Psammomatoid variant of juvenile ossifying fibroma

Juvenile ossifying fibroma (JOF) is a rare benign tumor of the craniofacial bones differing from other fibro-osseous lesions in terms of early age of onset, aggressive clinical behavior, and high recurrence rate. Histopathologically, it is divided into two as trabecular JOF (TrJOF) and psammomatoid JOF (PsJOF). In PsJOF, psammoma-like spherical ossicles constitute pathognomonic histopathological images, whereas TrJOF has trabeculae of fibrillary osteoid and woven bone. Despite the histopathologic separation, both lesions have similar clinical behavior, thus the treatment procedure is also the same. Complete surgical resection is preferred for the treatment. We report a rare case of PsJOF involving the maxillary sinus and resultant facial symmetry in a 13-year-old female child.

Psammomatous ossifying fibroma of frontal sinus: a case report with review of literature.

Psammomatoid Ossifying Fibroma (POF) is a rare, slowly progressive benign tumor of the extragnathic craniofacial bones representing a subgroup of related fibro-osseous lesions with a tendency towards locally aggressive behaviour unique to the nasal cavity, paranasal sinuses, orbit and is often misdiagnosed. Histologically they are benign, but clinically they are locally aggressive. We report a case of a 17 year-old boy who presented with psammamatous ossifying fibroma of the frontal sinus. The location of this tumor made this case unusual.

Psammomatoid Type Juvenile Ossifying Fibroma of Mandible: A Rare Entity.

Juvenile ossifying fibroma (JOF) is a rare fibro-osseous neoplasm that arises within the craniofacial bones. Two distinct histopathological variants have been described; trabecular JOF and psammomatoid JOF (PsJOF). The later occurs predominantly in craniofacial skeleton and rarely in jaws and more so in mandible (50% of the times than that in maxilla). Here we report a rare case of PsJOF in mandible body ramus region with its unique radiographic characteristics to help the diagnostician approach the diagnosis very closely for this rare entity. The tumor has been present since 1 year with unilocular radiographic appearance; having homogeneous ground-glass appearance with higher imaging, without any focal radio-opacity and inferior alveolar canal was displaced but still intact. Thus these lesions can expand to large sizes even without maturing to its radiopaque stages and without destruction of adjacent vital structures although displacing them.

Psammomatoid Ossifying Fibroma - An Unusal Presentation.

Psammomatoid juvenile ossifying fibroma (PsJOF) is a well defined clinical and histological entity with earlier onset at (childhood or adolescence) classified under the broad category of fibro-osseous lesion. Histological PsJOF is one of the entity of juvenile ossifying fibroma (JOF) characterized by small spherical ossicles resembling psammoma bodies and the other with trabecular or fibrillar osteoid and woven bone which is termed as trabecular juvenile ossifying fibroma (TrJOF). This case of PsJOF involved maxilla, premaxilla, antrum, lateral wall of nose on left side of face. The size, extent and aggressive behavior of the tumor which has lead to facial disfigurement and difficulty in breathing, inability to speak, eat and drink is rare in literature. The treatment done by resection with safe margins is adequate with no recurrence as patient is under follow up for more than one year.