COVID 19 INFECTION IN A PATIENT NEWLY DIAGNOSED WITH HIV/TB COINFECTION – A CASE REPORT

HIV/TB coinfection, COVID 19 with HIV/TB, immune reconstitution inflammatory syndrome (IRIS), TB lymphadenopathy

Influence of the coronavirus disease 2019 pandemic on maternal breastfeeding for very low birth weight infants / 中国当代儿科杂志

OBJECTIVES@#To investigate the changes in the rate and volume of mother's own milk (MOM) feeding for very low birth weight infants (VLBWIs) hospitalized during the prevention and control of the coronavirus disease 2019 (COVID-19) pandemic.@*METHODS@#A retrospective analysis was performed on the medical data of the VLBWIs with a gestational age of <32 weeks who were born and admitted to the Neonatal Intensive Care Unit of Nanjing Maternal and Child Health Hospital from January 2019 to December 2020. The changes in the rate and volume of MOM feeding for VLBWIs during hospitalization were examined.@*RESULTS@#A total of 301 VLBWIs were enrolled. According to the timing of COVID-19 outbreak, these infants were divided into a pre-CIVID-19 group with 205 VLBWIs and a post-COVID-19 group with 96 VLBWIs. Compared with the pre-CIVID-19 group, the post-COVID-19 group had a significantly lower rate of MOM feeding within 28 days after birth and during hospitalization (P<0.05), a significantly lower volume of MOM feeding within 0-7 days, 0-14 days, and 0-28 days after birth (P<0.05), and significantly higher incidence rates of moderate-to-severe bronchopulmonary dysplasia and feeding intolerance (P<0.05).@*CONCLUSIONS@#The COVID-19 pandemic has a significant impact on MOM feeding for VLBWIs, and there are significant reductions in the rate and volume of MOM feeding for VLBWIs within 28 days after birth, as well as a significant reduction in the rate of MOM feeding during hospitalization.

Perspectivas filosóficas a partir del problema del suicidio / Philosophical perspectives from the problem of suicide / Perspectivas filosóficas a partir do problema do suicídio

Resumen Varias de las actuales discusiones bioéticas parten del supuesto de que tenemos absoluto dominio/disposición sobre nuestro cuerpo. Bajo la tesis de la autonomía, del dominio de la vida propia y de la libertad para hacer cualquier cosa, al menos con nuestro cuerpo, se suele justificar la bondad o legitimidad de actos como el suicidio y la eutanasia. Supuesto lo anterior, el trabajo aborda la cuestión de la naturaleza de la disposición -principal atributo del dominio o propiedad- sobre el cuerpo. Se argumentará sobre la base de la teoría de Tomás de Aquino y de la exposición de Immanuel Kant, muchas veces consideradas, erróneamente a mi juicio, como doctrinas rivales. El escrito estará orientado a revisar las relaciones del moderno principio de autonomía con la problemática de la moralidad del suicidio.

Abstract Many of the actual bioethical discussions start from the assumption that we have absolute dominance/disposition over our body. Based on the thesis of autonomy, control over one's own life and the freedom to do anything, at least with one's body, the goodness or legitimacy of acts such as suicide and euthanasia are often justified. Considering the last statements, this paper seeks to approach the question of the nature of the disposition -main attribute of dominion or property- over the body. It will be argued on the basis of Thomas Aquinas' theory and Immanuel Kant's exposition, often wrongly considered, in my opinion, as rival doctrines. The whole writing will be oriented to review the relations of the modern principle of autonomy with the problem of the morality of suicide.

Resumo Várias das atuais discussões bioéticas partem do pressuposto de que temos absoluto domínio/disposição sobre nosso corpo. Sob a tese da autonomia, do domínio da vida própria e da liberdade para fazer qualquer coisa, ao menos com nosso corpo, costuma-se justificar a bondade ou legitimidade de atos como o suicídio e a eutanásia. Levando em consideração o anterior, este trabalho pretende abordar a questão da natureza da disposição -principal atributo do domínio ou da propriedade- sobre o corpo. Argumenta-se com base na teoria de Tomás de Aquino e na exposição de Immanuel Kant, muitas vezes conceituadas, erroneamente, em minha opinião, como doutrinas rivais. Este texto estará orientado a revisar as relações do moderno princípio de autonomia com a problemática da moralidade do suicídio.

Propuesta de asignatura Generalidades de la Estimulación Magnética Transcraneal para técnicos superiores de Neurofisiología Clínica / Course proposal Generalities of Transcranial Magnetic Stimulation for senior technicians of Clinical Neurophysiology

Introducción: Recientemente se inició la formación de profesionales en una nueva modalidad de Programas Técnico Superior de Ciclo Corto, en la especialidad de Neurofisiología Clínica. Esto responde a la necesidad de la formación de profesionales de la salud en el estudio de las enfermedades neurológicas. La estimulación magnética transcraneal constituye una herramienta importante en el diagnóstico y tratamiento de estas enfermedades. Sin embargo, se carece de un programa para la formación de los estudiantes en el estudio y aplicación de esta técnica. Objetivo: Diseñar un programa de curso propio sobre generalidades de la estimulación magnética transcraneal, para estudiantes de primer año de Neurofisiología Clínica. Métodos: Se realizó una investigación didáctica metodológica utilizando los métodos empíricos y teóricos observación, histórico lógico, estudio documental y bibliográfico, dialéctico, análisis y síntesis, inducción y deducción. Resultados: Se propuso un programa para curso propio que se estructuró en siete temas, con carácter presencial y duración de 32 horas. Se presentaron los contenidos por temas, objetivos, conocimientos esenciales a adquirir, habilidades principales a dominar y sistema de evaluación. Conclusiones: La aplicación de este programa contribuye al desarrollo de habilidades y el desempeño exitoso de los profesionales en formación, en el campo del conocimiento de la técnica de estimulación magnética transcraneal para el diagnóstico y tratamiento de las enfermedades neurológicas(AU)

Introduction: Recently began the training of professionals in a new modality of short-cycle Higher Technical Programs, in the specialty of Clinical Neurophysiology. This responds to the need of training health professionals in the study of neurological diseases, whose incidence rates have increased in recent years. Transcranial magnetic stimulation is an important tool in the diagnosis and treatment of these diseases. However, there is a lack of a program for the training of students in the study and application of this technique. Objective: Tto design an own course program on the generalities of transcranial magnetic stimulation, for first-year students of Clinical Neurophysiology. Method: A methodological didactic research was carried out using the empirical and theoretical methods, observation, logical historical, documentary and bibliographic study, dialectic, analysis and synthesis, induction and deduction. Results: A program for the course was proposed, structured in seven topics, with a face-to-face character and a duration of 32 hours. The contents were presented by topics, objectives, essential knowledge to acquire, main skills to master and an evaluation system. Conclusions: The application of this program contributes to the development of skills and the successful performance of professionals in training, in the field of knowledge of the transcranial magnetic stimulation technique for the diagnosis and treatment of neurological diseases(AU)

Introdução: Iniciou recentemente a formação de profissionais numa nova modalidade de Cursos Técnicos Superiores de Ciclo Curto, na especialidade de Neurofisiologia Clínica. Isso responde à necessidade de formação de profissionais de saúde no estudo das doenças neurológicas. A estimulação magnética transcraniana é uma ferramenta importante no diagnóstico e tratamento dessas doenças. No entanto, falta um programa de treinamento dos alunos no estudo e aplicação desta técnica. Objetivo: Desenhar um programa próprio sobre as generalidades da estimulação magnética transcraniana, para alunos do primeiro ano de Neurofisiologia Clínica. Método: Realizou-se uma investigação metodológica didática utilizando os métodos empírico e teórico de observação, histórico lógico, estudo documental e bibliográfico, dialética, análise e síntese, indução e dedução. Resultados: Foi proposto um programa de curso próprio, estruturado em sete temas, com caráter presencial e duração de 32 horas. Os conteúdos foram apresentados por tópicos, objetivos, conhecimentos essenciais a adquirir, competências principais a dominar e um sistema de avaliação. Conclusões: A aplicação deste programa contribui para o desenvolvimento de competências e o desempenho bem sucedido de profissionais em formação, no domínio do conhecimento da técnica de estimulação magnética transcraniana para o diagnóstico e tratamento de doenças neurológicas(AU)

Hans Bellmer e sua pequena anatomia da imagem: corpo próprio e psicanálise / Hans Bellmer and your little anatomy of the image: own body and psychoanalysis / Hans Bellmer et sa petite anatomie de limage: propre corps et psychanalyse / Hans Bellmer y su pequeña anatomía de la imagen: cuerpo propio y psicoanálisis

Resumo Em Petite Anatomie de l'image (1949), o artista Hans Bellmer formula uma teoria da imagem do corpo que parte da premissa de que a anatomia humana é subjetiva, imaginária e até permeada por estados psicopatológicos. Assim, Bellmer mostra um corpo interno desenhado por traços de memória e por uma imagem puramente psíquica, ou seja, ele coloca em cena o corpo pulsional. Diante dessa obra, perguntamos o que o artista ensina à psicanálise lacaniana sobre o corpo próprio e sua representação, conceitos importantes para a clínica. Nesse sentido, uma indicação valiosa orientará esta discussão: o segredo da imagem é a castração.

Abstract In Petite Anatomie de l'image (1949), Hans Bellmer, an artist, describes a body image theory that assumes human anatomy to be subjective, imagined, and even permeated by psychopathological states. Thus, Bellmer shows an inner body designed by memory traces and purely mental image, that is, he introduces an instinctual body. Based on his work, we analyze what artists can teach lacanian psychoanalysis regarding one's own body and its representation, as they are important concepts for work in the clinic. Thus, a valuable indication guides this discussion: the secret of image is castration.

Résumé Dans Petite Anatomie de l'image (1949), l'artiste Hans Bellmer formule une théorie de l'image du corps partant du principe que l'anatomie humaine est subjective, imaginaire, et même imprégnée d'états psychopathologiques. Ainsi, Bellmer montre un corps interne, dessiné par des traces de mémoire et par une image purement psychique, c'est-à-dire qu'il met le corps pulsionnel dans la scène. Devant cet oeuvre, nous demandons ce que l'artiste enseigne au psychanalyste lacanien sur le corps et sa représentation, de concepts importants pour la clinique. L'affirmation suivante guidera notre discussion : le secret de l'image est la castration.

Resumen En Petite Anatomie de l'image (1949), el artista Hans Bellmer plantea una teoría de la imagen del cuerpo, que parte de la premisa de que la anatomía humana es subjetiva, imaginaria e incluso permeada por estados psicopatológicos. Así Bellmer muestra un cuerpo interno, dibujado por rasgos de memoria y por una imagen puramente psíquica, es decir, pone en escena el cuerpo pulsional. Con base en esta obra, nos preguntamos qué enseña el artista al psicoanálisis lacaniano en cuanto al cuerpo propio y su representación, conceptos importantes para la clínica. En este sentido, una valiosa indicación orientará esta discusión: el secreto de la imagen es la castración.

Relación entre el conocimiento y recomendación del baby led weaning en nutricionistas de atención primaria, en las ciudades de Coquimbo y La Serena, Chile / Relationship between knowledge and recommendations of baby-led weaning in primary care settings in the cities of Coquimbo and La Serena, Chile

Introducción: La OMS recomienda la entrega de lactancia materna exclusiva hasta los 6 meses, debiendo a esta edad introducir la alimentación complementaria mediante una papilla de carne con verduras o una nueva técnica de alimentación llamada baby led weaning (BLW). Objetivo general: relacionar el nivel de conocimiento con la recomendación de la técnica BLW en Nutricionistas de atención primaria de salud de las ciudades de Coquimbo y La Serena. Métodos: se aplicó un cuestionario presencial o vía Google forms a nutricionistas, el cual evaluó el nivel de conocimiento y la recomendación (actual y pasada) del BLW. Resultados: el 57,4% de las nutricionistas ha recomendado alguna vez el BLW y el 38,3% tiene un conocimiento suficiente de la técnica, según el análisis de regresión las y los nutricionistas de la ciudad de La Serena tienen un mayor nivel de recomendación del BLW. Conclusión: El BLW es una técnica de alimentación conocida por los y las nutricionistas, sin embargo, refieren un bajo nivel de recomendación y conocimiento, siendo la papilla tradicional la técnica más recomendada en la consulta nutricional de los 5 meses.

Introduction: The WHO recommends exclusive breast-feeding up to 6 months, at which time complementary feeding with pureed meats and vegetables or a new feeding technique called baby led weaning (BLW) begins. General objective: to relate the level of knowledge of the BLW recommendation among primary health care nutritionists in the cities of Coquimbo and La Serena, Chile. Methods: a face-to-face questionnaire or google forms, which assessed knowledge level and recommendation (current and past) of the BLW was answered by nutritionists. Results: 57.4% of the nutritionists had recommended the BLW and 38.3% had sufficient knowledge of the technique. According to regression analysis, nutritionists from the city of La Serena recommended BLW more often than those from Coquimbo. Conclusion: The BLW was a feeding technique familiar to nutritionists, however they had a low level of recommendation and knowledge, with the traditional pureed meat with vegetables the most recommended technique in the 5-month nutritional consultation.

Measurement of equivalence using a patient-reported daily pain diary across three smartphone devices

Background:Patient-reported outcomesplay an essential role in evaluating the results of clinical trials. As technological advances are made throughout the industry, pharmaceutical sponsors’ ability to collect field-based patient data has greatly increased. Recently, many clinical trials areutilizing varying modes of data capture in order to enable maximum flexibility. Given the regulatory concern over the equivalence of mixed modes of administration, the need to research the use of varying devices is essential.Methods:This study reviewedthree handheld smartphone devices for conceptual equivalence and conducted usability for standard questions used in a daily pain diary. Out of ten participants, 7 were females and 3 were males with age ranging from27-70 years, diagnosed with chronic painor fibromyalgia, completed the same pain diary on three different smartphone devices.Results:Overall, participants reported no differences between these three smartphone devices and found the presentation of the diary content to be similar, if not identical, on all three devices. Conclusions: Device type had no impact on the presentation of the diary content or participants’ understanding of the diary questions

Case reports for embryo banking: for women who want their own

Out of the many challenges in management of female factor infertility, poor responders and low response to stimulation in aged and even younger women, seems to be a common problem. It is very difficult to offer one particular management strategy or treatment protocol for optimum outcome in this group of women of poor responders. In a low resource set up, IVF (In vitro Fertilization) specialist doctors usually face a challenge in treating women with poor/ low ovarian reserve as ovum / gamete donation is considered as a taboo in various sections of society even today. Hence women insist on having an offspring of "their own" and vehemently deny ovum / gamete donations. In this article we discuss 2 cases of poor ovarian reserve retrospectively, who underwent multiple cycles of controlled ovarian hyperstimulation for embryo banking and ultimately achieved pregnancy. Both patients achieved pregnancy with the method of embryo banking. Embryo banking should be considered and discussed. Various articles have discussed the advantages and disadvantages of embryo banking or even oocytes accumulation. The advantages of this technique is patients with poor/low ovarian reserve get a chance to be pregnant with their own oocytes and also have a chance for vitrification of residual embryos. Another advantage in such patients is that the embryos can undergo PGS (Preimplantation Genetic Screening) techniques in cases of suspected genetic disorders. The disadvantage in a low resource set up like India is the cost of the treatment. Nevertheless, embryo banking and accumulation of oocytes should be given as an option for treatment of poor/ low ovarian reserve and could be considered as a ray of hope for all future mothers hoping for a child of "their own".

Sustitución de nombre, uso cínico del lenguaje y constitución de subjetividad en adolescentes Hip Hop¹: un Otro name / Replacement of name, cynical use of language and constitution of subjectivity in adolescents Hip-Hop: Other name / Substituição do nome, uso cínico da linguagem e constituição da subjetividade em adolescentes Hip Hop: um Outro nome

Con el objetivo de encontrar evidencias sobre cómo se dan procesos de constitución de subjetividad en adolescentes que integran agrupaciones juveniles de ciudad (AJC), cómo dichas agrupaciones inciden en esos procesos constitutivos y como se las arreglan los adolescentes para resolver sus dilemas, realizamos una investigación-intervención de orientación clínica en Argentina y Colombia durante los años 2013-2016. Con la aplicación del método de intervención cínica a la investigación académica (MICAP) a través de espacios de habla, entrevistas de orientación clínica, y diarios (de bordo y clínico) conseguimos obtener discursos singulares de adolescentes integrantes AJC (48 en total). De esos discursos extrajimos salidas de constitución subjetiva que tienen los adolescentes. También obtuvimos, a través de observaciones y entrevistas semiestructuradas, discursos particulares que sobre adolescentes y jóvenes se tienen en algunas ciudades de esos países. Ambos discursos nos permitieron identificar que estos adolescentes presentan comportamientos distantes de las identidades cristalizadas que les ubican, por ejemplo, como consumistas, violentos, soñadores, negligentes, apolíticos, entre otros y que, para algunos, la resolución a los conflictos advenidos con la adolescencia y relacionadas con las dinámicas de las AJC se da a través de la sustitución de sus nombres es decir, elaborando nuevas nominaciones y con ellas realizando procesos de importancia en la constitución de su subjetividad como la identificación, la constitución de lazo social y la manifestación de divergencias con el mundo adulto. Presentamos aquí dos casos de sustitución de nombres con apodos que develaron tendencias cínicas, criticidad y actitudes contestarías ante el mundo adulto y el universo de las normas.

In order to find evidence on how subjectivity processes occur in adolescents that make up youth city groups (AJC), how these groupings influence such constitutive processes, and how adolescents can solve their dilemmas, we conducted an intervention-oriented clinical investigation in Argentina and Colombia during the years 2013-2015. With the application of the cynical intervention method to academic research (MICAP), through speech spaces, clinical guidance interviews and journals (board and clinical), we were able to obtain singular speeches from AJC adolescents (48 in total). From these discourses, we extract the subjective exits of these adolescents. We also obtained, through observations and semi-structured interviews, private speeches that adolescents and young people have in two cities of these countries. Both discourses allowed us to identify that these subjects present behaviors that are far from the crystallized identities that put them, for example, as consumers, violent, dreamy, negligent, apolitical, among others, and that for some, conflict resolution of adolescence and related to the dynamics of the AJC occurs through the substitution of their own names, that is, elaborating new appointments and with them performing processes of importance in the constitution of their subjectivity as the identification, the constitution of the social bond and the manifestation of divergences with the adult world. We present here two cases of substitution of names with nicknames that revealed cynical tendencies, criticality and defiant attitudes of the adult world and the universe of norms.

Com o objetivo de encontrar evidências sobre como ocorrem processos de constituição de subjetividade em adolescentes que compõem agrupamentos juvenis de cidade (AJC), como esses agrupamentos influenciam tais processos constitutivos e como os adolescentes conseguem resolver seus dilemas, realizamos uma investigação-intervenção de orientação clínica na Argentina e na Colômbia durante os anos 2013-2015. Com a aplicação do método de intervenção cínica à pesquisa acadêmica (MICAP), por meio de espaços de fala, entrevistas de orientação clínica e diários (de bordo e clínico), conseguimos obter discursos singulares de adolescentes membros de AJC (48 no total). A partir desses discursos extraímos as saídas subjetivas desses adolescentes. Também obtivemos, através de observações e entrevistas semiestruturadas, discursos particulares que adolescentes e jovens têm em duas cidades desses países. Ambos os discursos nos permitiram identificar que tais sujeitos apresentam comportamentos distantes das identidades cristalizadas que os colocam, por exemplo, como consumidores, violentos, sonhadores, negligentes, apolíticos, entre outros, e que, para alguns, a resolução de conflitos da adolescência e relacionada à dinâmica do AJC ocorre através da substituição de seus nomes próprios, isto é, elaborando novas nomeações e com elas realizando processos de importância na constituição de sua subjetividade como a identificação, a constituição do vínculo social e a manifestação de divergências com o mundo adulto. Apresentamos aqui dois casos de substituição de nomes com apelidos que revelaram tendências cínicas, criticidade e atitudes contestadoras do mundo adulto e do universo das normas.

Tipo mais prevalente de abuso aos idosos e sua correlação com depressão do idoso / Tipo más prevalente de abuso a los ancianos y su correlación con depresión del anciano / Most prevalent type of elder abuse and its correlation with elder depression

Resumo Objetivo: O objetivo deste estudo foi identificar o tipo mais prevalente de abuso aos idosos na Coréia do Sul. Este estudo também analisou que tipo de abuso aos idosos mais afetou a depressão e depois discutiu contramedidas sociais em relação aos tipos prevalentes de abuso aos idosos. Métodos: Trata-se de um estudo descritivo e os dados foram coletados por meio de amostragem por conveniência. Setenta e sete participantes tinham 60 anos ou mais e não tinham deficiência mental ou transtorno depressivo. Cinco tipos diferentes de abuso aos idosos (verbal, emocional, físico, financeiro e negligência) foram medidos, bem como sintomas depressivos. Foi utilizada estatística descritiva para determinar o tipo mais prevalente de abuso aos idosos na Coréia do Sul. Além disso, utilizaram-se testes de correlação bivariada e regressão múltipla para entender a relação entre os tipos de abuso aos idosos e depressão do idoso. Resultados: Entre os cinco tipos de abuso aos idosos, o abuso verbal, emocional e negligência foram mais prevalentes do que os abusos físicos e financeiros. De acordo com a análise bivariada, o abuso emocional e o abuso verbal foram significativamente relacionados à depressão do idoso. Conclusão Os tipos invisíveis de abuso aos idosos, como abuso emocional, verbal e negligência, foram mais prevalentes do que os tipos visíveis, como abuso físico e financeiro. Esses tipos de abuso também foram significativamente correlacionados com a depressão do idoso. Este estudo permite futuros estudos intervencionais para melhorar a percepção dos idosos sobre o abuso e, assim, prevenir o desenvolvimento da depressão dos idosos.

Resumen Objetivo: El objetivo de este estudio fue identificar el tipo más prevalente de abuso a los ancianos en Corea del Sur. Este estudio también analizó qué tipo de abuso a los ancianos más afectó la depresión y después discutió contramedidas sociales con relación a los tipos prevalentes de abuso a los ancianos. Métodos: Se trata de un estudio descriptivo y los datos fueron recolectados a través de muestreo por conveniencia. Setenta y siete participantes tenían 60 años o más y no tenían deficiencia mental o trastorno depresivo. Cinco tipos diferentes de abuso a los ancianos (verbal, emocional, físico, financiero y negligencia) se midieron, así como síntomas depresivos. Se utilizó la estadística descriptiva para determinar el tipo más prevalente de abuso a los ancianos en Corea del Sur. Además, se utilizaron pruebas de correlación bivariada y regresión múltiple para entender la relación entre los tipos de abuso a los ancianos y la depresión del anciano. Resultados: Entre los cinco tipos de abuso a los ancianos, el abuso verbal, emocional y la negligencia fueron más prevalentes que los abusos físicos y financieros. De acuerdo con el análisis bivariado, el abuso emocional y el abuso verbal fueron significativamente relacionados con la depresión del anciano. Conclusión: Los tipos invisibles de abuso a los ancianos, como abuso emocional, verbal y negligencia, fueron más prevalentes que los tipos visibles, como abuso físico y financiero. Estos tipos de abuso también se correlacionaron significativamente con la depresión del anciano. Este estudio permite futuros estudios intervencionistas para mejorar la percepción de los ancianos sobre el abuso y así evitar el desarrollo de la depresión de los ancianos.

Abstract Objective: The purpose of this study was to identify the most prevalent type of elder abuse in S. Korea. This study also examined which type of elder abuse most affected elder depression and then discussed social countermeasures toward the prevalent types of elder abuse. Methods: This was a descriptive study and the data were collected via a convenience sampling method. Seventy-seven study participants were 60 years old or above and did not have mental disabilities or depression disorder. Five different types of elder abuse (verbal, emotional, physical, financial, and neglect) were measured along with their depressive symptoms. Descriptive statistics were used to determine the most prevalent type of elder abuse in S. Korea. Also, bivariate correlation and multiple regression were utilized to understand the relationship between types of elder abuse and elder depression. Results: Among the five types of elder abuse, verbal, emotional, and neglect abuse were more prevalent than physical and financial abuse. According to the bivariate analysis, emotional abuse and verbal abuse were significantly related with elder depression. Conclusion: Invisible types of elder abuse such as emotional, verbal, and neglect abuse were more prevalent than visible types such as financial and physical abuse. These abuse types were also significantly correlated with elder depression. This study warrants future interventional studies to improve elders' perception of elder abuse and thus prevent the development of elder depression.

Effect of periodontitis patient s own tissue nucleic acid on expression of nlrp3 mRNA in murine macrophages and its significance / 吉林大学学报(医学版)

Objcctivc: To detect the mRNA expression leveb of inflammatory-related factors NLRP3, caspase-1. IL-lp. and 1L-18 in the murine macrophages infected by periodontitis patient's own tissue nucleic acid, and to discuss the effects of penodontitis patient' s own tissue nucleic acid on the inflammation-related factors in the macro. hacs. Methods: The mflammator. . eriodontal tissue sam. les were collected durin . eriodontal fla. surcr. of the chronic periodontitis patients, and the healthy periodontal tissue samples were collected from the patients without any periodontal diseases undergoing crown lengthening surgery. Then the total RNA from gingival tissue was extracted and reversely transcribed into cDNA. The cultured mouse macrophages RAW264. 7 were divided into control group and experiment group, then the healthy periodontal tissue cDNA and inflammatory periodontal tissue cDNA (the cDNA at a concentration of 1 mg • L ) were added into the RAW264. 7 cells, respectively. Real-time PCR was used to detect the mRNA expression levels of NLRP3 . Caspase-1. 1L-1(3. and 1L-18 in the macrophages in various groups at 4. 6 and 8 h after incubation. Rcsilts: The microscope observation showed that the mouse macrophages RAW264. 7 grew well with round and polygon shapes, clear cytoplasm, and full cell body. Compared with control group, the expression levels of NLRP3. Caspase-1. 1L-10. and 1L-18 mRNA in the RAW264. 7 cells in experiment group at 4. 6. and 8 h were increased significantly ( P<0. 05 or P<0. 01). and the expresaon levels of NLRP3. Caspase-1. 1L-10. and 1L-18 mRNA in RAW264.7 cells at 6 h in experiment group were the highest. Ccoclusico. The periodontitis patient's own tissue nucleic acids can promote the mRNA expressions of inflammation- related factors in the RAW264. 7 cells, suggesting that the periodontitis patient' s own tissue nucleic acid has an immunomodulatory effect on the activation of RAW264. 7 cells.

Effect of periodontitis patient's own tissue nucleic acid on expression of NLRP3 mRNA in murine macrophages and its significance / 吉林大学学报(医学版)

Objective:To detect the mRNA expression levels of inflammatory-related factors NLRP3, caspase-1, IL-1β, and IL-18in the murine macrophages infected by periodontitis patient's own tissue nucleic acid, and to discuss the effects of periodontitis patient's own tissue nucleic acid on the inflammation-related factors in the macrophages.Methods:The inflammatory periodontal tissue samples were collected during periodontal flap surgery of the chronic periodontitis patients, and the healthy periodontal tissue samples were collected from the patients without any periodontal diseases undergoing crown lengthening surgery.Then the total RNA from gingival tissue was extracted and reversely transcribed into cDNA.The cultured mouse macrophages RAW264.7were divided into control group and experiment group, then the healthy periodontal tissue cDNA and inflammatory periodontal tissue cDNA (the cDNA at a concentration of 1mg·L-1) were added into the RAW264.7cells, respectively.Real-time PCR was used to detect the mRNA expression levels of NLRP3, Caspase-1, IL-1β, and IL-18in the macrophages in various groups at 4, 6and 8hafter incubation.Results:The microscope observation showed that the mouse macrophages RAW264.7grew well with round and polygon shapes, clear cytoplasm, and full cell body.Compared with control group, the expression levels of NLRP3, Caspase-1, IL-1β, and IL-18mRNA in the RAW264.7cells in experiment group at 4, 6, and 8hwere increased significantly (P＜0.05or P＜0.01) , and the expression levels of NLRP3, Caspase-1, IL-1β, and IL-18 mRNA in RAW264.7 cells at 6 hin experiment group were the highest.Conclusion:The periodontitis patient's own tissue nucleic acids can promote the mRNA expressions of inflammation-related factors in the RAW264.7cells, suggesting that the periodontitis patient's own tissue nucleic acid has an immunomodulatory effect on the activation of RAW264.7cells.

Prevalence of Geriatric Giants Among Older People in Kelantan Malaysia

@#Introduction: Geriatric Giants are the impairment that appear in older people. It comprises of impaired cognition, urinary incontinence, instability, fall and immobility. The aim of this study is to determine the prevalence of Geriatric Giants among older people living in three different living environment; own home, pondok and old folks home. Methods: This comparative study involved 471 respondents from Kelantan. There were 157 participants each from own home, pondok and old folks home. The prevalence of Geriatric Giants were determine by 10 minutes comprehensive screening which was developed to diagnose and manage the Geriatric Giants (WHO, 2007) and prevalence were compared using chi-square tests or Fisher exact test. Results: Prevalence of dementia among respondents of old folks home (11.5%), pondok (6.4%) and own home (0.6%). Prevalence of urinary incontinence among respondents of own home (22.3%), old folks home (16.6%) and pondok (14.0%). Prevalence of instability among respondents of old folk home (31.2%), pondok (27.4%) and own home (14.0%). Prevalence of fall among respondents of pondok (33.1%), old folks home (24.25) and own home (19.7%). Old folk home respondents had the highest prevalence of moderate and severe immobility There were significant difference in prevalence of dementia ((Fisher exact p value <0.001), instability (χ2(2)=13.957,p=0.001), fall (χ2(2)=7.629,p=0.022) and mild and moderate immobility. Conclusion: Old folks home respondents had more prevalence of Geriatric Giants compared to their other counter parts.

A relação entre as transferências governamentais, a arrecadação tributária própria e o índice de educação dos municípios do estado de Minas Gerais / La relación entre las transferencias gubernamentales, la recaudación de impuestos y el índice de educación de los municipios del estado de Minas Gerais / Relation between the government transfers, own tax collection and education index of the municipalities of the state of Minas Gerais

Resumo: Considerando as mudanças proporcionadas aos municípios brasileiros, desde a promulgação da Constituição Federal de 1988, objetivou-se verificar a relação entre as transferências governamentais, a arrecadação tributária própria e o índice de educação dos municípios do estado de Minas Gerais (2009 a 2013), partindo da hipótese de que uma maior disponibilidade de recursos financeiros impactaria positivamente a qualidade da educação municipal. As variáveis do estudo foram testadas por meio da análise de variância em blocos casualizados, correlação de Spearman, análise de clusters de k-médias e regressão linear múltipla. Entre as inferências deste estudo, destaca-se a falta de associação entre o grau de autonomia financeira e os investimentos em educação, e o achado de que o quantitativo de receitas tributárias e o percentual adicional de investimento em educação não impactam o índice de educação.

Resumen: Considerando que las modificaciones son proporcionadas a los municipios brasileños, desde la promulgación de la Constitución Federal de 1988, que alteró la asignación de recursos públicos a la educación, los municipios brasileños pasaron a recibir más recursos del gobierno, así como aumentar el porcentaje de la asignación municipal invertida en el área de educación. Así, en este estudio se objetivó verificar la relación entre las transferencias gubernamentales, la recaudación de impuestos propia y el índice de educación de los municipios del estado de Minas Gerais (2009 a 2013), partiendo de la hipótesis de que una mayor disponibilidad de recursos financieros impactaría positivamente la calidad de la educación municipal. Las variables del estudio se probaron por medio del análisis de varianza en bloques casualizados, correlación de Spearman, análisis de clusters de k-medias y regresión lineal múltiple. Entre las inferencias de este estudio, se destaca la falta de asociación entre el grado de autonomía financiera y las inversiones en educación, y el hallazgo de que el cuantitativo del aumento de impuestos y el porcentaje adicional de inversión en educación no impactan el índice de educación.

Abstract Considering the changes in Brazilian municipalities since the Federal Constitution of 1988, this study sought to verify the relationship between government transfers, own tax collection and the education index of municipalities of the state of Minas Gerais (2009 to 2013). The hypothesis adopted was that a greater financial resources availability would have a positive impact on the municipal education's quality. The study variables were tested using randomized block variance analysis, Spearman's correlation, k-rates clusters' analysis and multiple linear regression. Among the results obtained, the study highlights the lack of connection between the degree of financial autonomy and the investments in education, as well as it finds that the amount of revenues from taxes and the extra percentage of investment do not affect the education index.

Application of bring your own device in healthcare institutions / 中华医院管理杂志

Bring your own device (BYOD) has become popular as it empowers medical practitioners to use their own devices for communication,mobile rounds,real-time EMR query,selflearning and auxiliary diagnosis.Based on implementation experiences of BYOD at home and overseas healthcare institutions,this paper recommended domestic institutions on BYOD planning and deployment as follows:restructuring of their wireless networks and access control;better device supervision;open BYOD portal;and protection of both staff privacy and data security.This effort provides insights for BYOD development in China's healthcare institutions.

Fenomenologia e Educação Física: uma revisão dos conceitos de corpo e motricidade / Phenomenology and Physical Education: a review of the body and motricity's concepts / Fenomenología y Educación Física: una revisión del conceptos de cuerpo y motricidad

Este trabalho caracteriza-se como uma revisão de literatura, um estudo bibliográfico, acerca dos conceitos de corpo e motricidade existentes na Fenomenologia da Percepção, de Merleau-Ponty. O objetivo deste trabalho foi evidenciar os conceitos de corpo e motricidade em Merleau-Ponty e identificar implicações para a área da Educação Física. A pesquisa na Fenomenologia de Merleau-Ponty aponta para um redimensionamento do olhar sobre o ser humano e a forma de ser no mundo. O movimento é compreendido como linguagem sensível que manifesta a intenção do ser em relação ao mundo, ao espaço, aos outros, às coisas, favorecendo a uma ampliação na concepção de corpo que historicamente se instituiu na Educação Física: do corpo enquanto objeto de estudo para também considerá-lo como corpo sujeito. Além de ser orgânico, o corpo é social, cultural e histórico e aprende por meio de sua corporeidade.

This work is characterized as a literature review, a bibliographic study, about the existing body and motricity concepts in the Phenomenology of Perception, from Merleau-Ponty. The objective of this study was to demonstrate the concepts of body and motricity in Merleau-Ponty and identify implications for the field of Physical Education. The research in Merleau-Ponty's Phenomenology indicates a reshaping the look on the human being and the way of being in the world. The movement is understood as sensitive language that expresses the being's intention in relation to the world, to space, to others, to things, favoring an amplification in the concept of the body that historically was instituted to Physical Education: the body as an object of study; to also consider it as subject body. Besides being organic, the body is social, cultural and historical.

Esta obra se caracteriza como una revisión de la literatura, un estudio bibliográfico, sobre los conceptos de cuerpo y motricidad existente en la Fenomenología de la Percepción, en Merleau-Ponty. El objetivo de este estudio fue demostrar los conceptos de cuerpo y motricidad en Merleau-Ponty y identificar las implicaciones para el campo de la Educación Física. La investigación en la Fenomenología de Merleau-Ponty indica una nueva mirada en el ser humano y como estar en el mundo. El movimiento se entiende como un lenguaje sensible manifestando la intención de estar en relación con el mundo, al espacio, a los demás, a las cosas, favoreciendo una ampliación en el concepción del cuerpo que históricamente fue instituido en la Educación Física: el cuerpo como un objeto de estudio; para también considerarlo como un cuerpo sujeto. Además de ser orgánico, el cuerpo es social, cultural e histórico.

Cara y ceca de la injusticia: visión judía de los linchamientos / Heads and tails of injustice: Jewish Vision of lynchings

El análisis desde la óptica judía del fenómeno de los linchamientos actuales en el marco de una profunda impunidad e inseguridad social, indica que el motivo de dicha problemática es el abandono de los conceptos fundacionales de justicia, concausa de la pérdida de estructura y sentido social y estatal

A análise, desde a óptica judia do fenômeno dos linchamentos atuais no marco de uma profunda impunidade e insegurança social, assinala que o motivo dessa problemática é o abandono dos conceitos fundacionais de justiça, com causa da perda de estrutura e do sentido social bem como do Estado

Current lynchings phenomenon seen from the jewish point of view in the context of a deep impunity and social insecurity, indicates that the reason for this problem is the abandonment of the foundational concepts of Justice, concausa's loss of structure and State and social sense

Surgical strategy to repair non-circumferential defect of bile duct in Mirizzi syndrome by own tissues / 中国医师进修杂志

Objective To evaluate the efficacy of surgical repair for non-circumferential defect of bile duct in Mirizzi syndrome.Methods The clinical data of 42 patients with Mirizzi syndrome with non-circumferential defect of bile duct who were repaired using own tissues such as gallbladder pedicle flap,umbilical venous flap and omental flap were analyzed.The defect in the bile duct were repaired using gallbladder pedicle flap in 30 patients,umbilical venous flap in 8 patients and omental flap in 4 patients.Results All patients were operated successfully.There was no operative mortality.There were 2 patients who developed postoperative complications.There was one postoperative bile leakage in a patient who was repaired using an umbilical venous flap.The other complication was residual bile duct stones.The patient with postoperative bile leakage was drained through a drainage tube which was removed after 7 d.The residual bile duct stones were removed by endoscopy through a T-tube sinus after 9 months.All patients were confirmed by T-tube cholangiography after 9-12 months to have no stones,bile duct stenosis or any other abnormalities.The T-tube was then removed.All patients were followed up for 1-5 years,and had no cholangitis,abdominal pain,jaundice or fever.Conclusions Using own tissues such as gallbladder pedicle flap,umbilical venous flap and omental flap to surgical repair the defect in the bile duct of patients with Mirizzi syndrome is effective.This surgical treatment is a good choice.

Las prácticas corporales en la educación corporal / Corporal practices in Corporal Education / Práticas corporais na educação corporal

Este trabajo tiene como propósito abordar la motricidad a partir de prácticas corporales como el danzar, jugar y caminar, así como el gesto y las sensaciones kinestésicas en el horizonte de la Educación Corporal. Interesa mostrar la Motricidad como esa experiencia que nosotros mismos hacemos del cuerpo (leiblich) para establecer una relación con la Educación. La motricidad, en el horizonte de la Educación Corporal, realza las prácticas corporales no con el fin de prescribir prácticas institucionalizadas o normalizadas sino con la pretensión de favorecer experiencias para disponer estados de afección, como ese pathos que sucede ocurriendo, afectando, tocándonos y actuando sobre nosotros, lo cual supone una mirada de la Educación bajo la figura del acontecimiento, que no pretende planificar lo sensible ni normativizar la experiencia.

This work aims to approach the movement based on corporal practices such as dance, play and walk, as well as gesture and kinesthetic sensations on the perspective of Corporal Education. It is interested in showing the movement as the experience that we ourselves make about the corpse (leiblich) to establish a relationship with the Education. Movement, on the perspective of Corporal Education, enhance corporal practices not to prescribe institutionalized or standardized practices, but with the aim of encouraging experiences to provide affection states, like pathos that happens taking place, affecting, touching and acting on us, which assumes a view of Education in the form of the event, which does not intend to plan the sensitive or establishing experience.

Este trabalho tem como objetivo abordar a motricidade a partir de práticas corporais, como dançar, jogar e caminhar, assim como o gesto e as sensações cinestésicas no horizonte da Educação corporal. Interessa mostrar a Motricidade como essa experiência que nós mesmos fazemos do Corpo (leiblich) para estabelecer uma relação com a Educação. A motricidade, no horizonte da Educação Física, realça as práticas corporais não com o fim de prescrever práticas institucionalizadas ou normatizadas, mas com a pretensão de favorecer experiências, e como este pathos ocorre, afetando, tocando-nos e atuando sobre nós mesmos, o que pressupõe examinar a Educação à luz do acontecimento, que não pretende planejar o sensível nem normatizar a experiência.

O nascer do outro na mente: o nascer da própria mente: antes... Agora... E depois? / The birth of the other in one's mind: the birth of one's mind: before... now... and after? / El nacimiento del otro en la mente: el nacimiento de la propia mente: antes... ahora... y despues?

A autora relata uma experiência emocional vivida com sua paciente quando do desenvolvimento da percepção do nascer de sua própria mente e também a experiência sofrida por ela do reconhecimento da existência do outro. Observa um padrão de relacionamento ao longo do trabalho analítico onde a força da manutenção do vínculo na dupla ocorre através da oscilação presença<->ausência abrupta e ameaçadora da paciente, tanto nas sessões como em suas relações. Utiliza vinhetas clínicas como estímulo à compreensão do que se propôs. A autora faz um convite à reflexão a respeito dos desdobramentos dessas descobertas sobre a questão da temporalidade proposta no título do: antes... do agora... e do depois...

The author reports an emotional experience lived with her patient when developing the perception of the birth of her own mind and also the suffering experience of recognizing the existence of the other. It has been observed a relationship pattern throughout the analytic work in which the maintenance strength of the pair link occurs through the oscillation of the abrupt and threatening “presence<->absence” of the patient, either in the sessions or in her relationships with other people. Clinical vignettes are used as a stimulus to understand what is being proposed. The author invites to and suggests a reflection concerning the breakdown of those findings about the temporality matter presented in the title: before… now… and after….

La autora relata una experiencia emocional vivida con su paciente cuando estaba produciéndose el desarrollo de la percepción del nacimiento de su propia mente y también de la experiencia sufrida por ella al reconocer la existencia del otro. Observa un modelo de relacionamiento a lo largo del trabajo analítico donde la fuerza de manutención del vínculo de la dupla ocurre a través de la oscilación presencia-ausencia, abrupta y amenazadora de la paciente, tanto en las sesiones como en sus relacionamientos. Utiliza viñetas clínicas como estímulo a la comprensión de lo que se propone. La autora hace una invitación para reflexionar a respecto de los desdoblamientos de esos descubrimientos sobre la cuestión de la temporalidad propuesta en el título: del antes… del ahora y del después.