ABSTRACT
@#AIM: To explore the clinical curative effect of semi-panretinal laser photocoagulation in treatment of the prethreshold and threshold retinopathy of premature(ROP)infants.<p>METHODS:Totally 25 patients with ROP were selected, 24 eyes of prethreshold, 22 eyes of threshold period. All preterm infants(46 eyes)were given semi-panretinal laser photocoagulation vialaser indirect ophthalmoscopy and completed the 42-881(362±59.6)d follow-up period.<p>RESULTS: ROP regressed after single photocoagulation in 38 eyes(83%)and in 8 eyes(17%)after the second photocoagulation totally. No infants had localized proliferation or detachment post total treatment. The regression of retinopathy was found in 22 eyes in prethreshold group(92%)and in 16 eyes in threshold group(73%), while the difference was statistically significant(<i>P</i><0.05).<p>CONCLUSION: The effects of semi-panretinal laser photocoagulation in treatment of the prethreshold and threshold ROP are quite. The benefits of protected larger vision field have the potential to improve ROP outcomes.