ABSTRACT
The purpose of this study was to determine the loss of visceral fat during weight loss program with diet only or diet plus exercise in premenopausal obese women (age 44±6 yr) . One hundred seventeen women (body mass index 29±3 kg /m<SUP>2</SUP>) were divided into diet only group (DO, n=40) and diet plus exercise group (DE, n=77) . DE was further divided into two groups: a group with a small change in VO<SUB>2</SUB>max (DE<SUB>1</SUB>, n=26) and a group with a large change in VO<SUB>2</SUB>max (DE<SUB>2</SUB>, n=51) . Height, weight, fat mass, %fat, fat-free mass (FFM), abdominal total fat area (TFA), visceral fat area (VFA), subcutaneous fat area (SFA) and VO<SUB>2</SUB>max (ml/kg FFM/min) were measured before and after weight loss. The changes of weight, fat mass, %fat were significantly larger in DE than in DO. No difference was found in the changes of weight, fat mass, %fat between the DE<SUB>1</SUB> and DE<SUB>2</SUB>. Percentage of change in VFA was significantly larger in DE<SUB>2</SUB> (41±15%) than in DE<SUB>1</SUB> (31±16%) . These data suggest that both weight-loss programs (DO and DE) contribute to a remarkable decrease in visceral fat. Addition of exercise training, which would induce an improvement in VO<SUB>2</SUB>max, to dietary restriction, may elicit a greater effect on visceral fat.
ABSTRACT
The purpose of the present study was to investigate the relationships of physical fitness, body mass index (BMI), waist-hip ratio (WHR) and sex hormone binding globulin (SHBG) with lipid and glucose metabolism in premenopausal obese women aged 32 to 49 yrs (n=24) . WHR was significantly correlated with HDL-C, HDL<SUB>2</SUB>-C and Apo B, but not correlated with BMI %fat, maximal oxygen uptake (VO<SUB>2</SUB>max), triglyceride (TG), very low density lipoprotein % fat, and Apo A 1. VO<SUB>2</SUB>max/kg was significantly associated with BMI, TG, HDL-C, HDL<SUB>2</SUB>-C, Apo Al, low density lipoprotein (LDL), SHBG, glucose metabolism at rest and during oral glucose tolerance test (OGTT) . The SHBG was strongly correlated with HDL-C, HDL<SUB>2</SUB>-C and Apo A 1. In multiple regression analysis, it was observed that SHBG was one of the independ-ent predictor of HDL-C, HDL<SUB>2</SUB>-C and Apo Al, that VO<SUB>2</SUB>max was good predictor of LDL, Apo B and glucose metabolism at rest and during OGTT, and that BMI was one of the determinat of TG and VLDL. From these results, we concluded that lipid metabolism was independently associated with aerobic work capacity, SHBG, BMI as well as WHR, and that glucose metabolism was independently associated with aerobic work capacity.