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Br J Med Med Res ; 2014 Feb; 4(5): 1149-1162
Article in English | IMSEAR | ID: sea-175004

ABSTRACT

The dominant view that cancer arises from successive mutations in somatic cells is so unquestioned that accumulating challenges from experimental and observational results are rarely addressed in the scientific literature. Based on these challenges, we argue that the scientific understanding of carcinogenesis has entered a period of paradigm instability. New research directions are therefore needed.

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