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There exits a trend of treatment for coronary heart disease(CHD) in terms of Chinese medicine(CM) in history,from warming Yang and dispelling cold,moving Qi and dissolving phlegm to invigorating blood and dissolving stasis,whose time-space development accords to the theory of complex system.Targeting the contemporary population of CHD,phlegm-blood stasis-stagnation-deficiency theory is proposed to direct clinical application to further improve effectiveness.From the perspective of theory,blood stasis-stagnation is the basic pathogenesis of CHD that runs through the whole period in the advance of CHD,while phlegm has been changing the feature of CM Zheng of CHD population with the development of the society,and nourishing the body according to the type of deficiency might delay the process of growing older,postpone the occur of disease and hinder the advance of disease,which genuinely differs from modern medicine to render the superiority of CM to work out the challenges of CHD.As for the clinical application,the treatment options could consider invigorating blood,dissolving stasis and removing stagnation as the basic method,such as CHD formula 2,Xuefu Zhuyutang,Zhizi Chitang and Danggui Niantongtang could be used in varied period of CHD.Moreover,boosting the body by herbal medicine could regulate the routine of body,then to prevent CHD and fear down the advance of CHD,for instance,Codonopsis Radix,Astragali Radix,Liuwei Dihuang pills,Zuoguiyin and Youguiyin.Furthermore,balmiest herbs could not only dissolve phlegm,unblock the meridian and relieve pain,but also calm the mind and eliminate the anxiety.For example,Aquilariae Lignum Resinatum,Santali Albi Lignum and Moschus could be used handily in the treatment of CHD.
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ObjectiveAnalyze the mechanism of traditional Chinese medicine Salvia miltiorrhiza in treating coronary heart disease (CHD).MethodsThe animal experiment using actual research, namely the selection of rat isolated heart perfusion model, rat model of myocardial ischemia and ventricular tachycardia in rabbits model, then the effects of different animal groups in hemodynamics, coronary flow, serum superoxide dismutase (SOD) content, malondialdehyde (MDA) the results of the content.ResultsAfter treatment, the content of SOD was significantly increased and the content of MDA was significantly decreased in the treatment group, and the difference between the two groups was statistically significant (P<0.05).ConclusionTraditional chinese medicine Salvia miltiorrhiza has significant effect on the treatment of coronary heart disease, which is beneficial to the recovery of patients' condition, and is worthy of clinical application.
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[Objective] To explore the clinical experience of Professor ZHOU Xiaohong in treating chronic atrophic gastritis(CAG) from blood stasis.[Methods]Through the analysis of literature,tracing the source of the disease,following the teacher clinic and collecting relevant medical records,Professor ZHOU Xiaohong's clinical experience in treating CAG from blood stasis is summarized from the aspects of etiology,pathogenesis,treatment and so on.At the same time,the characteristics of the prescription of herbal are summarized,and exemplify that.[Result]Professor ZHOU Xiaohong thinks that blood stasis is the basic pathological factor of CAG.It plays an important role in the occurrence and development of this disease,and blood circulation and blood stasis should be carried through the whole process of clinical syndrome differentiation and treatment.ZHOU attachs importance to the application of drugs for promoting blood circulation to remove blood stasis,such as syndrome differentiation,disease differentiation,experience.In addition,another key view is the selection of drugs that can activate blood circulation to remove blood stasis,combining with modern research.The uhimatc result is to promote rcstoration of the gastric mucosa and absorption of local inflammation,enhance and improve the function of gastric mucosal barrier,reduce the degree of glandular atrophy,prevent cancer,and,thus significantly improve clinical efficacy.[Conclusion] Professor ZHOU Xiaohong has rich clinical experience and unique opinion in treatment of CAG.The clinical curative effect of CAG from the treatment of blood stasis is significant,which is worth learning and popularizing.
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Objective To observe the clinical effects of the method of reinforcing qi,nourish ing yin and promoting blood circulation to remove blood stasis in the treatment of restenosis after percutaneous coronary intervention.Methods 60 coronary heart disease patients who had accepted PCI treatment and occurred restenosis were randomly recruited into a control group and a treatment group,30 eases in each group.The control group received conventional therapy.The treatment group was treated with conventional therapy combined with TCM of reinforcing qi,nourishing yin and promoting blood circulation to remove blood stasis.Both groups were treated for 6 months.The clinical symptoms,coronary angiography or coronary artery CTA,blood lipids were observed.Results The total effective rate was 93.33％ and 66.67％ in the treatment group and the control group respectively,showing statistical difference (x2=8.787,P＜0.05).The patients' clinical symptoms in the treatment group were improved,such as chest pain,chest tightness,shortness of breath,fatigue,dry mouth [The scores were respectively(1.07± 1.01)、(1.33±1.21)、(1.47±1.17)、(1.53±1.14)、(1.53± 1.01),(P＜0.05) ].The treatment group demonstrated a significantly better therapeutic results than the control group [Thescoreswererespectively(2.07±1.53)、(2.27±1.46)、(3.73±1.46)、(3.73±1.87)、(3.13±1.63),(P＜0.05) ].The results of coronary angiography or coronary artery CTA showed that the narrow degree in the treatment group was no more aggravating and it had no new restenosis.After the treatment,the level of CHOL、TG、HDL-C、LDL-C in the treatment group was improved [They were respectively (4.55±0.44)mmol/L、(1.81±0.56)mmol/L、(1.26±0.38)mmol/L、(2.25±0.49)mmol/L,(P＜0.05) ].The improvement in CHOL、TG、LDL-C of the treatment group was better than that of the control group [They were respectively (4.86±0.63)mmol/L、(2.29±1.06)mmol/L,(2.60±0.73)mmol/L,(P＜0.05)].Conclusion The method of reinforcing qi,nourishing yin and promoting blood circulation to remove blood stasis could improve the patients clinical symptoms and blood lipids,and therefore spreventing restenosis.
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OBJECTIVE:To classify the herbs for promoting blood circulation to remove blood stasis.METHODS:Database of 33 commonly used herbs for promoting blood circulation to remove blood stasis was established by means of SPSS10.0 software package;and the nature,tastes,meridian attributions and actions of the herbs were collected as variables showing the characteristics of classification,and the names of the herbs served as variables for measurement to proceed Q Cluster in Hierarchical Cluster.RESULTS:When the herbs were classified into 4 groups,the first group included the herbs for promoting blood circulation to restore menstrual flow,the second the herbs for promoting blood circulation to arrest pain and dissipate tumor,the third the herbs of herbs for activating blood circulation to dissipate blood stasis and kill pain,the fourth the herbs for severely activating blood circulation to dissipate blood stasis.When the herbs were classified into 5 groups,the fifth group included herbs for activating blood circulation to cure wound.When the herbs were classified into 6 groups,the third one included the herbs for activating blood circulation to exclude wind and the sixth the herbs for activating blood circulation to stanch blood.CONCLUSION:Fuzzy grouping analysis can be applied to classify herbs of different kinds yet with the same efficacy and to classify the same group of herbs according to their drug actions.