ABSTRACT
A 56-year-old male patient presented with a slow-growing, elevated, smooth, white corneal mass. The mass was excised by performing an alcohol-assisted keratoepitheliectomy and sent for histopathological examination. Subepithelially, closely packed spindle cells in 揻eather-stitched� or storiform pattern were seen. Immunohistochemically, the cells stained negatively for CD-34 and S-100 and focal positivity was seen for vimentin. Based on the morphology and immunochemical staining, a diagnosis of corneal fibroma was made. No recurrence was seen. Corneal fibroma is an exceedingly rare, benign tumor and possibly lies on the same spectrum as corneal keloid and hypertrophic cicatrix. Surgical resection is usually curative.
ABSTRACT
PURPOSE: To assess the characteristics and treatments of ocular surface squamous neoplasms (OSSN). METHODS: We analyzed four representative cases of squamous neoplasms present on the ocular surface and discussed a new paradigm for the diagnosis and management of such lesions. CONCLUSIONS: Conjunctival and corneal tumors differentiated to squamous cells are rare. OSSN has various clinical appearances, and because OSSN itself is either malignant or has potential to become malignancy, precise discrimination and adequate treatment methods are necessary. We hope that the results from this study provide a basic source of information for diagnosing and treating OSSN.