbaric oxygen group was(6.06 ± 0.23)days, while the granulation tissue growth time was(16.13 ± 2.89)days, both of them were much shorter than the control group[(15.46 ± 4.68)days and(28.60 ± 3.50)days respectively],as well as the closed negative pressure drainage group [(7.43 ± 0.75) days and (22.67 ± 4.34) days respectively], and the differences were statistically significant which the F values equaled to 6.213 and 8.451, P values all less than 0.05. The total healing rate of patients in closed negative pressure drainage group and improved closed negative pressure drainage combined with hyperbaric oxygen group were both 100.00%(52/52), the difference was statistically significant compared with control group (χ2=6.89, P<0.05). The average hospitalization days of the patients in the closed negative pressure drainage group and improved closed negative pressure drainage combined with hyperbaric oxygen group were (8.20 ± 1.49) days and (7.45 ± 0.42)days, the antibiotic cost were(5 068.34 ± 1 074.68)RMB and (5 001.00 ± 456.00) RMB, the average total cost were (9 457.43 ± 647.23)RMB and (9 249.00 ± 367.00)RMB, all these indexes were much lower that which in control group[(18.40 ± 5.89)days,(21 000.43 ± 2 036.48) RMB and (31 000.66 ± 2 711.36) RMB], and the differences were statistically significant, F values equaled to 15.221, 29.434 and 81.220 each, P values were all less than 0.01. Conclusions Improved closed negative pressure drainage combined with hyperbaric oxygen method could improve the clinical effect of patients with oral and maxillofacial space infection, speed up the granulation tissue, shorten the in-hospital time as well as reduce the medical cost.
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Objective To study the application of negative pressure drainage on nasal septum reconstructomy by endoscopy.Methods Totally 80 patientswith nasal septum deviation in our hospital from May 2014 to March 2015 were randomly divided into the observation group and the control group.All patients were given nasal septum reconstructomy by endoscopy,and patients of the observation group were given negative pressure drainage after surgery while the patients in control group were given traditional nasal cavity filling postoperatively.Observed the subjective symptoms,degree of disease and complications of patients 12 hours and 24 hours after surgery.And the clinical curative effect of the two groups were compared and analyzed 1 week after the surgery.Results The subjective symptoms of the observation group was obvi-ously better than the control group 24 hours after the surgery with statistically significant difference (P <0.05).And the degree of disease in observation group had significantly improved,and the nasal mucosa edema ratio of level 0 was 40%,which was significantly higher than 10% in the control group (P <0.05).The total effective rate was 97.50% in the observation group 1 week after surgery and it was 80% in the control group,and there were significant difference between the two groups (P <0.05).The incidence of complications in the observation group was 2.50%,which was significantly less than 20% in the control group (P <0.05).Conclusion The application of negative pres-sure drainage on nasal septum reconstructomy by endoscopy could effectively relieve the pain of patients and reduce complications,and its prognosis effect is better.
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Objective To summarize the clinical effect and experience of vacuum sealing drainage ( VSD) technology combined with sural neurovascular flap to repair chronic and infection soft tissue defects in the foot and ankle?Methods From 2010 to 2015, the clinical effect of 58 cases patients who were treated negative pressure drainage combined with sural nerve nutrient vessel flap for repairing foot and ankle chronically infected wounds in Zhongnan Hospital of Wuhan University were retrospective analyzed?All cases were treated by debridement,negative pressure suction 1, 2 times, cleaning the wound, Wound secretions were negative after culture,then cut and take the nutrient vessels of the nutrient vessels to repair the wound?Results All flaps survived completely in 58 cases,54 cases inⅠstage healing,postoperative 4 cases were suffered with distal skin flap necrosis,and healed after dressing?The outline and function were satisfactory during 1 to 3 years follow?up?Conclusion The effect of negative pressure drainage combined with sural nerve nutrient vessel flap for repairing chronic wound of foot and ankle is exact, skin flap transposition of the wound should be thoroughly debridement,edge scar tissue should be appropriate resection.
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This paper reported 13 cases of delayed traumatic chest wall abscess from January 2012 to January 2015.All the patients were associated with type 2 diabetes.After local puncture for confirmative diagnosis, a chest wall abscess dissection was carried out as soon as possible.At each site of upper and lower pole, an indwelling drainage tube was placed for irrigation and negative pressure suction.Sensitive antibiotics were selected based on susceptibility test results.The drainage tubes were removed 7-14 days after surgery.There were 8 cases of primary healing of incision and 5 cases of secondary healing of incision.All the patients were cured.Follow-ups for 6-36 months (average, 17 months) showed no recurrence.
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Objective To evaluate the efficacy and safety of presetting negative pressure drainage for anastomotic leakage after esophageal cancer surgery. Methods The clinical data of 68 patients with intrathoracic anastomotic leakage following surgery of esophageal and cardial carcinoma from January 2008 and January 2014 were retrospectively analyzed The patients were divided into 3 groups, including presetting negative pressure drainage group (Group A), endoscopy drainage placement group (Group B) and traditional treatment group (Group C). Results A total of 1 251 patients underwent intrathoracic anastomosis were analyzed and anastomotic leakage occurred in 68 cases (5. 4%), with 14(20. 6%) died after operation. The mortality rates of Group A and Group B were significantly lower than that in Group C (14. 3%, 0 vs 39. 1%, P<0. 05). The repeated drainage times in Group A and Group B were signficantly less than that in Group C (P<0. 05). Compared with Group B and Group C, Group A had the advantage of shorter manipulation time (P<0. 05). Drainage lavaging time, recovery time and retaining time of gastric tube in Group A and Group B were significantly shorter than those in Group C(P<0. 05). Patients in Group A and Group C had significantly less discomfort in nasopharynx and significantly lower obstruction incidence compared with those in Group B (P<0. 05). Except for death, all patients with anastomotic leakage had normal diet and safe discharge after prompt treatment. Conclusion Presetting negative pressure drainage after esophageal cancer surgery has a better effect for anastomotic leakage by reducing recovery time, lowering mortality rate and alleviating the suffering of patients.
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Objective To evaluate the clinical efficacy of continuous irrigation with recombinant human acid fibroblast growth factor (rh-aFGF) combined with negative-pressure drainage in the treatment of refractory skin ulcer.Methods A clinical trial was performed from January 2010 to December 2012.Sixty patients with refractory skin ulcer were randomly and equally classified into three groups:group A receiving continuous irrigation with rhaFGF combined with negative-pressure drainage,group B receiving irrigation of raw surfaces with rh-aFGF followed by bandaging after debridement,group C receiving covering of raw surfaces with Vaseline gauze and absorbent gauze followed by bandaging after debridement.Dressings were changed once daily in every group.The treatment lasted 21 days.The efficacy of these regimens was evaluated on day 7,14 and 21.Results At the above time points for observation,both the granulation and epithelium tissues of ulcers grew well in group A,with a decrease in the volume of wounds and area of exposed deep tissues.There was a significant increase in the cure rate and reduction rate of wound volume in group A compared with the other two groups (all P ＜ 0.01).Conclusion Refractory dermal ulcer can be treated with continuous irrigation with rh-aFGF combined with negative-pressure drainage.
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Objective To explore the curative effect of modified closed negative pressure drainage on abnormal abdominal incision. Methods Sity-three patients with abnormal healing of abdominal incision in our hospital from January 2012 to June 2013 were selected as the observation group. Another 50 patients from January to December 2011 were assigned to the control group. The former was treated after debridement with human recombinant surface growth factor and modified closed negative pressure drainage,while the latter after debridement with anti-infection and dressings of ethacridine or gentamicinsolution as well as with infrared therapy. The two groups were compared in terms of the frequency,time and cost of changed dressings,and the healing time of the incisions.Results There was insignificant difference in the cost of changed dressings between the two groups(P>0.05). However,the differences were statistically significant in terms of the frequency and time of changed dressings and the healing time of the incisions(P<0.05). The observation group was significantly superior to the control group.Conclusions Modified closed negative pressure drainage is effective in accelerating the healing in abnormal abdominal incisions,reducing the frequency and the time of changed dressings,and easing the economic burdens of the patients,which is suggested to be popularized and applicable in the pimary hospitals.