Assessment of alveolar bone mass using radio morphometric indices in urban and rural postmenopausal women and their correlation with serum vitamin D3 level

Introduction: The number of women with osteoporosis i.e. with reduced bone mass and disruption of bone architecture, is increasing in India due to severe deficiency of Vitamin D. It has been reported throughout the country in urban and rural post-menopausal women. Vitamin D synthesis is affected by geographical location, atmospheric pollution, clothing, melanin pigmentation and sunlight exposure. Moreover, ageing is also associated with decreased vitamin D synthesis. Vitamin D deficiency is the most underdiagnosed medical condition in postmenopausal woman. Objective: Therefore, this study was planned to estimate and to evaluate alveolar bone mass using radio morphometric indices in postmenopausal women and its correlation with serum vitamin D3. Materials and Methods: We conducted a study comprising of a study group of 60 post-menopausal women, divided into 2 sub-groups, each group comprising of 30 individuals, depending on their occupation and domicile. Blood samples were taken to evaluate serum vitamin D3 level. Also, panoramic radiographs of all the study subjects were recorded for evaluation of 3 radio morphometric indices viz. mandibular cortical index (MCI), mental index (MI), and panoramic mandibular index (PMI). Results: Statistical analysis revealed higher significant values in rural than in urban postmenopausal woman. Conclusions: A high overall prevalence (90%) of vitamin D deficiency was also observed in the study subjects.

Panoramic mandibular index: Effect of age and gender related variations in the North-Indian population.

Background: Panoramic Mandibular Index (PMI) is a quantitative radiomorphometric index of the mandible. It is an important indicator of mandibular bone mineral density. Objectives: To examine the age and gender related variations associated with the panoramic mandibular index and their effect in a group of North-Indian population of Haryana. Methods: 60 adult human orthopantomographs were evaluated and divided into six age groups (35-65 years) with equal number of males and females. Panoramic mandibular index was measured bilaterally on every radiograph. The measurements were analyzed for interactions with age and sex, using SPSS (Stastistical Package for Social Studies) software version no. 18. The tests employed were Kruskal-Wallis, Mann-Whitney and the unpaired T-test. Results: The male mean panoramic mandibular index values ranged from 0.3 ± 0.025 to 0.381 ± 0.019, whereas the female mean panoramic mandibular values ranged from 0.286 ± 0.306 to 0.36 ± 0.007. Panoramic mandibular index showed significant negative correlation with age in both the sexes. Inter-age group comparisons showed statistically significant differences between the youngest and eldest age-groups in both the genders. Female values were lower than male values in all age groups, but sexual dimorphism was not observed. Conclusion: Panoramic mandibular index was influenced significantly by the variations in age but minimally by the gender related variations.

Research on mandibular bone mineral density in patients with end-stage renal disease / 天津医药

Objective To investigate the effectiveness of panoramic mandibular index (PMI) in detecting the bone mineral density (BMD) of mandibular bone and whole-body bone in patients with chronic end-stage renal failure. Methods A total of thirty patients with peritoneal dialysis treatment were used as experimental group and 31 healthy adults were used as control group. The panoramic jaw tomography was taken for the measurement of superior PMI (sPMI) and inferior PMI (iPMI) in two groups. The dual-energy X-ray absorptiometry (DXA) was used to detect BMD of lumbar spine bone. Data were compared between two groups. The correlation of sPMI, iPMI and BMD of lumbar spine bone was analyzed. Results All indicators including sPMI(0.262 2 ± 0.026 7 vs 0.284 2 ± 0.025 4, t=3.301) , iPMI (0.314 1 ± 0.028 3 vs 0.334 1 ± 0.027 5, t=2.808) and BMD of lumbar spine bone (0.832 3 ± 0.101 0 vs 0.906 9 ± 0.113 6,t=2.709) were significantly lower in experimental group than those in control group (P＜0.01). There was a positive correlation between sPMI and iPMI with BMD of lumbar spine bone (r=0.439 and 0.389, P＜0.05). The BMD of lumbar spine bone was significantly lower in female patients than that of male patients in control group (0.849 7±0.114 7 vs 0.968 0±0.076 3,t=3.357). The BMD of lumbar spine bone was also significantly lower in female patients than that of male patients in experimental group (0.775 4±0.068 4 vs 0.882 1±0.099 9,t=3.365). There were no significant differences in values of sPMI and iPMI between male and female patients of two groups. Conclusion The BMD of mandibular bone is lower in patients with chronic end-stage renal failure than that of the normal people. PMI index is a simple and effective method to detect the BMD of mandibular bone, which can reflect the BMD of whole body bone in patients with chronic end-stage renal disease.

Alveolar bone mass in pre- and postmenopausal women with serum calcium as a marker: A comparative study.

Context: In most women bone mass reaches its peak in the third decade of life and declines thereafter with the onset of menopause and might lead to osteoporosis. Osteoporosis may result in reduced jaw bone mass and alterations of the mandibular structure. Qualitative and quantitative indices have been used for panoramic radiographs to assess the alveolar bone quality. Aims: The purpose of this study was to compare the alveolar bone quality of premenopausal and postmenopausal women using the panoramic mandibular index (PMI). This study also aimed to estimate the levels of serum calcium in premenopausal and postmenopausal women. Settings and Design: Single centre case control study. Materials and Methods: A total of 30 patients were divided into three groups of ten each - the healthy group, control group, and study group. Alveolar bone mass was evaluated by the PMI. Serum calcium was also assessed for all the patients. Statistical analysis used: The results obtained were subjected to statistical analysis by one-way analysis of variance using Statistical Software SPSS version 17, Tukey test for comparision, Pearson's correlation coefficient was employed. Results: Premenopausal women had the highest values for alveolar cortical bone mass as recorded by the PMI, followed by postmenopausal women with a healthy periodontium. The lowest values were recorded in the group of postmenopausal women with chronic generalized periodontitis. Similar results were found for serum calcium values. Conclusion: Postmenopausal women exhibit a reduced alveolar bone mass and lowered levels of serum total calcium with the increasing age. These changes may be useful indicators for low skeletal bone mineral density or osteoporosis.

Assessing mandibular bone mineral density with morphometric analysis / 第二军医大学学报

Objective: To determine the effectiveness and validity of morphometric analysis made from dental panoramic tomograms (DPTs) for predicting mandibular bone mineral density (BMD) while taking the result of dual energy X-ray absorptiometry (DXA) as gold standard. Methods: Twenty healthy subjects (8 male, 12 female) with intact dentition, aged from 11-26 years old, were included in the present study. The BMD of each patient was measured at the lumbar spine (L1 -L4,) by DXA; the results were obtained based on the density of surface (g/cm2). Dental panoramic radiography was carried out using dental panoramic tomography (RTG230/ ENR, made in Italy). Mandibular cortical thickness (MCT) and panoramic mandibular index (PMI) values were calculated and their relationship with DXA measurements were subjected to correlation analysis. The validity of MCT and PMI measurements were assessed by sensitivity and specificity. Results: We found mandibular BMD was positively correlated with MCT (r=0. 268, P<0. 05) and PMI (r=0. 251 3, P<0. 05). The sensitivity, specificity and Youden index of MCT were 50%, 93. 75%, and 0. 437 5, respectively; the numbers of PMI were 50%, 87. 50%, and 0.375, respectively. Conclusion: MCT and PMI might be potential indicators for mandibular BMD; they are simple and applicable in clinic.

Dental panoramic radiograph as a tool for detecting bone mineral density in young adults with moderate periodontitis / 实用口腔医学杂志

Objectives:To clarify whether the bone mineral density (BMD) differed from normal and whether the mandibular BMD changed with age in young adults with moderate periodontitis. Methods:30 patients (20-35 years old) with moderate adult periodontitis and 30 individuals (20-35 years old) with normal periodontal condition as control group were included in present study. BMD of the mandible was measured using panoramic mandibular index(PMI) from panoramic radiographic film. Results:The sPMI and iPMI value were 0.275 0?0.034 and 0.527 3?0.096 (normal group), 0.223 3?0.024 and 0.367 3?0.069 (periodontitis patients) respectively.The PMI value of periodontitis patients was significantly decreased compared to that of normal group, and showed a significant correlation with age.Conclusions:Moderate periodontitis in young adults seem to be a local disorder associated with relatively low PMI in the jaws. Age-related decrease in mean PMI with increasing age in both normal and periodontitis patients is founded.Dental panoramic radiograph may serve as a simple tool in mandibular BMD defection.

Assessing mandibular bone mineral density with morphometric analysis / 第二军医大学学报

Objective:To determine the effectiveness and validity of morphometric analysis made from dental panoramic tomograms(DPTs) for predicting mandibular bone mineral density(BMD) while taking the result of dual energy X-ray absorptiometry(DXA) as gold standard.Methods: Twenty healthy subjects(8 male,12 female) with intact dentition,aged from 1126 years old,were included in the present study.The BMD of each patient was measured at the lumbar spine(L1-L4) by DXA;the results were obtained based on the density of surface(g/cm2).Dental panoramic radiography was carried out using dental panoramic tomography(RTG230/ENR,made in Italy).Mandibular cortical thickness(MCT) and panoramic mandibular index(PMI) values were calculated and their relationship with DXA measurements were subjected to correlation analysis.The validity of MCT and PMI measurements were assessed by sensitivity and specificity.Results: We found mandibular BMD was positively correlated with MCT(r=0.268,P