ABSTRACT
El manejo del dolor articular ofrece para la población afectada novedosos suplementos nutricionales que incluyen el colágeno, y cuya extracción es desde variadas fuentes de origen animal, no así de vegetales. Esta revisión tiene como objetivo aclarar qué es el colágeno, su constitución estructural molecular, el rol que cumple en nues-tro organismo y revisar las indicaciones propuestas por la literatura, tanto para la profilaxis como el tratamiento de cuadros reumatológicos de alta prevalencia o impacto funcional, como son Artrosis, Artritis Reumatoidea y Osteoporosis.
Novel nutritional supplements for the management of joint pain have been made available to the population, including collagen, which can not be extracted from plant products, but from a variety of animal sources. This review aims to clarify what it is collagen, the molecular structures that constitute it, the determined role they play in our body and review the indications that the literature proposes both in prophylaxis and treatment, for high prevalence rheumatologic or functional impact, such as osteoarthritis, rheumatoid arthritis and osteoporosis.
Subject(s)
Humans , Rheumatic Diseases/therapy , Collagen/therapeutic use , Osteoarthritis/therapy , Osteoporosis/therapy , Arthritis, Rheumatoid/therapy , Extracellular MatrixABSTRACT
Nanchi (Byrsonima crassifolia), arrayan (Psidium sartorianum) and ayale (Crescentia alata) are wild and under-utilized plants from Mexico; their fruits have been used as food and as Mexican traditional remedies against human bacterial infections (e.g. bacillary dysentery). However, scientific reports which support such uses or promote their consumption are scarce. In this work, the antibacterial activities of fruit extracts (i.e. hexanic, HE; chloroformic, CE; and methanolic, ME) were determined by the micro-dilution assay, establishing the Minimum Inhibitory Concentration (MIC) and Minimum Bactericide Concentration (MBC) against 21 human pathogenic bacteria. The HE of arrayan and ayale showed the highest activity against enterobacteria (E. coli, Salmonella spp. and Shigella spp.) (MIC 0.25-2 mg/mL; MBC 0.5-16 mg/mL). The arrayan ME was the most active against the Gram-positive bacteria, showing Staphylococcus aureus the highest sensitivity (MIC 2 mg/mL; MBC 2-4 mg/mL). The presented results support the traditional uses of these plant materials for treating bacterial infectious diseases.
Nanchi (Byrsonima crassifolia), arrayán (Psidium sartorianum) y ayale (Crescentia alata) son plantas silvestres subutilizadas de México; sus frutos son comestibles y usados como medicamentos tradicionales contra infecciones bacterianas humanas (e.g. disentería bacilar). Sin embargo, los reportes científicos que avalen los usos y promuevan su consumo son escasos. En este trabajo se determinó, ensayo de micro-dilución en caldo, la Concentración Mínima Inhibitoria (CMI) y Concentración Mínima Bactericida (CMB), de los extractos de frutos (hexánico, EH; clorofórmico, EC; y metanólico, EM) contra 21 bacterias patógenas humanas. Los EH de arrayán y ayale mostraron la mayor actividad (CMI 0.25-2 mg/mL; CMB 0.5-16 mg/mL) contra enterobacterias (Escherichia coli, Salmonella spp. y Shigella spp.). El EM de arrayán fue el más activo contra bacterias Gram positivas, presentando Staphylococcus aureus la mayor sensibilidad (CMI 2 mg/mL; CMB 2-4 mg/mL). Estos resultados apoyan el uso tradicional de estos materiales en padecimientos asociados al tratamiento de infecciones bacterianas.
Subject(s)
Anti-Bacterial Agents/pharmacology , Bignoniaceae/chemistry , Plant Extracts/pharmacology , Malpighiaceae/chemistry , Psidium/chemistry , Gram-Negative Bacteria , Gram-Positive Bacteria , Dietary Supplements , Phenols/analysis , Fruit/chemistry , Microbial Sensitivity TestsABSTRACT
Alimentos funcionais apresentam componentes fisiologicamente ativos, capazes de promover a saúde, além dos benefícios nutricionais. A uva e seus derivados, por apresentar compostos com alto potencial bioativo, especialmente o resveratrol, foram escolhidos como objeto de pesquisa na avaliação do conhecimento do consumidor em relação aos alimentos funcionais. A população de estudo escolhida foi a comunidade de três instituições universitárias da cidade de Maringá, Estado do Paraná. Foi elaborado um questionário e aplicado a um total de 485 indivíduos. O alimento mais aceito e mais consumido foi o suco de uva (51% de aceitação), seguido do vinho tinto (49% de aceitação). A bebida de soja sabor uva, alimento que apresentou menor popularidade, nunca foi experimentada por 13% da população entrevistada e 40% nunca consomem este alimento. Dos entrevistados, 48% pareceram desconhecer ou não estar certos das alegações de saúde propostas no questionário. Tal desconhecimento refere-se à relação do vinho e compostos fenólicos com efeitos sobre a pressão arterial, osteoporose, diurese e antidepressão. Apesar do interesse e curiosidade quanto aos alimentos funcionais, os jovens entrevistados ainda não têm conhecimento suficiente sobre os benefícios dos alimentos funcionais à saúde humana.
Functional foods have physiologically active components capable of promoting health, and nutritional benefits. The grape and its derivatives, due to the compounds with high bioactive potential, especially resveratrol, were chosen as a research subject in the assessment of consumer knowledge regarding functional foods. The study population was the community of three universities in the city of Maringá, Paraná State. A questionnaire was developed and applied to a total of 485 individuals. The food most accepted and consumed was grape juice (51% acceptance), followed by red wine (49% acceptance). The soy drink grape-flavored, food with the lowest popularity has never been tried by 13% of the population interviewed, and 40% never consume this food. Of the interviewees, 48% seemed to be unaware or not sure of the health claims proposed in the questionnaire. This ignorance refers to the relationship of wine and phenolic compounds with positive effects on the blood pressure, osteoporosis, diuresis and depression. Although the interest and curiosity about the functional food, young interviewed still do not know enough about the benefits of functional foods on human health.