ABSTRACT
@#A diving decompression procedure is a specific rule that divers should follow when they ascend and get out of water. It comes from the decompression theory and algorithm and is designed for the prevention of decompression sickness. With the ， ， development of diving technology and diving medicine the decompression procedures are constantly innovated and the new ， decompression procedure can be used in diving practice after safety verification. In principle the safety verification of ， decompression procedures should be conducted on animal experiments before human experiments and the risks of ， decompression sickness and oxygen toxicity should be systematically assessed. However the assessment methods used in ， ， ， different studies differ greatly thus it is urgent to establish a standard and universal verification system. Traditionally the risk ， ， assessment of decompression sickness and oxygen toxicity is mainly carried out by observing the incidence detecting bubbles ， theoretical calculation and lung functional test. Furthermore biochemical indicators are increasingly becoming important ， ， supplements. Due to the special underwater environment the diving operation is prone to accidents. Therefore in addition to ， verifying the safety of the new decompression procedure exploring its safety decompression limit is of great significance for the formulation of emergency decompression procedures in emergency situations. The specific approach is to shorten the decompression time and assess the safety until the critical time for detecting bubbles without the occurrence of decompression ， ， sickness is found. Future studies should continue to optimize safety assessment methods explore sensitive biochemical markers ， clarify species associations and improve verification efficiency and reliability of results.
ABSTRACT
There are so many biomechanical risk factors related with glaucoma and their relationship is much complex. This paper reviewed the state-of-the-art research works on glaucoma related mechanical effects. With regards to the development perspectives of studies on glaucoma biomechanics, a completely novel biomechanical evaluation factor -- Fractional Flow Reserve (FPR) for glaucoma was proposed, and developing clinical application oriented glaucoma risk assessment algorithm and application system by using the new techniques such as artificial intelligence and machine learning were suggested.
Subject(s)
Humans , Algorithms , Artificial Intelligence , Biomechanical Phenomena , Glaucoma , Diagnosis , Intraocular Pressure , Machine Learning , Risk Assessment , Risk FactorsABSTRACT
Breast cancer is one of the most common cancer among females.With the rise of the concept of positive psychology,the research of positive psychology of patients with breast cancer has become a current hot topic.This research reviews the development of this part from aspects of ″the influence of positive psychological factors on the quality of life in patients with breast cancer″and ″the research status of the positive psychological intervention of patients with breast cancer″,in order to provide the reference for building a better psychological nursing intervention model of patients with breast cancer.
ABSTRACT
Recently, the incidence of colorectal cancer in China has increased yearly, and it has become one of the most common ma-lignant tumors of the digestive tract. With in-depth molecular biology and metagenomics studies, it has been found that changes in the intestinal microflora and its metabolic patterns can be achieved by destroying normal tissue cell DNA, activating oncogenic signal-ing pathways and producing tumor-promoting metabolites and inhibitory antibodies. Multiple factors such as the tumor immune re-sponse affect the occurrence and development of colorectal cancer. Therefore, attempts have been made to treat and prevent tumors using microecological agents. Through research, it is found that microecological preparations represented by probiotics and excreta transplantation technology can regulate intestinal microflora, induce apoptosis and cell cycle arrest of colorectal cancer cells, secrete anti-tumor cytokines, and regulate the immune system to resist tumors. Microecological preparations have brought hope to patients with colorectal cancer, but the specific mechanism of action of intestinal microflora in colorectal cancer is still unclear, and further large-scale studies are needed. This article reviews the research progress of intestinal microflora and colorectal cancer in order to ex-plore a new method for the diagnosis and treatment of colorectal cancer.
ABSTRACT
Silent information regulator protein 1 (SlRT1) is one of the sirtuins and belongs to histone deacetyase. lts activity depends on nicotinamide adenine dinucleotide ( NAD+) and is regulated by NAD+. Experimental and clinical studies have shown the neuro-protective effect of SlRT1 in the pathogenesis of age-related eye diseases. ln this review, the relationship between SlRT1 activator and apoptosis in the retinal cells were discussed. The review also points to SlRT1 as a potential therapeutic target for the clinical management of age-related retinal disease.