"Research Progress in Prevention and Treatment of Pediatric Diseases Based on TCM Theory of""Correspondence between Man and Nature""in Chronomedicine" / 中国中医药信息杂志

Correspondence between man and nature theory is the core of TCM chronomedicine, and also plays an important role in ancient Chinese philosophy. The theory believes that distinguishing the rhythm is the foundation of treatment; complying with nature is the core of treatment; taking advantage of wane and wax is the method of treatment. This article combined the physiological and pathological characteristics of children to review the prevention and treatment of pediatric diseases based on chronomedicine, with a purpose to provide inspirations for clinical treatment.

Intervenciones de enfermería para el cuidado del paciente pediátrico con enfermedad del reflujo gastroesofágico / Interventions of infirmary for the care of pediatric patient with disease of gastroesophageal reflux

Antecedentes: Hemos creado la guía de práctica clínica de las intervenciones de enfermería para el cuidado del paciente pediátrico con enfermedad de reflujo gastroesofágico.Métodos: Esta guía de intervención de la práctica clínica de Enfermería forma parte de los guías que integran el Catálogo General de la Práctica Clínica, la cual se instrumentó a través del programa de acción específico: Guías de desarrollo de la práctica clínica, de acuerdo con las estrategias y líneas de acción que considera el Programa Nacional de Salud. 2013-2018 Esta guía de práctica clínica guiará al profesional de la salud para que otorgue cuidados especiales a este tipo de pacientes, al mismo tiempo que se basa en el conocimiento actualizado y estandarizado que fundamenta la evidencia y la toma de decisiones que favorecen la calidad de vida del paciente con la enfermedad de reflujo gastroesofágico, disminuyendo así las complicaciones y la mortalidad súbita. Y al mismo tiempo aumentar la eficiencia del proceso de atención en la enfermería propiciando un cuidado seguro y libre de riesgos.Resultados: Se favorecerá la mejora de la eficiencia, seguridad y calidad de la atención que contribuye, por la presente, para el bienestar de la gente y de las comunidades, que es el objetivo central y la razón de ser de los servicios de salud.Conclusión: el propósito de este catálogo es establecer un estandar nacional para orientar las decisiones clínicas de guía basadas en las recomendaciones sufridas en la mejor evidencia disponible y que tiene las intervenciones dirigidas a la identificación oportuna de los signos y síntomas y complicaciones, así como intervenciones de colaboración para el tratamiento y medidas de seguridad.

Background: We created the guide of clinical practice of interventions of infirmary for the care of pediatric patient with disease of gastroesophageal reflux. Methods: This guide of clinical practice intervention of infirmary forms a part of the guides who integrate the Guides' Main Catalogue of Clinical Practice, which is orchestrated across the Specific Program of Action: Guides' Development of Clinical Practice, according to the strategies and lines of action that considers 2013-2018 National Health program. This guide of clinical practice will guide the professional of health provider to taken care this type of patients, rely on updated and standardized knowledge based on the evidence and to take decisions that affect favorably the quality of life of the patient with gastroesophageal reflux disease as well as to diminish complications, sudden mortality, increase the efficiency of the process of care in infirmary and to propitiate a sure and free care of risks.Results: it will favor the improvement of the efficiency, safety and quality of the care contributing, hereby, to the wellbeing of the people and of the communities, which it is the central aim and the reason to be of health services. Conclusion: the purpose of this catalog is to establish national modal to orientate the guide clinical decisions based on recommendations sustained in the best available evidence and having interventions directed to the opportune identification of signs and symptoms and complications as well as collaborative interventions for the treatment and safety measures.

Antecedentes: Criamos o guia da prática clínica de intervenções de enfermaria para o atendimento de pacientes pediátricos com a doença do refluxo gastroesofágico.Métodos: Este guia de intervenção prática clínica da enfermaria faz parte dos guias que integram 'principal Catalogue of Clinical Practice, que é orquestrada em todo o programa de acção específicos: Guias' as Guias de Desenvolvimento da prática clínica, de acordo com as estratégias e linhas de ação que considera 2013-2018 programa Nacional de Saúde. Este guia da prática clínica vai orientar o profissional de prestador de cuidados este tipo de pacientes, dependem de conhecimento atualizado e padronizado com base nas provas e tomar decisões que afectam favoravelmente a qualidade de vida do paciente com doença do refluxo gastroesofágico, bem de modo a diminuir as complicações, a mortalidade súbita, aumentar a eficiência do processo de atendimento em enfermaria e propiciar um atendimento seguro e livre de riscos. Resultado: ele vai favorecer a melhoria da eficiência, segurança e qualidade do contribuinte cuidado, por este meio, para o bem-estar das pessoas e das comunidades, que é o objetivo central e a razão de ser dos serviços de saúde.Conclusão: o objectivo deste catálogo é estabelecer modal nacional para orientar as decisões clínicas de orientação com base nas recomendações sustentadas na melhor evidência disponível e com intervenções dirigidas à identificação oportuna de sinais e sintomas e complicações, bem como intervenções de colaboração para o tratamento e medidas de segurança.

CD40-CD40 ligand in pediatric disease / 国际儿科学杂志

CD40-CD40 ligand (CD40-CD40L) cross-linking,an important cell signaling transduction pathway in immune response,is involved in the regulation of cellular and humoral immune.CD40-CD40L signaling pathway abnormalities can lead to immune system disorders and incur immune pathological reaction.A variety of common pediatric diseases,such as immunodeficiency diseases,inflammatory diseases and autoimmune diseases,are associated with CD40-CD40L signaling transduction pathway abnormalities.The relationship between CD40-CD40L and the above-mentioned diseases is of clinical significance.

Preventing catheter-associated infections in the Pediatric Intensive Care Unit: impact of an educational program surveying policies for insertion and care of central venous catheters in a Brazilian teaching hospital

Objectives: To determine the impact of an educational program on the prevention of central venous catheter-related infections in a Brazilian Pediatric Intensive Care Unit. Patients and Methods: All patients admitted to the unit between February 2004 and May 2005 were included in the cohort study in a longitudinal assessment. An educational program was developed based on the Centers for Disease Control and Prevention recommendations for prevention of catheter-associated infections and was adapted to local conditions and resources after an initial observational phase. Incidence of catheter-associated infections was measured by means of on-site surveillance. Results: One hundred eighteen nosocomial infections occurred in 253 patients (46.6 infections per 100 admissions) and in 2,954 patient-days (39.9 infections per 1,000 patient-days). The incidence-density of catheter infections was 31.1 episodes per 1.000 venous central catheter-days before interventions, and 16.5 episodes per 1,000 venous central catheter-days afterwards (relative risk 0.53 [95 percent CI 0.28-1.01]). Corresponding rates for exit-site catheter infections were 8.0 and 2.5 episodes per 1,000 venous central catheter-days [0.32 (0.07-1.49)], and the rates for bloodstream infections were 23.1 and 13.9 episodes per 1,000 venous central catheter-days, before and after interventions [0.61 (0.32-1.14)]. Conclusion: A prevention strategy targeted at the insertion and maintenance of vascular access can decrease rates of vascular-access infections in pediatric intensive care unit.