Proposal for the Modification of the Method to Evaluate the Midpalatal Suture Maturation Status / Proposta de Modificação do Método para Avaliação do Status da Sutura Palatina Mediana

The objective of present research was to propose a new definition for the midpalatal suture (MPS) maturational stages through reevaluation of intermediate stages B, C and D. The sample was composed by 158 cone-beam computed tomography (CBCT) of individuals between 11 and 20 years of age (±15.4 years, 86 females and 71 males), divided into two groups: 74 individuals aged 11-15 years and 84 individuals aged 16-20 years. The CBCT scans were applied to evaluate midpalatal suture maturation status and comprised stages previously classified as B (29), C (92) and D (37). Each axial image was subdivided into six parts in the anteroposterior direction, and each portion was classified according to MPS maturational evaluation methodology. New definitions of stages were proposed. The reliability of the method was tested by two examiners and the intra- and inter-examiner concordances were defined for each evaluation through weighted kappa coefficients and 95% confidence intervals. The chi-square test was used to compare the groups. In all statistical tests, a significance level of 5% was adopted. Two new maturational stages were defined: sub-stage C- and sub-stage C+, with prevalence of 12% and 8.9%, respectively, in 11 to 20-year-olds. The redefinition and validation of the maturational stages of MPS, considering the sub-stages C- and C+, may allow to elucidate the difference in the prognosis of Rapid Maxillary Expansion among individuals aged 11 to 20 years. This data should be confirmed through a clinical study.(AU)

O objetivo da presente pesquisa foi propor uma nova definição para os estágios maturacionais da sutura palatina média (MPS) por meio da reavaliação dos estágios intermediários B, C e D. A amostra foi composta por 158 tomografias computadorizadas de feixe cônico (TCFC) de indivíduos entre 11 e 20 anos de idade (±15,4 anos, 86 do sexo feminino e 71 do sexo masculino), divididos em dois grupos: 74 indivíduos de 11 a 15 anos e 84 indivíduos de 16 a 20 anos. Os exames de TCFC foram aplicados para avaliar o estado de maturação da sutura palatina média e compreenderam os estágios previamente classificados como B (29), C (92) e D (37). Cada imagem axial foi subdividida em seis partes no sentido anteroposterior, e cada porção foi classificada de acordo com a metodologia de avaliação maturacional MPS. Novas definições de estágios foram propostas. A confiabilidade do método foi testada por dois examinadores e as concordâncias intra e interexaminadores foram definidas para cada avaliação por meio de coeficientes kappa ponderados e intervalos de confiança de 95%. O teste do qui-quadrado foi utilizado para comparar os grupos. Em todos os testes estatísticos adotou-se o nível de significância de 5%. Dois novos estágios maturacionais foram definidos: subestágio C- e subestágio C+, com prevalência de 12% e 8,9%, respectivamente, em jovens de 11 a 20 anos. A redefinição e validação dos estágios maturacionais da MPS, considerando os subestágios C- e C+, podem permitir elucidar a diferença no prognóstico da Expansão Rápida da Maxila entre indivíduos de 11 a 20 anos. Esses dados devem ser confirmados por meio de um estudo clínico.(AU)

Tonsilolito gigante: hallazgo inesperado. Reporte de caso / Giant tonsillolith: unexpected finding. Case report

Introducción: se presenta el caso de un tonsilolito gigante periamigdalino como hallazgo en una radiografía panorámica de rutina en odontología. Caso clínico: se presenta el caso de un paciente masculino de 26 años a quien le realizaron radiografía panorámica de control, en la que se evidenció una gran imagen radiopaca a nivel periamigdalino derecho de aproximadamente 2 cm de diámetro; el paciente fue asintomático al momento de la consulta y al recibir tratamiento quirúrgico se evidenció un tonsilolito gigante que fue retirado en bloque sin complicaciones. Discusión: se presentan diagnósticos diferenciales de imágenes radiopacas encontradas en radiografías de cabeza y cuello compatibles con tonsilolitos. Conclusiones: se recuerda esta entidad diagnóstica que, aunque rara, se debe tener presente como posible hallazgo en estudios de imagen cabeza y cuello o síntomas a nivel amigdalino.

Introduction: We present the case of a giant tonsil stone as a finding in routine pano-ramic radiography in dentistry. Clinical case: we present the case of a 26 years-old male patient who underwent a control panoramic radiography where a large radiopa-que image of approximately 2 cm in diameter was evidenced at the right peritonsillar level; the patient was asymptomatic at the time of the consultation, when recei-ving surgical treatment, a giant tonsillolith was evidenced which was removed en bloc without complications. Discussion: differential diagnosis of radiopaque ima-ges found in head and neck radiographs compatible with tonsilloliths are presented. Conclusions: Although rare, this entity should be kept in mind as a possible finding in head and neck imaging studies or symptoms at tonsillar space.

Is there a relationship between tonsil volume and the success of pharyngeal surgery among adult patients with obstructive sleep apnea?

Abstract Objectives: Hypertrophic palatine tonsils play a role in the blockage of the upper airway, one of the known causes of Obstructive Sleep Apnea (OSA). Therefore, it is possible that there is an association between tonsil size and the success of pharyngeal surgery during OSA treatment. The main objective of this study was to evaluate the relationship between tonsil grade and volume, as well as to establish whether a relationship exists between tonsil size and the success rate of pharyngeal surgery (tonsillectomy and pharyngoplasty with barbed sutures). Methods: This retrospective study includes forty-four adult patients who underwent tonsillectomy and pharyngeal surgery with barbed sutures for the treatment of simple snoring and OSA between January 2016 and September 2019. Patients who had been previously tonsillectomized or those for whom tonsil volume measurement was lacking were excluded. All patients underwent a pre-operative physical exploration at the clinic exam room and a sleep study. Prior to surgery a Drug Induced Sleep Endoscopy (DISE) was performed. Tonsil volume was measured intraoperatively using the water displacement method. The same sleep study was repeated six months following surgery. Results: A significant correlation was found between tonsil grade and volume and between such measurements and the blockage observed at the level of the oropharynx during the DISE. Moreover, an association was observed between tonsil volume, but not tonsil grade, and the success of tonsillectomy and pharyngoplasty with barbed sutures. A tonsil volume greater than 6.5 cm3 was linked to success during pharyngeal surgery. Conclusion: A correlation exists between tonsil grade and tonsil volume. A bigger tonsil volume is associated with a greater success rate of oropharyngeal surgery during treatment of OSA. Level of evidence: Level 3, non-randomized cohort study.

The pterygopalatine ganglion, palatine nerves and vessels: dissection and pathway / El ganglio pterigopalatino, nervios palatinos y vasos: disección y trayecto

SUMMARY: Background and Objectives: The palatine nerves and vessels cross the pterygopalatine fossa, the palatine canals, the palatine foramina and the submucosal space, at the level of the hard palate and the palatine recess of the maxillary sinus. Their trajectory is long, complicated and difficult to highlight on a single dissection piece. In the literature that we studied, we did not find clear images that fully highlight the real configuration of the pterygopalatine ganglion and nerves and of the palatine vessels. Our aim was to provide a clear and representative dissection of the pterygopalatine ganglion and of the palatine neurovascular bundle throughout its pathway in a simple, coherent and useful presentation for the practitioners interested in the regional pathology. We resected the posterior and inferomedial osseous walls of the maxillary sinus and highlighted the neurovascular structures in the pterygopalatine fossa and the wall of the maxillary sinus. We photographed the dissection fields and detailed the important relations. The images that we obtained are clear, simple and easy to interpret and use. We successfully highlighted the aspect and the main relations of the pterygopalatine ganglion and the pathway and distribution of the palatine nerves and vessels, from their origin to the terminal plexuses. There is a broad spectrum of clinical procedures or situations that require a proper knowledge and understanding of the anatomical pathway and relations of the palatine neurovascular elements. This includes the various types of regional anesthesia, tumor resection surgery, flaps of the palatine mucosa, the LeFort osteotomy etc. Demonstration of the pterygopalatine ganglion and its relations is useful in endoscopic interventions at the level of the pterygopalatine fossa.

RESUMEN: Los nervios y vasos palatinos atraviesan la fosa pterigopalatina, además de los canales palatinos, los forámenes palatinos y el espacio submucoso a nivel del paladar duro y el receso palatino del seno maxilar. Su trayectoria es larga, complicada y difícil de destacar en una sola pieza de disección. En la literatura que estudiamos, no encontramos imágenes claras que resalten completamente la configuración real del ganglio y los nervios pterigopalatinos y de los vasos palatinos. Nuestro objetivo fue proporcionar una disección clara y representativa del ganglio pterigopalatino y del haz neurovascular palatino a lo largo de su trayecto en una presentación simple, coherente y útil para los médicos interesados en la patología regional. Resecamos las paredes óseas posterior e inferomedial del seno maxilar y resaltamos las estructuras neurovasculares en la fosa pterigopalatina y la pared del seno maxilar. Fotografiamos los campos de disección y detallamos las relaciones importantes. Las imágenes que obtuvimos son claras, sencillas y de fácil interpretación. Resaltamos con éxito el aspecto y las principales relaciones del ganglio pterigopalatino y el trayecto y distribución de los nervios y vasos palatinos, desde su origen hasta los plexos terminales. En conclusion, existe un amplio espectro de procedimientos o situaciones clínicas que requieren un adecuado conocimiento y comprensión del trayecto anatómico y las relaciones de los elementos neurovasculares palatinos. Esto incluye los distintos tipos de anestesia regional, cirugía de resección tumoral, colgajos de mucosa palatina, osteotomía de LeFort, etc. La demostración del ganglio pterigopalatino y sus relaciones es útil en intervenciones endoscópicas a nivel de la fosa pterigopalatina.

CBCT study on the safe location of palatal microscrew implant anchorage nail between maxillary first and second molars / 口腔疾病防治

Objective@#Conebeam CT (CBCT) was used to measure the palatine between the maxillary first and second molars. The proximal and distal palatal widths of the maxillary first and second molar and the palatal mucosal thickness and bone tissue thickness when microscrew implant anchorage nail were implanted at different angles provided a reference for the clinical selection of microscrew implant placement.@* Methods@#The image data of 90 adult patients were selected as the research object, and the jaw bone was reconstructed by scanning. In maxillary palatine, selection of distances at 12 mm, 14 mm, 16 mm, and 18 mm from the palatal apex of maxillary first molar between the maxillary first and second molar were used as measurement, measured the proximal and distal palatal widths of maxillary first and second molar and the palatal mucosal thickness and bone tissue thickness when microscrew implant anchorage nails were implanted at 30 °, 45 °, 60 °, and 90 °. SPSS 26.0 software was used for one-way ANOVA and LSD pair comparison. @*Results@#The larger the angle of the microscrew implant anchorage nail was, the smaller the proximal and distal medial widths between the maxillary first and second molar, and the difference was statistically significant (P < 0.05). Compared with the 90° direction, the proximal and distal medial widths of the microscrew implant anchorage nail were larger in the 60° direction. The greater the angle of implantation, the smaller the mucosal thickness and the greater the bone tissue thickness, and the results showed a significant difference (P < 0.001). Compared with the direction of 30° and 45°, the mucosal thickness at the direction of 60° was smaller, and the bone tissue thickness was larger. The higher the position of the microscrew implant anchorage nail, the greater the width of the proximal and distal medial, and the difference was statistically significant (P < 0.05). Compared with the positions 12 and 14 mm from the palatal tip, the proximal and distal medial widths of the microscrew implant anchorage nail were larger. The higher the implant position was, the greater the mucosal thickness and the smaller the bone tissue thickness. The results showed a significant difference (P < 0.001). Compared with the position of 18 mm from the palatal tip of the maxillary first molar, the mucosal thickness was smaller and the bone tissue thickness was larger.@*Conclusion@#It is most appropriate to implant microscrew implant anchorage nail at least 10 mm in length in the direction of 60° at the palatal apex 16 mm from the maxillary first molar in palatine between the first and second molar.

Prevalence of epstein-barr virus infection in palatine tonsils hyperplasia through the immunoexpression of the LMP-1 marker / Avaliação da prevalência de infecção por epstein-barr vírus na hiperplasia de tonsilas palatinas através da imunoexpressão do marcador LMP-1

Introduction: LMP-1 (latent membrane protein 1) is a membrane protein found in EBV and can be identified through immunohistochemistry. Objectives: To evaluate the prevalence of EBV virus in tonsillar tissue samples correlating with tonsil size, age and gender. Methods: An LMP-1 immunohistochemical study was performed in slides from patients with tonsil hyperplasia. Results: The sample consisted of 120 slides, 66 were from male. The average tonsillar size was 6.0 cm2 (1.5-14.0) and the average age was 6.5 years (2-18). Overall, 72 patients were positive for the virus, the majority being male (51%) and preschoolers (51.4%). For comparative analysis, the sample was divided: group 1 (positive immunohistochemistry) and group 2 (negative immunohistochemistry). The average age was 6.74 years (± 4.14) and 6.19 years (± 3.82) for group 1 and 2, respectively. Group 1 had 37 preschoolers, 23 school-age children and 12 adolescents. Group 2 had 28 preschoolers, 14 school-age children and 6 adolescents (p=0.71). To evaluate the presence of virus, the slides were divided according to area: G (≥6cm²) and P (<6cm²). In G group, 54 slides were positive, while in P group, 18 were positive. Group 1 presented 54 of G group slides and 18 of P group slides, with no statistical difference, but with a tendency to positivity (p=0.09). Conclusion: Most of the sample was positive for the presence of Epstein-Barr virus. There was no difference in the virus presence or absence when correlated with the tonsillar size, age or sex

Introdução: LMP-1 (proteína latente de membrana-1) é uma proteína de membrana encontrada no Epstein-Barr vírus (EBV) e que pode ser identificadaatravés da imunoistoquímica. Objetivo: Avaliar a prevalência do EBV em amostras de tecido tonsilar correlacionando com o tamanho da tonsila, idade e sexo. Método: Realizou-se um estudo imunoistoquímico de LMP-1 para EBV em lâminas de pacientes com hiperplasia de tonsilas. Resultados: A amostra foi composta por 120 lâminas, sendo 66 (55%) de pacientes do sexo masculino. O tamanho médio tonsilar foi 6,0 cm2 (1,5-14,0) e a idade média 6,5 anos (2-18). Ao todo, 72 pacientes (60%) tiveram positividade para o vírus, a maioria meninos (51%) e pré-escolares (51,4%). A amostra foi dividida em: grupo 1 (imunoistoquímica positiva) e grupo 2 (imunoistoquímica negativa). A idade média foi de 6,74 anos (±4,14) e 6,19 anos (±3,82), para o grupo 1 e 2, respectivamente. O grupo 1 apresentou 37 pré-escolares, 23 escolares e 12 adolescentes. O grupo 2 foi composto por 28 pré-escolares, 14 escolares e 6 adolescentes, sem diferença estatística (p=0,71). Para avaliar a presença do EBV, as lâminas foram divididas de acordo com a área: G (≥6 cm²) e P (<6 cm²). No grupo G, 54 lâminas foram positivas, enquanto no grupo P, 18, sem diferença estatística, mas com tendência a positividade (p=0,09). Conclusão: A maior parte da amostra foi positiva para o Epstein-Barr vírus. Não houve diferença significante na positividade ou não do vírus quando correlacionada com o tamanho tonsilar, a idade e o sexo dos pacientes.

Pólipos linfangiomatosos de las amígdalas palatinas en la infancia: Reporte de un caso y revisión / Lymphangiomatous polyps of the palatine tonsils in childhood: A case report and review

Introducción: Los pólipos linfangiomatosos de las amígdalas palatinas son lesiones benignas raras. Esta entidad se origina en el estroma linfoide mezclándose con el parénquima, siendo diferente a la hiperplasia papilar y representa aproximadamente el 1,9% de las neoplasias de amígdalas. Objetivo: Presentar un caso clínico y una búsqueda sistemática de los casos pediátricos publicados en la literatura. Reporte de caso: se ha realizado una revisión sistemática siguiendo las pautas PRISMA de los reportes en PubMed, Elsevier, Google Académico de 2010 a 2021. Se localizaron 18 artículos en los que se encontró 8 mujeres y 10 hombres, la edad promedio fue de 14 años, en 15 las lesiones eran unilaterales. Todos los casos reportaron en los hallazgos histopatológicos la presencia de vasos linfáticos. Conclusión: Existe variabilidad entre la edad con distribución similar entre sexos; al ser una entidad infrecuente hay heterogeneidad en su denominación.

Background: Lymphangiomatous polyps of the palatine tonsils are rare benign lesions. This entity originates from the lymphoid stroma intermixed with parenchyma, being different from papillary hyperplasia, representing approximately 1.9% of tonsillar neoplasms. Objective: To present a case report and systematic review of the pediatric cases published in the literature. The report case: A systematic review was carried out following the PRISMA guidelines of the reports in PubMed, Elsevier, Google Scholar from 2010 to 2021. 18 articles were found of which 8 females and 10 males were found, the mean age was 14 years, in 15 lesions were unilateral. All cases reported the presence of lymphatic vessels in the histopathological exam. Conclusion: There is variability with age with a similar distribution between genders, being rare there is heterogeneity in its denomination.

Asymmetric palatine tonsil in a pediatric patient: Is it always a malignant neoplasm? / Asimetría amigdalina en pediatría: ¿cuándo sospechar malignidad?

Abstract Background: A relatively frequent clinical finding in children is an asymmetric tonsil, which can have multiple etiological possibilities, including a malignant disease. The clinical finding of tonsillar asymmetry is found in approximately 2% of the pediatric population. The incidence of malignancy in the tonsils is low, estimated as 2.5 cases per 10,000 tonsillectomies. Due to its low incidence, the diagnostic tonsillectomy is not justified when tonsillar asymmetry is the only clinical finding. However, it is necessary to identify the critical clinical findings of high suspicion of malignancy that justify the performance of immediate surgery in the pediatric population. Case report: We present the case of a 10-year-old male patient. Four months before admission, the patient started with pharyngodynia and dysphagia, treated as recurrent tonsillitis. Due to exacerbation of the symptoms, orthopnea, and B symptoms, the patient came to consultation; tonsillar asymmetry was observed predominantly on the left side, with exophytic lesions extending to the hypopharynx. We decided to perform an incisional biopsy and tracheostomy due to compromised airway; histopathological diagnosis came back as B-cell lymphoma. Conclusions: Given the clinical scenario of recurrent tonsillitis, unresponsive to conventional medical treatment with antibiotics, tonsillar asymmetry with suspicious tonsillar appearance accompanied by symptoms such as fever, diaphoresis, cervical lymphadenopathy, obstructive symptoms in a pediatric patient, it is necessary to refer the patient to the specialist for timely diagnosis and treatment.

Resumen Introducción: La asimetría amigdalina es un hallazgo clínico relativamente frecuente en los niños. Se ha reportado en el 2% de la población pediátrica e incluye múltiples etiologías, entre ellas enfermedad maligna. La incidencia de malignidad es baja: se estima en 2.5 casos por cada 10,000 amigdalectomías. Por tal motivo, cuando se observa asimetría amigdalina como único hallazgo en la exploración física no se justifica la amigdalectomía con fines diagnósticos. Sin embargo, la incertidumbre de malignidad en el médico y en el paciente obliga a considerar los datos clínicos que permitan sospecharla y justificar la intervención quirúrgica. Caso clínico: Se presenta el caso de un paciente de sexo masculino de 10 años. Inició su padecimiento 4 meses previos a su ingreso hospitalario con faringodinia y disfagia, que fueron diagnosticadas y tratadas como amigdalitis recurrente. Acudió al hospital por agudización de los síntomas, evolucionando con ortopnea y síntomas B. En la exploración física se apreció asimetría amigdalina con aumento de volumen en la amígala izquierda extendida hasta la hipofaringe. Se decidió realizar una biopsia incisional y traqueostomía por compromiso respiratorio. El diagnóstico histopatológico fue linfoma de células B. Conclusiones: Ante un paciente pediátrico con amigdalitis recurrente, que no cede al tratamiento médico convencional y presenta asimetría amigdalina con aspecto sospechoso, acompañada de síntomas como fiebre, diaforesis, adenopatías cervicales y síntomas obstructivos, se deberá referir con el especialista para su diagnóstico y tratamiento oportunos.

Morphometric study of incisive, greater and lesser palatine foramina: a novel point of maxillary nerve block in a Thai population / Estudio morfométrico del foramen palatino incisivo, mayor y menor: un punto novedoso de bloqueo del nervio maxilar en una población tailandesa

SUMMARY: To study the morphometric location of the incisive, greater, and lesser palatine foramina for maxillary nerve block. Two hundred Thai dry skulls were randomly organized from the Forensic Osteology Research Center. The distances of the parameters were measured via Vernier caliper.: Thedistances from the incisive foramen to the incisive margin of the premaxilla were 10.93?2.42 mm in males and 10.98?2.06 mm in females. From the left side, the incisive foramen to the greater palatine foramen (GPF) was39.07?2.23mm in males and 38.57?2.41 mm in females, and from the right side were 39.81?2.37 mm in males and 38.62?2.53mm in females. From the left side, the incisive foramen to the lesser palatine foramen (LPF) was 43.16?2.23 mm in males and 41.84?2.42mm in females and from the right side were 42.93?2.14 mm in males and 41.76?2.61 mm in females. The GPF found at medial to the maxillary third molar were 94-95 % in males and 84 % in females. These findings suggest that the medial position to the third molar teeth be used as a landmark for a palatine nerve block in Thais. These findings will help dentists to perform local anesthetic procedures, especially the nasopalatine and greater palatine nerve blocks, more effectively.

RESUMEN: El objetivo de este trabajo fue estudiar la localización morfométrica de los forámenes palatinos incisivos, mayores y menores para el bloqueo del nervio maxilar. Se organizaron al azar doscientos cráneos secos tailandeses del Centro de Investigación de Osteología Forense. Las distancias de los parámetros se midieron mediante un calibre Vernier. Las distancias desde el foramen incisivo hasta el margen incisivo de la premaxila fueron 10,93 ? 2,42 mm en hombres y 10,98 ? 2,06 mm en mujeres. Desde el lado izquierdo, el foramen incisivo al foramen palatino mayor (FPM) fue de 39,07 ? 2,23 mm en los hombres y 38,57 ? 2,41 mm en las mujeres, y del lado derecho fue de 39,81 ? 2,37 mm en los hombres y 38,62 ? 2,53 mm en las mujeres. Del lado izquierdo, el foramen incisivo al foramen palatino menor (LPF) fue de 43,16 ? 2,23 mm en hombres y 41,84 ? 2,42 mm en mujeres y del lado derecho 42,93 ? 2,14 mm en hombres y 41,76 ? 2,61 mm en mujeres. El FPM encontrado medial al tercer molar maxilar fue 94-95 % en hombres y 84 % en mujeres. Estos hallazgos sugieren que la posición medial de los terceros molares se utilice como punto de referencia para un bloqueo del nervio palatino en individuos tailandeses. Estos hallazgos ayudarán, de manera más eficaz, a los dentistas a realizar procedimientos anestésicos locales, especialmente los bloqueos nasopalatinos y del nervio palatino mayor.

Clinical study of age-related sensory innervation of the anterior hard palate / 华西口腔医学杂志

OBJECTIVES@#The present study aimed to explore the innervation of the anterior hard palatine and its relationship with individual development stage. Specifically, the effects of anesthesia on patients of different ages were observed, and neurodevelopment in the maxillofacial region was invesitgated. References that are helpful in selecting local anesthesia were provided.@*METHODS@#A total of 182 patients with mixed dentition were randomly divided into the nasopalatine nerve block and greater palatine nerve block groups. Then, 219 patients with permanent dentition were divided into an adolescent group (13-18 years old) and adult group (over 19 years old), all of whom underwent bilateral greater palatine nerve block. Palatal mucosal pain sensation was tested pre- and post-anesthesia with Von Frey hairs.@*RESULTS@#Among the children with mixed dentition, bilateral greater palatine nerve block tended to result in better anesthetic effects than nasopalatine nerve block (@*CONCLUSIONS@#The sensation of the anterior hard palatine seems mainly dominated by the greater palatine nerve until mixed dentition and gradually shifted to the nasopalatine nerve in conjunction with maxillary development and tooth replacement. Hence, the innervation of the anterior hard palatine induce a secondary development during the development of the maxilla.

Prevalence of soft tissue calcifications in CBCT images from the oral and maxillofacial radiology service at UNAB, Viña del Mar, Chile / Prevalencia de calcificaciones en tejidos blandos en CBCT del servicio de radiología oral y maxilofacial de la UNAB sede Viña del Mar, Chile

Soft tissue calcifications can indicate the presence of more serious, potentially life-threatening pathologies. Therefore, their study can lead to an early diagnosis of those conditions that have not yet become clinically apparent. Main objective: To determine the prevalence of calcifications in soft tissues of the head and neck in cone beam computed tomography images obtained from the Oral and Maxillofacial Radiology Service at Universidad Andrés Bello (UNAB), Viña del Mar, Chile. Material and Methods: Retrospective, cross-sectional, quantitative study. A total of 288 images of cone beam computed tomography (CBCT) were used. Images were obtained at random from the database of the Oral and Maxillofacial Radiology Service at UNAB, Viña Del Mar, between 2014 and 2019. Results: A prevalence of 59.72% of soft tissue calcifications was obtained. The most prevalent were: tonsilloliths and calcified stylohyoid ligament, accounting for 30.65% and 45.56%, respectively. Conclusion: A high prevalence of soft tissue calcifications was found in a population that has not been studied previously; therefore, it is important that the dentist perform a detailed analysis of the cone beam computed tomography.

Introducción: Las calcificaciones en tejidos blandos pueden indicar patologías más graves, que incluso pueden comprometer la vida. Por lo tanto, investigarlas puede conducir a un diagnóstico temprano de aquellas que aún no se han manifestado clínicamente. Objetivo principal: determinar la prevalencia de calcificaciones en tejidos blandos de cabeza y cuello en tomografía computarizada de haz cónico del Servicio de Radiología Oral y Maxilofacial de la UNAB, Viña del Mar, Chile. Material y Métodos: Estudio retrospectivo, transversal, cuantitativo. Se utilizaron 288 volúmenes de tomografía computarizada de haz cónico (CBCT, por las iniciales en inglés de Cone Beam Computed Tomography), obtenidas al azar, de la base de datos del Servicio de Radiología Oral y Maxilofacial de la Universidad Andrés Bello (UNAB), Viña del Mar entre 2014 y 2019. Resultados: Se obtuvo una prevalencia de 59.72% de calcificaciones en tejidos blandos. Las más prevalentes fueron: tonsilolitos, con un 30,65% y ligamento estilohioídeo calcificado, con un 45,56%. Conclusión: Se encontró una alta prevalencia de calcificaciones en tejidos blandos en una población que no ha sido estudiada previamente, por ello es importante que el odontólogo realice un análisis detallado de la tomografía computarizada de haz cónico.

Influence of the palatine tonsil grade on the morphology of the maxillary and mandibular dental arches / Influencia del grado de las tonsilas palatinas en la morfología de los arcos dentales maxilar y mandibular

SUMMARY: Enlarged palatine tonsils and adenoids are thought to cause obstruction of the upper airway, triggering changes in breathing patterns, which in turn lead to dentofacial alterations, including malocclusions. The object of the present study was to correlate the size (grade) of the palatine tonsil with measurements of the maxillary and mandibular dental arches in children. This was an observational cross-sectional study carried out in 35 children aged between 6 and 11 years. The inter- and intra-arch parameters were measured (horizontal, vertical and sagittal analyses) by making plastercasts and then taking measurements with callipers. The tonsil size was classified in 5 grades from 0-4, using the Brodsky tonsil grading scale. The researcher was calibrated prior to carrying out the measurements. Pearson's chi-squared test was used and Pearson's correlation coefficient was calculated. The SPSS v.22.0 software was used, with a significance threshold of 5 %. Six patients were classified as grade 1, sixteen grade 2, eleven grade 3, two grade 4 and none of the patients presented grade 0.A low positive association was found between tonsil grade and the total length of the mandibular arch, a very low positive association between tonsil grade and maxillary inter-first premolar distance, total length of the maxillary arch and depth of the palatine recess.A very low negative association was found for tonsil grade and overjet, overbite, mandibular inter-permanent first molar distance, mandibular inter-first premolar distance, and mandibular and maxillary intercanine widths. No statistically significant correlation was observed for any of the measurements. No association was found between the tonsil grade and Angle's Classification, canine relationship, overjet and overbite. According to the results of this study there is no significant correlation between the dental arches and the tonsil grade.

RESUMEN: Se ha considerado que el grado del tamaño de las tonsilas palatinas y los adenoides pueden ser factores que generan obstrucción de la vía aérea superior, desencadenando cambios en el patrón de respiración, lo que provoca alteraciones dentofaciales, entre ellas, maloclusiones. El objetivo del presente estudio fue correlacionar el grado tonsilar palatino con medidas de los arcos dentales maxilar y mandibular en niños. Se realizó un estudio observacional de corte transversal. Fueron incluidos 35 niños entre 6 y 11 años de edad. Fueron medidos parámetros interarco e intra-arco (análisis transversal, vertical, sagital). Para eso fueron tomados modelos de yeso y luego las medidas fueron realizadas con un caliper. El grado tonsilar fue clasificado en 5 grados (0-5), de acuerdo a la escala de graduación de Brodsky. Para la realización de las mediciones el evaluador fue previamente calibrado. Se realizó la prueba Chi-cuadrado de Pearson, y coefi- ciente de correlación de Pearson. Se utilizó el software SPSS 22.0, considerándose umbral de significación de 5 %. Seis pacientes fueron clasificados en grado 1, dieciséis grado 2, once grado 3, dos grado 4 y ningún paciente presentó grado 0. Se encontró una asociación positiva baja entre grado tonsilar y la longitud total del arco mandibular, positiva muy baja entre grado tonsilar y distancia inter-primer premolar maxilar, longitud total del arco maxilar y profundidad de la bóveda palatina. Una asociación negativa muy baja fue encontrada para el grado tonsilar y overjet, overbite, distancia inter-primer molar permanente mandibular, distancia inter- primer premolar mandibular, ancho intercanino mandibular y maxilar. Se observó ausencia de correlación estadísticamente significativa para todas las medidas. No se encontró asociación entre el grado tonsilar y clase molar de Angle, relación canina, overjet y overbite. Según los resultados de este estudio no se aprecia una correlación significativa entre los arcos dentales y el grado tonsilar.

Comparison of Greater Palatine Nerve Block with Intravenous Fentanyl for Postoperative Analgesia Following Palatoplasty in Children

Good pain relief after palatoplasty is important as inadequate analgesia with vigorous cry leads to wound dehiscence, removal of sutures and extra nursing care. Decrease in oxygen requirement and cardio-respiratory demand occur with good pain relief and also promotes early recovery. Preoperative opioids have concerns like sedation, respiratory depression and airway compromise. Greater palatine nerve block with bupivacaine is safe and effective without the risk of respiratory depression. The study was done to compare pain relief postoperatively with intravenous fentanyl and greater palatine nerve block in children following palatoplasty. Methods80 children of ASA I & II, between 1 to 7 years were included and allocated into two groups of 40 each. Analgesic medication was given preoperatively after induction of general anaesthesia, children in Group B received greater palatine nerve block with 2 mL 0.25% inj. Bupivacaine (1 mL on each side) and Group F received 2 μg Kg-1 I.V. fentanyl as 2 mL solution. Assessment of pain was done by FLACC scale and recovery profile by Modified Aldrete Score. Haemodynamic monitoring along with side effects was assessed. Data was analysed using SPSS software (Statistical Package of Social Science) version 17.0. p-value of < 0.05 was considered significant. ResultsPatients receiving block showed significantly better recovery profile (9.22 ± 0.39) vs (8.78 ± 0.61), duration of analgesia (482.59 +93.76) vs (174.13 +84.91) and less mean paracetamol consumption (126.66 +18.70) vs (151.79 +60.03) with comparable haemodynamics and side effects. ConclusionsGreater palatine nerve block provides effective postoperative pain relief after palatoplasty in children compared to I.V. fentanyl. It is safe, easy to perform, and free of complications.

Inflammatory markers in palatine tonsils of children with obstructive sleep apnea syndrome / Marcadores inflamatórios em tonsilas palatinas de crianças com síndrome da apneia obstrutiva do sono

Abstract Introduction Obstrutive sleep apnea syndrome is characterized by repeated episodes of upper airway obstruction, associated with intermittent hypoxia and hypercapnia, and the main risk factor in childhood is adenotonsillar hypertrophy. The lymphocytes in these structures are responsible for local and systemic immune responses. Objective Verify the levels of the inflammatory markers, IL-1β, IL-4, IL-6, IL-8, IL-10, IL-15, TNF-α, CRP and α1-GP, in the tonsils of children with and without obstructive sleep apnea syndrome. Methods This cross-sectional prospective study included 34 children with complains of snoring, difficulty breathing during sleep or recurrent tonsillitis. Patients underwent to a complete otorhinolaryngological examination, nasal endoscopy and polysomnography and were divided into two groups with 17 children each: obstructive sleep apnea syndrome group and control group. All underwent an adenotonsillectomy. Cytokines were measured in the collected tonsils (ELISA and Multiplex methods). Results Statistically significant increasing were observed between IL-8 and IL-10 cytokines of patients with obstructive sleep apnea when compared to the control group; also between c-reactive protein and α1-GP of the tonsils cortical region in children with obstructive sleep apnea syndrome when compared with the medullary region. There were no statistically significant differences for the remaining inflammatory mediators. Conclusion After the analysis of the levels of pro and anti-inflammatory markers (IL-1β, IL-4, IL-6, IL-8, IL-10, Il-15, TNF-α, CRP, α1-GP) in the tonsils, we observed higher levels of markers IL-8 and IL-10 in pediatric patients with obstructive sleep apnea syndrome.

Resumo Introdução A síndrome da apneia obstrutiva do sono é caracterizada por episódios repetidos de obstrução das vias aéreas superiores, associados a hipóxia intermitente e hipercapnia, e o principal fator de risco na infância é a hipertrofia adenotonsilar. Os linfócitos nessas estruturas são responsáveis por respostas imunes locais e sistêmicas. Objetivo Dosar os marcadores inflamatórios, IL-1β, IL-4, IL-6, IL-8, IL-10, IL-15, TNF-α, PCR e α1-GP, nas tonsilas de crianças com e sem síndrome da apneia obstrutiva do sono. Método Estudamos prospectivamente 34 crianças que se queixavam de ronco, dificuldade para respirar durante o sono ou tonsilites recorrentes. Os pacientes foram submetidos a exame otorrinolaringológico completo, endoscopia nasal e polissonografia e foram divididos em dois grupos com 17 crianças cada: síndrome de apneia obstrutiva do sono e controle. Todos foram submetidos à adenotonsilectomia. As citocinas foram medidas nas tonsilas coletadas (métodos ELISA e Multiplex). Resultados Com diferenças estatisticamente significantes, observou-se aumento das citocinas IL-8 e IL-10 em pacientes com apneia obstrutiva do sono em comparação ao grupo controle, assim como aumento dos níveis de proteína C reativa e de α1-GP na região cortical das tonsilas de crianças portadoras de síndrome da apneia obstrutiva do sono em comparação com a região medular. Não houve diferenças estatisticamente significantes para o restante dos mediadores inflamatórios. Conclusão Após a análise dos níveis de marcadores pró e anti-inflamatórios (IL-1β, IL-4, IL-6, IL-8, IL-10, Il-15, TNF-α, PCR, α1-GP) nas tonsilas, observamos níveis mais altos de marcadores IL-8 e IL-10 em pacientes pediátricos com síndrome da apneia obstrutiva do sono.

Hipertrofia de amígdalas linguales: presentación de casos revisión narrativa / Lingual tonsil hypertrophy: presentation of cases narrative review

Actualmente no es sólito tener pacientes con síntomas causados por la implicación de las amígdalas linguales y que pasemos por alto su sospecha. Los signos y síntomas que pueden presentar los pacientes son variados, desde el síndrome de apnea obstructiva del sueño (síntoma más común) y disfagia hasta tos crónica mal abordada y, por lo mismo, tratada inadecuadamente. Presentamos los casos clínicos de dos pacientes con hipertrofia de amígdalas linguales y una revisión narrativa del tema.

Currently, it is not unusual to have patients with symptoms due to the involvement of lingual tonsils and let us go unnoticed their suspicion. The signs and symptoms that patients may present are varied, from giving obstructive sleep apnea syndrome (the most common symptom) dysphagia to poorly treated and poorly treated chronic cough. We present the clinical cases of two patients with hypertrophy of the lingual tonsils and a narrative review of the subject.

Anatomical Study On Location Of Greater Palatine Foramen In Dried Adult Human Skull: Key To Successful Maxillary Nerve Block

Background: The greater palatine foramen (GPF) conducts greater palatine nerve, responsible for the innervationof posterior part of the hard palate. Anaesthetic block for greater palatine nerve is highly recommended forsurgical practices involving upper molar, maxillary sinus and nasal region. But the practical problem associatedwith anaesthesia is difficulty in locating the exact position of greater palatine foramen, leading to deliveringinsufficient anaesthetic solution. The greater palatine neurovascular structures enter the oral cavity through thegreater palatine foramen so this foramen should be approached carefully during any surgical procedures toavoid damage to these neurovascular structure.Materials and methods: 126 dried adult skull bones of unknown sex, obtained from the department of anatomy,MVJ Medical College and Research Hospital were used to locate the exact position of greater palatine foramen inrelation to bony landmarks. On both side, the distance of greater palatine foramen from midline maxillarysuture, posterior border of hardpalate, incisive fossa and lesser palatine foramen were measured with digitalvernier caliper. Location of GPF in relation to molar or premolar tooth was also noted. The data obtained wereanalyzed statistically by calculating mean and standard deviation. The percentage was calculated for the locationof GPF in relation to molar or premolar tooth.Result: In the present study of anthropometric analysis of greater palatine foramen of 126 dried skulls, it wasobserved that the most common location of greater palatine foramen was opposite to the third molar tooth. Themean distance between greater palatine foramen to mid maxillary suture was 13.71mm on right side and13.72mm on left side and posterior border of hard palate on right side was 4.62mm and 4.49mm on left side. Themean distance between greater palatine foramen and incisive fossa was 36.73mm and 36.66mm on the right andleft side respectively. The mean distance between greater palatine foramen and lesser palatine foramen was1.47mm on right side and 1.49 mm on left side.Conclusion: Results of present study may contribute greatly to the successful outcome of maxillofacial and oralsurgeries regional anaesthesia.

A Study Of Palatal Indices And Foramina In The Hard Palate Of Adult Human Skulls In Central India Region

Aim of study: Aim of study: The aim of the study is to determine morphometric indices of hard palate, positionand location of greater palatine foramen (GPF) in relation to maxillary molars and number of lesser palatineforamen (LPF).Materials and methods: 100 adult skulls (65 males and 35 females) were obtained from the Department ofAnatomy. The parameters of hard palate like length, breadth and height were measured and palatine indiceswere calculated. Observations were made on the position and relation of GPF with maxillary molar and numberof LPF. There were highly significant differences between both the sexes in Palatal length, breadth and height. Thepalatine index indicated that majority (61%)of skulls had narrow palate (Leptostaphyline).The palatine heightindex showed that majority (69%) of skulls had high arched or deep palate.(Hypsistaphyline). The greater palatineforamen was at the level of third molar in 50%, in between second and third molar in 35.5%, and at the level ofsecond molar in 14% . In majority of skulls (71%) one lesser palatine foramen was observed and about (35%) ofskulls had two LPF and (2.5%) of skulls had three LPF, and in about (5.5%) absence of LPF was observed.Conclusion: Thorough anatomical study of hard palate is useful in ethnic and racial classification of crania,anthropological studies, fabricating complete maxillary dentures for edentulous patients and performing certainsurgical procedures in hard palate and soft palate. Knowledge of palatal indices would be helpful to the anatomists,anthropologists, and forensic experts and surgeons during repair of the cleft palate and lip.

Contribución al Estudio Descriptivo del Foramen y Canal Palatino Mayor / Contribution to the Descriptive Study of the Foramen and Greater Palatine Canal

RESUMEN: El foramen y canal palatino mayor (FPM y CPM) comunican boca con fosa pterigopalatina. El conocimiento adecuado de su morfología, permite el abordaje anestésico del nervio maxilar. En el vivo, el FPM está recubierto por una mucosa gruesa, debido a esto los puntos de referencia óseos y dentarios son importantes para ubicar el sitio de punción. Se ha descrito gran variabilidad en cuanto a la etnia, posición, forma, diámetros, longitudes y permeabilidad. Este estudio tuvo como objetivo describir éstas características en cráneos de adultos chilenos. Se utilizaron 31 cráneos de ambos sexos. En los paladares se determinó; forma, largo, profundidad y ancho. En los FPM se consideró su forma, diámetros y localización. En los CPM se registró su permeabilidad y su coincidencia con la forma del FPM. Los registros se realizaron con cámara digital, compás de precisión, caliper digital, compas tridimensional de Korkhaus y sonda metálica. Los resultados muestran un predominio de la forma cuadrada del paladar por sobre las formas triangular y redondeada. Las mediciones de su largo, ancho y profundidad indican diferencias por sexo y por etnia. La forma del FPM no muestra diferencia por sexo, primando la forma ovalada por sobre la fusiforme y la redondeada. La posición de este mismo foramen tampoco muestra diferencias sexuales, primando la posición frente al tercer molar superior, seguida por la posición frente al espacio entre segundo y tercer molar superior y por último frente al 2do molar superior. Las dimensiones del FPM son mayores en individuos masculinos. Los CPM se observaron en su totalidad permeables y los FPM no siempre coincidieron en forma con la sección transversal del CPM. Estos resultados y su comparación con la literatura indican variaciones importantes, lo que impide establecer directrices objetivas a la técnica anestésica que utiliza esta vía anatómica.

ABSTRACT: The greater palatine foramen and canal (GPF and GPC) communicate with the pterygopalatine fossa. The adequate knowledge of its morphology allows the anesthetic approach of the maxillary nerve. In vivo, the GPF is covered by a thick mucosa, therefore, the bone and dental reference points are important to locate the puncture site. Great variability has been described in terms of ethnicity, position, shape, diameters, lengths and permeability. The objective of this study was to describe these characteristics in skulls of Chilean adults. 31 skulls of both sexes were used. In the palates shape, length, depth and width were determined. In the GPF its shape, diameters and location were considered. In the GPC, their permeability and their coincidence with the shape of the GPF were recorded. The records were made with digital camera, precision compass, digital caliper, Korkhaus three-dimensional compass and metallic probe. The results show a predominance of the square shape of the palate over the triangular and rounded forms. The measurements of its length, width and depth indicate differences by sex and ethnicity. The shape of the GPF shows no difference by sex, with the oval shape prevailing over the fusiform and the rounded. The position of this same foramen also shows no sexual differences, with the position prevailing against the upper third molar, followed by the position in front of the space between the upper second and third molars and finally against the upper 2-molar. The dimensions of GPF are greater in male individuals. The GPC were found to be entirely permeable and the GPF did not always coincide in form with the cross section of the GPC. These results and their comparison with the literature indicate important variations, which prevents establishing objective guidelines for the anesthetic technique used in these cases.

Recubrimiento del lecho amigdalino en amigdalectomía intracapsular. Reporte de técnica quirúrgica / Coating of the tonsillar bed in intracapsular tonsillectomy. Surgical technique report

El recubrimiento del lecho amigdalino se trata de un procedimiento coadyuvante y sencillo ya descrito por varios autores con diferencias en la técnica que ocupa unos cuantos minutos más en la cirugía amigdalina tradicional, pero que representa en la experiencia de muchos un aporte para la pronta cicatrización y recuperación de los pacientes sometidos a esta cirugía que se realiza desde hace mucho tiempo, pero que implica un postoperatorio particularmente molesto por cuenta del dolor en los días siguientes. Es un reto y una responsabilidad el alivio del dolor postoperatorio y la prevención de las complicaciones relacionadas principalmente con el sangrado. La intención de este artículo es proponer en la práctica diaria, cuando se realizan amigdalectomías, una técnica complementaria que mejorará las condiciones de un período postoperatorio con menor dolor y una recuperación más rápida. Se busca el recubrimiento de la zona operada con el remanente de la mucosa de la cápsula amigdalina protegiendo la musculatura del lecho.

The covering of the tonsillar bed is a simple procedure already described by several authors with differences in the technique that occupies a few minutes more in the traditional tonsillectomy, but that represents, in the experience of many, a contribution for the early healing and recovery of patients submitted to this surgery that has been performed since long time ago, but that embodies a particularly annoying postoperative period due to pain in the following days. It is our challenge and responsibility to relieve postoperative pain and prevent complications mainly related to bleeding. The intention of this article is to propose in our daily practice, when it is performed tonsillectomies, a complementary technique that will improve the conditions of a postoperative period with less pain and quick recovery. The coating of the operated area is sought with the remaining mucosa of the tonsillar capsule protecting the musculature of the tonsillar bed.

A Case of Adenosquamous Carcinoma Arising from the Tonsil / 대한이비인후과학회지

Adenosquamous cell carcinoma of tonsil is a rare lesion of head and neck and is often misdiagnosed as squamous cell carcinoma. It has a very aggressive clinical pattern. We encountered a patient with an adenosquamous cell carcinoma of tonsil and performed various treatment modalities including surgical resection, radiation therapy, chemotherapy but the patient expired two years after the first diagnosis. Such case has never been reported earlier in Korea. Herein, we present this rare case with a review of related literature.