ABSTRACT
Objective:To evaluate the impact of the establishing universal basic medical insurance system(UMIS) on pharmaceutical industry in China.Methods:Based on the accumulated main business income data of China's pharmaceutical industry from 2002 to 2014,the influence change of UMIS on China's pharmaceutical industry before and after 2008 was analyzed by the segmented regression model.Results:Segmented regression model showed that the slope rate of development trend of main business income of China's pharmaceutical industry was 1.03×107 thousand yuan per quarter(P=0.000) before the implementation of UMIS in 2008.After the implementation of UMIS in 2008,the slope rate of development trend of main business income of China's pharmaceutical industry was 2.75× 107 thousand yuan per quarter (P=0.000) and trend increased 1.72× 107 thousand yuan per quarter(P=0.000).Conclusion:The UMIS had impact on the structure,sales volume of pharmaceutical products and sale costs of China's pharmaceutical industry.UMIS had a significant effect on the increase of China's pharmaceutical industry.
ABSTRACT
In many studies about biomedical research factors influence on the outcome variable,it has no influence or has a positive effect within a certain range.Exceeding a certain threshold value,the size of the effect and/or orientation will change,which called threshold effect.Whether there are threshold effects in the analysis of factors (x) on the outcome variable (y),it can be observed through a smooth curve fitting to see whether there is a piecewise linear relationship.And then using segmented regression model,LRT test and Bootstrap resampling method to analyze the threshold effect.Empower Stats software developed by American X & Y Solutions Inc has a threshold effect analysis module.You can input the threshold value at a given threshold segmentation simulated data.You may not input the threshold,but determined the optimal threshold analog data by the software automatically,and calculated the threshold confidence intervals.