Progress on the Muscle Function Evaluation and Its Forensic Application / 法医学杂志

Accurate evaluation of muscle function helps to understand the recovery of muscle, bone, nervous system diseases or injuries, especially for muscle dysfunction caused by peripheral nerve injury.Therefore, the methods of muscle function evaluation have been the focus of researchers, with new methods having been constantly proposed.Muscle strength testing is an important part of muscle function evaluation.Besides hand muscle strength assessment, currently used muscle function assessments include simple instrumental test, isokinetic muscle test, electrophysiological test, etc.In addition, the application of needle electromyography, motor unit number estimation, motion unit index in muscle function evaluation has also been reported for several times.This paper reviews the research progress and practical application of these methods.

Regulation action and nerve electrophysiology mechanism of acupuncture on arousal state in patients of primary insomnia / 中国针灸

<p><b>OBJECTIVE</b>To compare the difference between acupuncture and estazolam on arousal state in patients of primary insomnia, and to explore its nerve electrophysiology mechanism.</p><p><b>METHODS</b>Sixty-four patients of primary insomnia were randomized into an acupuncture group (32 cases) and a medication group (32 cases). After 3 patients were excluded, 31 cases in the acupuncture group and 30 cases in the medication group were included. Patients in the acupuncture group were treated with acupuncture at Sishencong (EX-HN 1), Anmian (Extra), Shenmen (HT 7), Sanyinjiao (SP 6), Zhaohai (KI 6), Shenmai (BL 62) as main acupoints, combined with supporting acupoints, once a day, five times per week, continuously for 4 weeks. Patients in the medication group were treated with oral administration of estazolam, once a day, continuously for 4 weeks. The Pittsburgh sleep quality index (PSQI) and mean sleep latency (MSL) of multiple sleep latency test (MSLT) were compared before and after treatment in the two groups; the polysomnography (PSG) was applied to monitor the indices regarding sleep structure.</p><p><b>RESULTS</b>Compared before treatment, PSQI score was reduced after treatment in the two groups (both<0.01), which was more significant in the acupuncture group (<0.05). Compared before treatment, sleep onset latency (SOL), number of awakenings (NWAK) and wake after sleep onset (WASO) were reduced, while total sleep time (TST) and sleep efficiency (SE) were significantly increased in the two groups after treatment (all<0.01). Compared before treatment, the percentage of non-rapid eye movement period 1/2/3 (N1, N2, N3) and the percentage of rapid eye movement period (REM) to TST were not significantly changed after treatment in the medication group (all>0.05). Compared before treatment, the percentage of N1, N2 to TST was reduced, while the percentage of N3 and REM to TST was increased after treatment in the acupuncture group (<0.01). The SOL, NWAK, WASO, TST, SE were not statistically changed after treatment in each group (all>0.05). Compared with the medication group, the percentage of N1 and N2 was reduced while that of N3 and REM was increased after treatment in the acupuncture group (all<0.01). After treatment, MSL of MSLT were obviously decreased in the two groups (both<0.01), which were more significant in the acupuncture group (<0.05).</p><p><b>CONCLUSIONS</b>Acupuncture can more effectively improve sleep quality of primary insomnia than estazolam, and is more beneficial for regulation of hyperarousal state.</p>

Critical Antigenic Structure in Inducing Immune Damage of Peripheral Nerve Following Campylobacter Jejuni Infection / 实用儿科临床杂志

0.05).3.Thirty-three point three percent of animals from parental strain group were found fibrillations potentials and the po-sitive sharp waves in gastrocnemius electromyogram,no obvious abnormal waves were found in animals from both waaF mutant and control group.Conclusions The ganglioside-like epitope in LOS of CJ is critical antigen in inducing GM1-IgG antibody and in inducing conduction block of peripheral nerve,therefore,provide a support for the molecular mimicry theory as a pathogenesis in the axonal GBS following CJ infection.

Electrophysiological studies in patients with acute tetrodotoxin poisoning / 临床神经病学杂志

Objective To evaluate the electrophysiological change in patients with acute tetrodotoxin(TTX) poisoning.Methods The electromyogram, motor nerve conduction velocity(MCV), sensory nerve conduction velocity(SCV),F wave,H reflex and somatosensory evoked potentials(SEP) were randomly detected in 58 patients with acute TTX poisoning.Results 22 patients with TTX(37.9%) detected by the electromyogram showed mainly polyphase irregular waves;MCV and SCV were weakened; SCV was even more remarkable,the latency of distant MCV action potentials was prolonged obviously, the abnormality rate of nerve conduction velocity was much higher than that of fibrillation,the detectable rats of positive wave was high,the low abnormality rate of F wave and H reflex suggested that the ill TTX poisoning involved the nerve roots;the abnormality rate of SEP was 56.9%.Conclusion TTX poisoning can company with the damage of central nerves, the measure of electroneurophysiology can be used to observe the extent,course and range of nerve system damage in patients with acute TTX poisoning, and it is one of the early detection means of this disease.