ABSTRACT
In Bangladesh conditions, the end of the Boro season begins floods and natural calamities and loses more rice in farmer's fields. If we can select early maturity genotypes for the Boro season, we can harvest our rice from the farmer's field before flooding or any other natural calamities. The study attempted to determine the short duration and high yielding rice genotype for Boro season in Bangladesh amongst the 13 Boro rice F6 lines by contrast with two (2) test varieties. Keeping in view this idea, the output of the genotypes studied, the relationship between different morpho-physio-chemical and yield-contributing characteristics between all the genotypes were investigated there under field and laboratory conditions. Among these 15 lines, G11 line showed better in the most yield contributing parameters. It is therefore concluded that the G11 genotype will be considered an appropriate line for the Boro season in Bangladesh.
ABSTRACT
@#Introduction: With the increasing clinical use of titanium dioxide nanoparticles (nano-TiO2), a better understanding of their safety in the human use is critical. The present study aims to review the potential application of nano-TiO2 as targeted cancer therapy based on their toxicity risk which highly dependent on their physio-chemical properties. Methods: This review was performed based on PRISMA-P protocol that begin with literature searching on the selected databases; PubMed, Springer Link, Science Direct and general search engine; Google Scholar from 2013 to 2018. Studies retrieved by the pre-determined keywords (titanium dioxide nanoparticles, toxicity, genotoxicity, cytotoxicity, targeted cancer therapy) that assessed toxicity risk of nano-TiO2 in cancer therapeutics were included. Results: The search retrieved 252 articles. Assessment of eligibility by application of inclusion criteria yielded 14 articles. Nano-TiO2 induced cytotoxicity and genotoxicity in dose and time-dependent manner killing the cancerous cells. All studies used primary particles size < 100 nm with mean of 39.38 and standard deviation of 30.47 which is lower than the mean denoting diameter distribution from selected studies are concentrated from the mean. Conclusion: This review suggest that TiO2 nanoparticles can be considered as an ideal candidate for drug-delivery vehicle for targeted cancer therapy by specifically tailored their physio-chemical properties of this nanoparticles according to desired target site and functions to ensure its optimal efficacy.