ABSTRACT
The technology of network analysis,based on a variety of disciplines theory,is the core technology in the research of network pharmacology,through which we can mine specified information from molecular networks from multi-angle and multi-level. It has been used to investigate and obtain valuable information about the ingredients/drugs with specific pharmacological effects ,the key nodes,modules and motifs with specific biological function,and physiological mechanism of drug action,pathogenesis of dis?ease,or biomarker of disease,especially for the complex disease represented by Alzheimer′s disease(AD). In this paper,the general techniques of network analysis in network pharmacology study are reviewed.
ABSTRACT
The technology of network analysis, based on a variety of disciplines theory, is the core technology in the research of network pharmacology, through which we can mine specified information from molecular networks from multi-angle and multi-level. It has been used to investigate and obtain valuable information about the ingredients/drugs with specific pharmacological effects, the key nodes, modules and motifs with specific biological function, and physiological mechanism of drug action, pathogenesis of disease, or biomarker of disease, especially for the complex disease represented by Alzheimer’s disease (AD). In this paper, the general techniques of network analysis in network pharmacology study are reviewed.