ABSTRACT
Objective: To determine the prevalence of seborrhoeic dermatitis (SD) and atopic dermatitis (AD) between the Demodex folliculorum (D. folliculorum) positive and D. folliculorum negative patients and to investigate any possible relationship between the D. folliculorum mites and the presence of SD and AD. Methods: In this cross sectional study, authors collected samples from the skin around the nasal tip of 180 randomized patients who reffered to Amir Al-Momenin Hospital dermatology clinic for skin erythema, scaling and pruritis, to examine the precence of demodicosis (D. folliculorum) infestation under optical microscope. Then authors assessed the prevalence of SD and AD between the D. folliculorum positive and D. folliculorum negative patients. Finally, data analysis using SPSS software and Chi-square test were performed. Results: Our study showed no significant association between the demodicosis (D. folliculorum) and SD (P=0.68) and AD (P=0.70) prevalence. Conclusions: According to the result of this study, the eradication of Demodex mites probably is not effective to reduces the prevalence of both dermatitis. However further investigation on a larger scale in a case-control study in this area is recommended.
ABSTRACT
OBJECTIVE@#To determine the prevalence of seborrhoeic dermatitis (SD) and atopic dermatitis (AD) between the Demodex folliculorum (D. folliculorum) positive and D. folliculorum negative patients and to investigate any possible relationship between the D. folliculorum mites and the presence of SD and AD.@*METHODS@#In this cross sectional study, authors collected samples from the skin around the nasal tip of 180 randomized patients who reffered to Amir Al-Momenin Hospital dermatology clinic for skin erythema, scaling and pruritis, to examine the precence of demodicosis (D. folliculorum) infestation under optical microscope. Then authors assessed the prevalence of SD and AD between the D. folliculorum positive and D. folliculorum negative patients. Finally, data analysis using SPSS software and Chi-square test were performed.@*RESULTS@#Our study showed no significant association between the demodicosis (D. folliculorum) and SD (P=0.68) and AD (P=0.70) prevalence.@*CONCLUSIONS@#According to the result of this study, the eradication of Demodex mites probably is not effective to reduces the prevalence of both dermatitis. However further investigation on a larger scale in a case-control study in this area is recommended.
ABSTRACT
Particular types of eczema may affect up to 29% individuals in certain populations (lifetime prevalence), thus placing the diseases among most frequent clinical problems. Nevertheless, diseases from the spectrum of dermatitis and eczema are poorly defined and frequently misdiagnosed; they also frequently overlap, making the diagnostic process even more difficult. In doubtful cases, where no further means of clinical or laboratory differentiation are available, reliable epidemiological data may provide relevant help in the diagnostic process, as the best candidate for a tentative diagnosis seems the most frequent among diseases in question, which can be verified later by the effectiveness of respective treatment regimen. However, results of epidemiological studies in the field of eczema and dermatitis may be strikingly contradictory, one of the possible reasons being definitions of various types of eczema/dermatitis that leave too much space for individual decision and thus seem hardly suitable for epidemiological research. Better studies based on unequivocal definitions of various types of eczema are necessary to achieve the quality of epidemiological data that would ensure the level of certainty expected from a diagnostic tool. The present paper collates results from available epidemiological data on various types of eczema: atopic eczema, allergic and irritant contact dermatitis, protein contact dermatitis, seborrhoeic dermatitis, asteatotic dermatitis, stasis dermatitis, nummular eczema, dyshidrotic eczema (pompholyx), hand dermatitis and occupational dermatitis. Problems and possible sources of bias in available studies are addressed and discussed along with the results from the studies.