1.
Acta Pharmaceutica Sinica
;
(12): 554-565, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-820854
ABSTRACT
Hepatitis B virus (HBV) capsid protein plays an important role in the life cycle, thus becoming an ideal target for drug design. Capsid protein inhibitors can exert a synergistic antiviral effect with nucleoside drugs by inhibiting the replication of HBV. This paper reviews the research progress of capsid protein inhibitors with different structural types from the perspective of medicinal chemistry.