1.
Chinese Journal of Rehabilitation Theory and Practice
;
(12): 538-540, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-965271
ABSTRACT
@#Neuron axonal signals play an important role in myelination of central nervous system. Myelination depends on a balance between the positive and negative neuron axonal signals. The positive signals, such as neuregulins (NRG), neuron cell adhesion molecule (NCAM), electrical activity and neurotrophins, have a function of promoting the proliferation and the myelination thickness of ensheathing glial cells, while the negative factors like the L1 protein, poly-sialic acid-neuron cell adhesion molecule (PSA-NCAM), will lead a marked decrease in myelination. Here,we mainly present some well-researched neuron axonal factors and their mechanism.