ABSTRACT
The prognosis of pancreatic neuroendocrine neoplasms is significantly better than that of pancreatic cancer.Locally advanced pancreatic neuroendocrine tumors can invade the superior mesenteric vein,portal vein,superior mesenteric artery,celiac artery and other large peripancreatic vessels.Preoperative comprehensive examination should be carried out to evaluate and judge the resectability and biological characteristics of the tumor and select appropriate preoperative treatment.Surgical treatment can not only achieve the radical resection of the tumor,but also avoid the complications caused by the continued progress of the tumor.Combined portal vein-superior mesenteric vein and celiac artery resection and reconstruction is safe and effective.Combined superior mesenteric artery resection is worth further exploration and accumulation of experience.