Traditional Chinese medicine (tumor) prevention and evaluation model based on ultra-early immune response information amplification index naCTL and multidimensional immunoinformatic index TCR/BCR/HLA effective diversity / 中国中药杂志

The best time of tumor intervention is before the formation of tumor. However,due to the limited number of tumor cells,it is difficult to quantify tumor cells and immunity by the current methods available( such as CTC,ct DNA). This affects the tumor prevention in this period,and the in-depth detection,intervention and evaluation of traditional Chinese medicine( TCM)( tumor) prevention. Due to the limitations of the current detection,the evaluation system turns to detect tumor neoantigen-specific CTL( naCTL) that are directly relating to tumor cells and proliferate to high order of magnitudes after activation,and immune repertoire( TCR/BCR/HLA) effective diversity,introduces immune checkpoints,uses information of " disease" in Western medicine and " syndrome" in TCM( prevention),and sets up a multi-dimensional statistical immunity model using a variety of data analysis and related algorithms. This model can amplify the ultra-early information of tumor,indirectly evaluate the quantity and status of tumor cells,and provide quantitative measurement and new evaluation methods for the normalization of immunity and TCM( tumor) prevention. This model is not only one of important evaluation methods for resisting tumor immunity and treating TCM( tumor) prevention,but also will reveal the scientific connotation of TCM syndrome from the perspective of immunology.

Relationship of orthodontic treatment and periodontal soft tissue health / 华西口腔医学杂志

With the increasing number of the orthodontic patients, the relationship between periodontal and orthodontic becomes increasingly close. Orthodontic treatment can improve periodontal status, but the adverse clinical problems of periodontal tissue during orthodontic treatment are relatively common. In this paper, we discuss the problems of soft tissue, including causes, prevention, and treatment of gingivitis, gingival enlargement, gingival recession, and gingival invagination in orthodontic treatment.

Discussion on Applying Removing Blood Stasis and Body Fluid Therapy as Principal of Treating Orthopedics and Traumatology Diseases / 中国中医药信息杂志

Blood stasis is mostly seen as the etiology and pathogenesis of orthopedics and traumatology diseases, among which the theory that retention of body fluid comes from blood stasis is the most classical one. Thus, it is meaningful to find out whether the mutual blockage of blood stasis and the body fluid is the key point of orthopedics and traumatology diseases. By consulting the ancient books, the significance of removing blood stasis and body fluid therapy was verified from different aspects, and removing blood stasis and body fluid therapy was proposed to be the principle of treating orthopedics and traumatology diseases.