ABSTRACT
Objective Tomeasurecerebralbloodflow (CBF)inpatientswith middlecerebralartery (MCA)stenosisoracute stroke.Methods SeventyGonepatientswithstenoticMCAoracutestrokewererecruitedandclassifiedintofourgroups:mild MCA stenosis,severeMCAstenosis,occluded MCAandacutestroke.TheacquisitionprotocolsincludedASLsequence.CBFwereobtained from ASLsequence.CBFwasmeasuredandaveragedintheregionssuppliedby MCA.Theratiosoflesion/contralateralhemispheric CBFvaluesweredefinedastherelativeCBF (rCBF).Alldatawereperformedstatisticalanalyze.Results Thehemisphereswithstenotic MCAoracutestrokeshowedasignificantlylowerCBFthanthecontralateralhemispheres.TherewerenointerGgroupdifferencesin thecontralateralhemisphereCBFamongfourgroups.Additionally,significantdifferencesinlesionCBFandrCBF werefoundinthe foursubgroups.Patientswithoccluded MCAshowedthesamerCBFasthatwithacutestroke.Conclusion WiththedegreeofMCA stenosisaggravating,CBFdecreasesintheterritorysuppliedby MCA.Moreover,thepatientswhoseCBFislowerthan33.33 mL??min－1??100g－1orrCBFislowerthan0.69shouldperformactivetreatment.